Emmanuelle Faure-Kumar
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View article: Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection
Brain-wide alterations revealed by spatial transcriptomics and proteomics in COVID-19 infection Open
View article: Brain-wide alterations revealed by spatial transcriptomic and proteomic analyses in COVID-19 infection
Brain-wide alterations revealed by spatial transcriptomic and proteomic analyses in COVID-19 infection Open
Understanding the pathological basis of the neurological symptoms observed following SARS-CoV2 infection is essential to optimizing outcomes and developing therapeutics. To date, small sample sizes and narrow molecular profiling limit the …
View article: Assessment of antibody levels to SARS-CoV-2 in patients with idiopathic inflammatory myopathies receiving treatment with intravenous immunoglobulin
Assessment of antibody levels to SARS-CoV-2 in patients with idiopathic inflammatory myopathies receiving treatment with intravenous immunoglobulin Open
View article: Identification of miR-34-3p as a candidate follicular phase serum marker for endometriosis: a pilot study
Identification of miR-34-3p as a candidate follicular phase serum marker for endometriosis: a pilot study Open
The follicular phase miRNA levels are altered in serum of women with endometriosis and may be useful as reproducible detection biomarkers for early diagnosis of endometriosis. hsa-miR-34-3p is significantly down-regulated in endometriosis,…
View article: Humoral responses to SARS-CoV-2 mRNA vaccines: Role of past infection
Humoral responses to SARS-CoV-2 mRNA vaccines: Role of past infection Open
Two mRNA vaccines (BNT162b2 and mRNA-1273) against severe acute respiratory syndrome-coronavirus 2 (SARS-CoV-2) are globally authorized as a two-dose regimen. Understanding the magnitude and duration of protective immune responses is vital…
View article: Clonally Focused Public and Private T Cells in Resected Brain Tissue From Surgeries to Treat Children With Intractable Seizures
Clonally Focused Public and Private T Cells in Resected Brain Tissue From Surgeries to Treat Children With Intractable Seizures Open
Using a targeted transcriptomics approach, we have analyzed resected brain tissue from a cohort of 53 pediatric epilepsy surgery cases, and have found that there is a spectrum of involvement of both the innate and adaptive immune systems a…
View article: NGS and NanoString Platforms Play Complementary Role in Bedside Advanced Heart Failure Outcome Prediction Test Development
NGS and NanoString Platforms Play Complementary Role in Bedside Advanced Heart Failure Outcome Prediction Test Development Open
View article: Incidence of SARS-CoV-2 infection among asymptomatic frontline health workers in Los Angeles County, California
Incidence of SARS-CoV-2 infection among asymptomatic frontline health workers in Los Angeles County, California Open
Beginning April 8, 2020, we enrolled 1787 frontline heath workers who were asymptomatic for COVID-19 into a longitudinal surveillance study. During that time 4 healthcare workers and 6 first responders tested positive for SARS-CoV-2 by RT-…
View article: MiR130b from Schlafen4 <sup>+</sup> MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer
MiR130b from Schlafen4 <sup>+</sup> MDSCs stimulates epithelial proliferation and correlates with preneoplastic changes prior to gastric cancer Open
The myeloid differentiation factor Schlafen4 (Slfn4) marks a subset of myeloid-derived suppressor cells (MDSCs) in the stomach during Helicobacter -induced spasmolytic polypeptide-expressing metaplasia (SPEM). Objective To identify the gen…
View article: Comparing NGS and NanoString platforms in peripheral blood mononuclear cell transcriptome profiling for advanced heart failure biomarker development
Comparing NGS and NanoString platforms in peripheral blood mononuclear cell transcriptome profiling for advanced heart failure biomarker development Open
In preparation to create a clinical assay that predicts 1-year survival status of advanced heart failure (AdHF) patients before surgical/interventional therapies and to select the appropriate clinical assay platform for the future assay, w…
View article: STEM-24. THERAPEUTIC APPROACH OF STEM CELL CARRYING RETROVIRAL REPLICATING VECTORS IN HUMAN GLIOMA MODEL
STEM-24. THERAPEUTIC APPROACH OF STEM CELL CARRYING RETROVIRAL REPLICATING VECTORS IN HUMAN GLIOMA MODEL Open
Toca 511, an improved retroviral replicating vectors (RRVs) expressing a codon-optimized cytosine deaminase, has shown highly promising evidence of therapeutic benefit in preclinical and clinical studies for gene therapy of glioma. In the …
View article: Overexpressing Long Noncoding RNAs Using Gene-activating CRISPR
Overexpressing Long Noncoding RNAs Using Gene-activating CRISPR Open
Long noncoding RNA (lncRNA) biology is a new and exciting field of research, with the number of publications from this field growing exponentially since 2007. These studies have confirmed that lncRNAs are altered in almost all diseases. Ho…
View article: Factors in the Selection of Surface Disinfectants for Use in a Laboratory Animal Setting.
Factors in the Selection of Surface Disinfectants for Use in a Laboratory Animal Setting. Open
Because surface disinfectants are an important means of pathogen control within laboratory animal facilities, these products must have an appropriate spectrum of antimicrobial activity. However, many other factors must also be considered, …