Emmanuelle Apper
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View article: A new highly digestible prescription diet containing Bacillus velezensis DSM 15544, fructo-oligosaccharides, plasma immunoglobulin, yeast and sepiolite for the management of acute diarrhea in dogs—a randomized double-blinded, controlled trial
A new highly digestible prescription diet containing Bacillus velezensis DSM 15544, fructo-oligosaccharides, plasma immunoglobulin, yeast and sepiolite for the management of acute diarrhea in dogs—a randomized double-blinded, controlled trial Open
Objective To determine if a newly formulated diet with safe and highly digestible ingredients, Bacillus velezensis DSM 15544, fructo-oligosaccharides, animal plasma protein, dried whole yeast and sepiolite contributes toward the management…
Identification of immunomodulating properties of postbiotics from lactobacilli using the zebrafish (Danio rerio) model Open
Background & objectives Probiotics are increasingly used in the pet industry to enhance the health and well-being of companion animals. Among them, Lactobacillus strains and their metabolites have demonstrated the ability to maintain immun…
Supplementation of a new combination of prebiotic and postbiotic shapes fecal microbiota of old dogs while influencing immune parameters Open
Healthy senior dogs were subjected for 77 days to a dietary regime with (or without) prebiotic + postbiotic mixture composed by short-chain fructo-oligosaccharides and yeast fractions (scFOS+). Their fecal microbiota was studied and the li…
Lactobacillus helveticus-derived postbiotic and live Saccharomyces boulardii restore gut microbiota after antibiotic disturbance in an in vitro canine gut model Open
Gut microbiota plays a central role in dog health, supporting nutritional and physiological processes. However, antibiotic treatment can disturb microbiota equilibrium, leading to a perturbated state, called dysbiosis. While probiotic and …
View article: In vitro characterization of amino acid digestibility and fermentative properties of a specific hydrolyzed yeast, and its in vivo effects on growth performance and fecal microbiota in weanling piglets
In vitro characterization of amino acid digestibility and fermentative properties of a specific hydrolyzed yeast, and its in vivo effects on growth performance and fecal microbiota in weanling piglets Open
Weaning is a stressful event that is often accompanied by anorexia, risk of diarrhea, and development of intestinal disorders, making it crucial to provide highly digestible and palatable diets. Novel functional protein sources are being d…
Maternal oral supplementation with Saccharomyces boulardii I-1079 during gestation and early lactation impacts the early growth rate and metabolic profile of newborn puppies Open
Nutritional programming is a manipulation of fetal and neonatal development through maternal feeding. In humans and pigs, maternal yeast supplementation was demonstrated as a promising approach to positively to modulate newborns' health. T…
View article: Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population
Age-Related Changes in Gut Health and Behavioral Biomarkers in a Beagle Dog Population Open
The gut and the gut microbiome communicate with the nervous system through the gut–brain axis via neuroimmune and neuroendocrine mechanisms. Despite existing research, studies exploring this link in aging dogs are limited. This study aims …
View article: Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study
Dietary Inulin Supplementation Modulates Fecal Microbiota and Vaccine Response in Cats—A Double-Blind Randomized Controlled Pilot Study Open
Twenty-six cats were fed either a control or an inulin-supplemented diet (0.6%) for six weeks with measurements of fecal short-chain fatty acids (SCFAs) and microbiota. In the second phase, cats were fed their respective diets for another …
View article: A new combination of a prebiotic and postbiotic mitigates immunosenescence in vaccinated healthy senior dogs
A new combination of a prebiotic and postbiotic mitigates immunosenescence in vaccinated healthy senior dogs Open
Introduction Elderly dogs often suffer from chronic diseases, in part attributed to immunosenescence, characterized by reduced blood CD4+ T cells (helper T cells) and elevation in the CD8+ T cells subset (cytotoxic T cells). Studies conduc…
View article: Effects of an inoculant containing <i>Lentilactobacillus hilgardii</i> (CNCM-I-4785) on the microbiome, fermentation, and aerobic stability of corn silage stored for long term at different incubation temperatures
Effects of an inoculant containing <i>Lentilactobacillus hilgardii</i> (CNCM-I-4785) on the microbiome, fermentation, and aerobic stability of corn silage stored for long term at different incubation temperatures Open
Whole-plant corn untreated (Control) or treated with an inoculant ( Lentilactobacillus buchneri, Lentilactobacillus hilgardii, and Pediococcus pentosaceus, INO) was ensiled for 210 days in mini-silos at constant (MS-C) or variable temperat…
View article: The supplementation of female dogs with live yeast Saccharomyces cerevisiae var. boulardii CNCM I-1079 acts as gut stabilizer at whelping and modulates immunometabolic phenotype of the puppies
The supplementation of female dogs with live yeast Saccharomyces cerevisiae var. boulardii CNCM I-1079 acts as gut stabilizer at whelping and modulates immunometabolic phenotype of the puppies Open
Time around parturition is a stressful period for both bitches and their puppies. The use of probiotics has been proposed, e.g., in pigs, to improve health status of sows, their reproductive performances and in turn, the health and perform…
Large intestinal nutritional and physicochemical parameters from different dog sizes reshape canine microbiota structure and functions <i>in vitro</i> Open
Different dog sizes are associated with variations in large intestinal physiology including gut microbiota, which plays a key role in animal health. This study aims to evaluate, using the CANIM-ARCOL (Canine Mucosal Artificial Colon), the …
Development of a new antibiotic-induced dysbiosis model of the canine colonic microbiota Open
As in humans, antibiotics are widely used in dogs to treat gastrointestinal infections, contributing to the global burden of antimicrobial resistance on both human and animal health. Close contact between pets and their owners can lead to …
Modulation of Zebrafish (Danio rerio) Intestinal Mucosal Barrier Function Fed Different Postbiotics and a Probiotic from Lactobacilli Open
It is generally accepted that microbes play a critical role in maintaining gut barrier function, making them ideal to target in order to mitigate the effects of intestinal diseases such as inflammatory bowel disease with specialist supplem…
View article: Inoculation with Lentilactobacillus buchneri alone or in combination with Lentilactobacillus hilgardii modifies gene expression, fermentation profile, and starch digestibility in high-moisture corn
Inoculation with Lentilactobacillus buchneri alone or in combination with Lentilactobacillus hilgardii modifies gene expression, fermentation profile, and starch digestibility in high-moisture corn Open
Inoculants combining Lentilactobacillus buchneri and Lentilactobacillus hilgardii have been shown to improve the aerobic stability of high-moisture corn (HMC) and whole-plant corn silage, but the mode of action of this co-inoculation remai…
Effect of maternal supplementation with live yeast S. boulardii I-1079 on the gut microbiota of newborn puppies. Open
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View article: Yeast cell wall extracts from Saccharomyces cerevisiae varying in structure and composition differentially shape the innate immunity and mucosal tissue responses of the intestine of zebrafish (Danio rerio)
Yeast cell wall extracts from Saccharomyces cerevisiae varying in structure and composition differentially shape the innate immunity and mucosal tissue responses of the intestine of zebrafish (Danio rerio) Open
With the rising awareness of antimicrobial resistance, the development and use of functional feed additives (FFAs) as an alternative prophylactic approach to improve animal health and performance is increasing. Although the FFAs from yeast…
Composition and evolution of the gut microbiota of growing puppies is impacted by their birth weight Open
Low birth weight puppies present an increased risk of neonatal mortality, morbidity, and some long-term health issues. Yet it has not been investigated if those alterations could be linked to the gut microbiota composition and evolution. 5…
View article: Inoculation with heterofermentative strains <i>Lentilactobacillus buchneri</i> CNCM 40788 and <i>Lentilactobacillus hilgardii</i> CNCM I-4785 either alone or combined improves fermentation and aerobic stability of ensiled triticale (X-triticosecale)
Inoculation with heterofermentative strains <i>Lentilactobacillus buchneri</i> CNCM 40788 and <i>Lentilactobacillus hilgardii</i> CNCM I-4785 either alone or combined improves fermentation and aerobic stability of ensiled triticale (X-triticosecale) Open
Triticale, a small-grain forage, was harvested for an ensiling experiment evaluating different silage inoculants. Fresh material (mean dry matter 404.1 g kg−1) was wilted, chopped, and assigned to one of four treatment groups including wat…
Systèmes digestifs artificiels : applications en nutrition et santé canine Open
Numerous studies have demonstrated the importance of digestion and gut microbiota in the nutrition and health of dogs. Artificial digestive systems represent a relevant alternative to in vivo assays, in accordance with the Euro-pean 3Rs ru…
Gastro-Intestinal Microbiota in Equines and Its Role in Health and Disease: The Black Box Opens Open
Horses are large non-ruminant herbivores and rely on microbial fermentation for energy, with more than half of their maintenance energy requirement coming from microbial fermentation occurring in their enlarged caecum and colon. To achieve…
Gut microbiota development in the growing dog: A dynamic process influenced by maternal, environmental and host factors Open
Microorganisms of the gastrointestinal tract play a crucial role in the health, metabolism and development of their host by modulating vital functions such as digestion, production of key metabolites or stimulation of the immune system. Th…
Effect of live yeast supplementation in sow diet during gestation and lactation on sow and piglet fecal microbiota, health, and performance Open
Feeding probiotics like live yeast Saccharomyces cerevisiae var. boulardii (SB) in pig diets has been suggested to preserve health and reduce antibiotic use during critical periods like weaning. This study was conducted to determine whethe…
View article: Changes to the microbiome of alfalfa during the growing season and after ensiling with Lentilactobacillus buchneri and Lentilactobacillus hilgardii inoculant
Changes to the microbiome of alfalfa during the growing season and after ensiling with Lentilactobacillus buchneri and Lentilactobacillus hilgardii inoculant Open
Aims This study evaluated changes in epiphytic microbial population of alfalfa (Medicago sativa) during the growing season. First cut forage was harvested to study the effects of an inoculant combining two obligate heterofermentative lacti…
From Chihuahua to Saint-Bernard: how did digestion and microbiota evolve with dog sizes Open
Health and well-being of dogs are of paramount importance to their owners. Digestion plays a key role in dog health, involving physicochemical, mechanical and microbial actors. However, decades of breeding selection led to various dog size…
View article: Microbiota succession during aerobic stability of maize silage inoculated with <i>Lentilactobacillus buchneri</i> NCIMB 40788 and <i>Lentilactobacillus hilgardii</i> CNCM‐I‐4785
Microbiota succession during aerobic stability of maize silage inoculated with <i>Lentilactobacillus buchneri</i> NCIMB 40788 and <i>Lentilactobacillus hilgardii</i> CNCM‐I‐4785 Open
Aerobic deterioration of silage following feeding out is responsible for the deterioration of its quality. Inoculation of silage with lactic acid bacteria is one strategy to limit these effects. A trial was performed using whole‐plant corn…
Short-chain fructo-oligosaccharides supplementation to suckling piglets: Assessment of pre- and post-weaning performance and gut health Open
Farmers face difficulties in redeeming their investment in larger litter sizes since this comes with larger litter heterogenicity, lower litter resilience and risk of higher mortality. Dietary oligosaccharides, given to the sow, proved ben…