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View article: Second Line Therapies After Tyrosine Kinase Inhibitory in Metastatic Renal Cell Carcinoma
Second Line Therapies After Tyrosine Kinase Inhibitory in Metastatic Renal Cell Carcinoma Open
Objective: Controversy exists over the choice of 2nd-line drugs after the progression of 1st-line tyrosine kinase inhibitors (TKIs) for patients unable to receive 1st-line immunotherapy. We compared the efficacy of 2nd-line treatments afte…
View article: The Role of Clinicopathological Features in Tyrosine Kinase Inhibitory Duration in EGFR Mutant Metastatic Non-Small Cell Lung Cancer
The Role of Clinicopathological Features in Tyrosine Kinase Inhibitory Duration in EGFR Mutant Metastatic Non-Small Cell Lung Cancer Open
Background: Epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) are effective treatments for EGFR mutant (EGFRm) metastatic non-small cell lung cancer (mNSCLC). However, the benefit of EGFR-TKIs varies. We aimed to dete…
View article: Assessment of tumor location in adjuvant treatment decision for stage II colon cancer
Assessment of tumor location in adjuvant treatment decision for stage II colon cancer Open
Aims: In stage II colon cancer, the aim is to evaluate the impact of tumor location and other clinicopathological factors on prognosis and survival. Methods: The study included a total of 93 patients diagnosed with stage II colon cancer be…
View article: Efficacy and Tolerability of First-Line Anti-eGFR and Anti-VEGF Therapy in Elderly Patients with Ras-Wild Metastatic Colon Cancer
Efficacy and Tolerability of First-Line Anti-eGFR and Anti-VEGF Therapy in Elderly Patients with Ras-Wild Metastatic Colon Cancer Open
Introduction: Adding targeted agents to chemotherapy for metastatic colorectal cancer increases survival. There have been no clinical trials in older populations comparing the efficacy of the targeted agents. We aimed to compare the effica…
View article: Investigation of the Relationship between COVID-19-Induced Dysfunctional Anxiety and Health Literacy in Oncology Patients
Investigation of the Relationship between COVID-19-Induced Dysfunctional Anxiety and Health Literacy in Oncology Patients Open
Introduction: Improvement of health literacy plays a primary role in improving individual and public health. This study aimed to investigate the relationship between coronavirus disease-2019 (COVID-19)-induced dysfunctional anxiety and hea…
View article: Prognostic significance of prognostic nutritional index and hemoglobin to red cell distribution width ratio in metastatic colorectal cancer patients
Prognostic significance of prognostic nutritional index and hemoglobin to red cell distribution width ratio in metastatic colorectal cancer patients Open
Aims: Malnutrition and systemic inflammation are poor prognostic factors in cancer. Prognostic nutritional index (PNI) and Hemoglobin to red blood cell distribution witdh (HRR) are considered indicators of malnutrition and systemic inflamm…
View article: Impact of prognostic factors on platinum response in extrapulmonary neuroendocrine carcinoma
Impact of prognostic factors on platinum response in extrapulmonary neuroendocrine carcinoma Open
Aim: Extrapulmonary neuroendocrine carcinomas are rare tumors and clinical trials for their treatment are limited.In this study, we aimed to determine the impact of clinicopathological and prognostic factors on platinum response in patient…
View article: Impact of Neutrophil to Lymphocyte Ratio on Pathological Response to Neoadjuvant Chemotherapy in Nonmetastatic Breast Cancer
Impact of Neutrophil to Lymphocyte Ratio on Pathological Response to Neoadjuvant Chemotherapy in Nonmetastatic Breast Cancer Open
B reast cancer is the mostly seen cancer in women [1] Neo- adjuvant chemotherapy (NAC) is the widely accepted treatment strategy for locally advanced and some early stage breast cancer. [2]Neoadjuvant chemotherapy provides some advantages.…
View article: TWO DIFFERENT CHARACTERISTICS AND PROGNOSIS OF GRADE 3 GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS:Erciyes Multidisiplinary Neuroendocrine Tumor (NET) Group Experience
TWO DIFFERENT CHARACTERISTICS AND PROGNOSIS OF GRADE 3 GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS:Erciyes Multidisiplinary Neuroendocrine Tumor (NET) Group Experience Open
Grade 3 gastroenteropancreatic neuroendocrine tumors (GEPNETs) are not a homogenous group. We aimed to determine clinicopathologic, survival and prognostic differences in metastatic grade 3 GEPNETs with the help of ki67 and GA68PET CT/octr…
View article: Is SUVmax of 18F-FDG PET/CT Predictive Factor for Malignancy in Gastrointestinal Tract?
Is SUVmax of 18F-FDG PET/CT Predictive Factor for Malignancy in Gastrointestinal Tract? Open
Background: Increasing use of 18 F-FDG PET/CT in cancer patients, has led to more common detection of 18 F-FDG uptake in the gastrointestinal tract (GIT). Aims: The objective of this study was to assess 18 F-FDG uptake in incidental and kn…
View article: The evaluation of cerebral venous normal anatomy and variations by phase-contrast cranial magnetic resonance venography
The evaluation of cerebral venous normal anatomy and variations by phase-contrast cranial magnetic resonance venography Open
BACKGROUND: The aim of our study was to determine the ability of the phase-contrast-cranial magnetic resonance venography (PC-CMRV) technique to detect cranial anatomy, variations, thrombosis, to reveal the deficits of the technique and to…
View article: Prognostic Significance of Tumor Tissue NeuGcGM3 Ganglioside Expression in Patients Receiving Racotumomab Immunotherapy
Prognostic Significance of Tumor Tissue NeuGcGM3 Ganglioside Expression in Patients Receiving Racotumomab Immunotherapy Open
Expression of N -glycolyl GM3 (NeuGcGM3) ganglioside was detected in the tumor specimens of patients who were on Racotumomab anti-idiotype vaccine maintenance treatment, and prognostic significance as a biomarker was investigated. No stati…
View article: The association between the route of nutrition and serum levels of adipokines in critical illness: a pilot study
The association between the route of nutrition and serum levels of adipokines in critical illness: a pilot study Open
The delivery of EN in critical illness was associated with decreased resistin levels and increased GLP–1 levels. Thus, the route of nutrition may impact the clinical outcome in critical illness due to adipokines.
View article: Evaluation of DNA Damage in Patients with a Neuroendocrine Tumor
Evaluation of DNA Damage in Patients with a Neuroendocrine Tumor Open
Objective: Neuroendocrine tumors develop from the neuroendocrine cells of the endocrine system. As these tumors are extremely slow growing compared with other cancers, they often take years to reach a measurable dimension, thus leading to …