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View article: “Are You Just Looking to ‘Survive’?”: A Qualitative Study of Importance of Oncology Endpoints Beyond Overall Survival in Early-Stage Cancer
“Are You Just Looking to ‘Survive’?”: A Qualitative Study of Importance of Oncology Endpoints Beyond Overall Survival in Early-Stage Cancer Open
Background/Objectives: In early-stage oncology clinical trials, the use of endpoints beyond overall survival (OS), including recurrence-free survival (RFS) or event-free survival (EFS), is becoming more common. To understand whether these …
View article: Transportability of nonlocal real-world evidence and its relevance to health technology assessment: a primer
Transportability of nonlocal real-world evidence and its relevance to health technology assessment: a primer Open
Real-world evidence (RWE) from outside Canada or the UK is sometimes included in submissions to health technology assessments by Canada’s Drug Agency/L'Agence des médicaments du Canada (CDA-AMC) and National Institute for Health and Care E…
View article: PP79 Challenges With Integrating Early-Stage Cancer Trial Endpoints Into Economic Models: Review Of Canadian And International HTA Recommendations
PP79 Challenges With Integrating Early-Stage Cancer Trial Endpoints Into Economic Models: Review Of Canadian And International HTA Recommendations Open
Introduction Therapies for early-stage cancers demonstrate clinical benefit with early endpoints that measure delayed or avoided disease recurrence, and survival benefits take years to confirm. Economic evaluations for health technology as…