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View article: Evaluation of the Relationship of HBsAg Serum Plasma Values with HBV DNA and Other Serologic Markers in the Diagnosis of Hepatitis B
Evaluation of the Relationship of HBsAg Serum Plasma Values with HBV DNA and Other Serologic Markers in the Diagnosis of Hepatitis B Open
Objective: Hepatitis B virus (HBV) infections cause a major public health problem worldwide diagnosis and treatment of HBV infection is an important issue. Detection of HBV DNA by polymerase chain reaction (PCR) and demonstration of viral …
View article: Evaluation of Antibiofilm and Antimicrobial Activities of N-heterocyclic Carbene Complexes
Evaluation of Antibiofilm and Antimicrobial Activities of N-heterocyclic Carbene Complexes Open
In recent years, resistance to antimicrobials has become a global problem. Despite the need for new antibiotics with the increase of resistant bacteria, developing new antimicrobials is problematic. Biofilms formed by microorganisms play a…
View article: Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations
Benzimidazol-2-ylidene Silver Complexes: Synthesis, Characterization, Antimicrobial and Antibiofilm Activities, Molecular Docking and Theoretical Investigations Open
Five silver(I) complexes, namely chloro[1-methallyl-3-benzyl)benzimidazol-2-ylidene] silver (6), chloro[1-methallyl-3-(2,3,5,6-tetramethylbenzyl)benzimidazol-2-ylidene]silver (7), chloro[1-methallyl-3-(3,4,5-trimethoxylbenzyl)benzimidazol-…
View article: The Seroprevalence Trend of <i>Helicobacter pylori</i> Infection in a Turkish Tertiary Hospital: A 4-year Retrospective Study
The Seroprevalence Trend of <i>Helicobacter pylori</i> Infection in a Turkish Tertiary Hospital: A 4-year Retrospective Study Open
Objective: Helicobacter pylori (H.pylori) is a Gram-negative microaerophilic bacterium that is associated with diseases such as peptic ulcer, chronic gastritis, gastric MALT lymphoma, and gastric cancer.H. pylori infection is more common i…
View article: FDA-APPROVED MOLECULAR TESTS USED TO DEFINE HUMAN PAPILLOMAVIRUS (HPV) INFECTIONS WHICH CAUSE CERVIX CANCER
FDA-APPROVED MOLECULAR TESTS USED TO DEFINE HUMAN PAPILLOMAVIRUS (HPV) INFECTIONS WHICH CAUSE CERVIX CANCER Open
Human papillomavirus (HPV) is a non-enveloped, commonly sexually transmitted virus with icosahedral symmetry and double-stranded circular DNA. Its genome, which is about 8 kb in size, encodes early genes (E1-8) and two late structural caps…
View article: Antifungal and Antibiofilm Activities of Some Essential Oils Against Candida spp
Antifungal and Antibiofilm Activities of Some Essential Oils Against Candida spp Open
Candida species are commonly encountered strains associated with a wide range of infections. Unlike bacterial pathogens, fungal pathogens treatment is difficult and the development of resistance has been increasing at an alarming rate. In …
View article: Antibiofilm and Antimicrobial Properties of 1-allyl-3-(2-diisopropylaminoethyl) Benzimidazolium Chloride and its Silver(I)-NHC Complex
Antibiofilm and Antimicrobial Properties of 1-allyl-3-(2-diisopropylaminoethyl) Benzimidazolium Chloride and its Silver(I)-NHC Complex Open
Today, the number of antimicrobials used in treatment has decreased, especially due to drug resistance. We need new antimicrobials. Biofilms are an important cause of antimicrobial resistance. In this study, the antimicrobial and antibiofi…
View article: Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes
Antimicrobial, anti-biofilm and cytotoxic properties of methallyl functionalized benzimidazolium-derived Ag(I)-Nheterocyclic carbene complexes Open
Purpose: To investigate the antimicrobial, antibiofilm, and cytotoxicity properties of methallyl substituted benzimidazolium-based, silver-bound N-heterocyclic carbene (Ag(I)-NHC) complexes, with respect to their potential to act as antimi…
View article: Evaluation of the diagnostic performance of the Xpert® MTB/RIF assay in pulmonary and extrapulmonary samples
Evaluation of the diagnostic performance of the Xpert® MTB/RIF assay in pulmonary and extrapulmonary samples Open
A large number of clinical samples were studied with the Xpert MTB/RIF test in our study. It can be a guide in determining the performance of the test under the conditions of our country. Especially in the diagnosis of extrapulmonary TB, t…
View article: Antimicrobial Resistance in Enterococcus faecalis and Enterococcus faecium Bacteria Isolated from Bloodstream Infections: A Single-Center Evaluation
Antimicrobial Resistance in Enterococcus faecalis and Enterococcus faecium Bacteria Isolated from Bloodstream Infections: A Single-Center Evaluation Open
Objective: Enterococci are an important cause of healthcare-related bloodstream infections. The present study aimed to contribute to form empirical treatment models that can be used in the treatment of Enterococcus faecalis and Enterococcu…
View article: Evaluation of In Vitro Antimicrobial Effect of Different Essential Oils
Evaluation of In Vitro Antimicrobial Effect of Different Essential Oils Open
Objective: In this study, it was aimed to investigate the antimicrobial effect of 16 different essential oils by commercially sold, against different standard bacterial strains and one clinical bacterial strain and one standard yeast strai…
View article: Pseudomonas aeruginosa: Evaluation of Antimicrobial Resistance Patterns in Strains Isolated from Blood Culture in a University Hospital
Pseudomonas aeruginosa: Evaluation of Antimicrobial Resistance Patterns in Strains Isolated from Blood Culture in a University Hospital Open
Introduction: The aim of this study was to contribute to the establishment of appropriate empirical treatment protocols by determining antibiotic susceptibility profiles of Pseudomonas aeruginosa strains isolated from bacteremia patients i…
View article: Evaluation of Hepatitis A Seroprevalance and Epidemiologic Data of Patients Applying to A Medical Faculty Hospital
Evaluation of Hepatitis A Seroprevalance and Epidemiologic Data of Patients Applying to A Medical Faculty Hospital Open
Amaç: Bu çalışmada yöremizde hepatit A virüs (HAV) seroprevalansının belirlenmesi ve yıllar içinde prevalansta oluşan değişimin tespit edilerek, çeşitli faktörlerin prevalans üzerindeki etkilerinin değerlendirilmesi amaçlanmıştır.Gereç ve …
View article: Did MALDI-TOF MS Increase Anaerobe Identification in the Microbiology Laboratory? A University Hospital Experience
Did MALDI-TOF MS Increase Anaerobe Identification in the Microbiology Laboratory? A University Hospital Experience Open
Amaç: Bu çalışmada, anaerop kültür istemi ile gelen çeşitli klinik örneklerde tanımlanan tür sayılarının Matriks destekli lazer desorpsiyonu/iyonizasyon süresi-kütle spektrometresi [matriks assisted lazer desorption/ ionization time of fli…
View article: Evaluation of Serological Indicators for Toxoplasma, Rubella Virus and Cytomegalovirus Infections in Pregnant Women Applied to Our Hospital
Evaluation of Serological Indicators for Toxoplasma, Rubella Virus and Cytomegalovirus Infections in Pregnant Women Applied to Our Hospital Open
Objective: Toxoplasma gondii, rubella virus and cytomegalovirus (CMV) are important infectious agents that can be transmitted vertically from mother to baby, and can cause clinical signs in the fetus and the newborn. In our study, it was a…
View article: Epidemiological analysis of Nosocomial Candida infections: Experience of a university hospital
Epidemiological analysis of Nosocomial Candida infections: Experience of a university hospital Open
Objective: A retrospectiveinvestigation was made in a university hospital setting of the distribution ofCandida infections in terms of species, different clinical features ofinfections, risk factors for candidemia caused by these fungi and…
View article: Antimicrobial Efficacy of Chlorhexidine and Licorice Mouthwashes in Children
Antimicrobial Efficacy of Chlorhexidine and Licorice Mouthwashes in Children Open
Objective:The aim of this in vivo study is to evaluate the effectiveness of a simple herbal caries-prevention protocol for reducing salivary Streptococcus mutans levels in children.Materials and Methods:A total of 90 individuals were recru…
View article: Resistance to primary anti-tuberculosis drugs between 2011-2018 in Sivas Cumhuriyet University Faculty of Medicine Hospital
Resistance to primary anti-tuberculosis drugs between 2011-2018 in Sivas Cumhuriyet University Faculty of Medicine Hospital Open
İnsanlık tarihi kadar eski bir hastalık olan tüberküloz hala güncelliğini koruyan önemli bir sağlık problemidir. Etkili antitüberküloz ilaçların keşfiyle tedavisinde önemli
View article: Microbiological Property Evaluation of Natural Essential Oils Used in Green Cosmetic Industry
Microbiological Property Evaluation of Natural Essential Oils Used in Green Cosmetic Industry Open
This study was designed to investigate antimicrobial properties ofnatural essential oils including; citronella, cinnamon, palmarosa, niaouli,clove, lavender, bergamot, lemon, grapefruit, petitgrain, peppermint, tea treeand eucalyptus from …
View article: Antimicrobial Efficacy of Chlorhexidine and Licorice Mouthwashes In Children
Antimicrobial Efficacy of Chlorhexidine and Licorice Mouthwashes In Children Open
Amaç: Bu in vivo çalışmanın amacı, çocuklarda tükürük streptokok mutans (SM) düzeylerini azaltmaya yönelik basit bir bitkisel çürük önleme protokolünün etkinliğini değerlendirmektir
View article: Bactericidal Effect of Different Power Parameters of Potassium-Titanylphosphate Laser on Enterococcus faecalis
Bactericidal Effect of Different Power Parameters of Potassium-Titanylphosphate Laser on Enterococcus faecalis Open
Objective:The objective of this study was to evaluate the antimicrobial activity of different power settings of potassium-titanyl-phosphate (KTP) laser in experimentally infected root canals.Methods:A total of 119 freshly extracted human s…
View article: Biofilm Formation Activities of Isolated Microorganisms from Hospitalized Patients
Biofilm Formation Activities of Isolated Microorganisms from Hospitalized Patients Open
ÖZ GİRİŞ ve AMAÇ: Günümüzde antimikrobiyallere dirençli mikroorganizmaların giderek artması bakteriyel
View article: Radio-protective and antioxidative activities of astaxanthin from newly isolated radio-resistant bacterium Deinococcus sp. strain WMA-LM9
Radio-protective and antioxidative activities of astaxanthin from newly isolated radio-resistant bacterium Deinococcus sp. strain WMA-LM9 Open
A radio-resistant bacterium, designated as strain WMA-LM9, was isolated from desert soil. 16S rRNA gene sequencing indicated that the bacterium belongs to genus Deinococcus with maximum similarity to Deinococcus radiopugnans. Deinococcus s…
View article: “1,3-di(thiophen-2-yl) prop-2-en-1-one” kalkon türevinin antifungal, anti-biyofilm ve anti-kanser aktivitelerinin belirlenmesi
“1,3-di(thiophen-2-yl) prop-2-en-1-one” kalkon türevinin antifungal, anti-biyofilm ve anti-kanser aktivitelerinin belirlenmesi Open
Amaç: Çalışmamızın amacı, literatürde raporedilen beş kalkon bileşiğinin Candida albicansve Candida tropicalis’e karşıpotansiyel antifungal ve antibiyofilmaktivitelerinin belirlenmesidir. Ayrıca antimikrobiyal aktivitesi belirlenen“1,3-di(…
View article: The effect of Vitamin D treatment on thyroid function and the levels of thyroid autoantibodies, TNF-α, IL-6, IL-1β in patients with autoimmune thyroiditis
The effect of Vitamin D treatment on thyroid function and the levels of thyroid autoantibodies, TNF-α, IL-6, IL-1β in patients with autoimmune thyroiditis Open
SUMMARYObjective: To investigate the relationship between autoimmune thyroid disease and vitamin D treatment.Method: Fifty four (54) patients with both vitamin D deficiency and newly diagnosed euthyroid Hashimoto’s thyroiditis (HT) were re…
View article: Anti-biofilm and antimicrobial activity of <i>Mentha pulegium</i> L essential oil against multidrug-resistant <i>Acinetobacter baumannii</i>
Anti-biofilm and antimicrobial activity of <i>Mentha pulegium</i> L essential oil against multidrug-resistant <i>Acinetobacter baumannii</i> Open
Purpose: To investigate the antimicrobial and anti-biofilm activities of essential oil from Mentha pulegieum L. (EOMP) on multi-drug resistant (MDR) isolates of A. baumannii, as well as its phytochemical composition, antioxidant properties…
View article: Anti-biofilm and antimicrobial activity of Mentha pulegium L essential oil against multidrug-resistant Acinetobacter baumannii
Anti-biofilm and antimicrobial activity of Mentha pulegium L essential oil against multidrug-resistant Acinetobacter baumannii Open
Purpose: To develop liposome formulations containing monoclonal antibody anti-HER2 (MabHer2), and Paclitaxel (PTX).Methods: Seven different liposomal systems containing PTX, or MabHer2 or a combination of PTX and MabHer2 were made using li…