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View article: The level of I-FABP and IgA/IgG to beta-lactoglobulin in mothers at risk for gestational diabetes and in their children: association with antibodies to Bifidobacterium adolescentis and Bifidobacterium breve
The level of I-FABP and IgA/IgG to beta-lactoglobulin in mothers at risk for gestational diabetes and in their children: association with antibodies to Bifidobacterium adolescentis and Bifidobacterium breve Open
Background The mechanisms underlying gestational diabetes mellitus (GDM) and their impact on maternal and child immunity remain unclear. We hypothesize that gut microbiome alterations and increased small intestinal permeability contribute …
View article: Quantitative Differences in the Human Intestinal Microbiota Through the Stages of Life: Infants, Children, Adults and the Elderly
Quantitative Differences in the Human Intestinal Microbiota Through the Stages of Life: Infants, Children, Adults and the Elderly Open
The aim of this study was to compare the human intestinal microbiota in different age groups, elucidating the precise stages of life in which the gut microbiota evolves its specific characteristics in terms of composition and diversity, as…
View article: Antibiotic Resistance Spread and Resistance Control Options. Estonian Experience
Antibiotic Resistance Spread and Resistance Control Options. Estonian Experience Open
Antibiotic resistance refers to the ability of microbes to grow in the presence of an antibiotic that would have originally killed or inhibited the growth of these microorganisms. Microorganisms resistant to antibiotics exist in humans, an…
View article: Trends in the prevalence and antibiotic susceptibility of anaerobic Gram-negative bacteria causing clinical infections in Estonia
Trends in the prevalence and antibiotic susceptibility of anaerobic Gram-negative bacteria causing clinical infections in Estonia Open
Objective: The aim of our study was to describe the species distribution and changes in the resistance profile of anaerobic bacteria isolated at Tartu University Hospital. Methods: The data for 2010, 2016 and 2020 were analysed retrospecti…
View article: Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine
Protective antibodies and T cell responses to Omicron variant after the booster dose of BNT162b2 vaccine Open
The high number of mutations in the Omicron variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes its immune escape. We report a longitudinal analysis of 111 vaccinated individuals for their antibody levels up to 6…
View article: Comparative Analysis of Gut Microbiota in Centenarians and Young People: Impact of Eating Habits and Childhood Living Environment
Comparative Analysis of Gut Microbiota in Centenarians and Young People: Impact of Eating Habits and Childhood Living Environment Open
The composition of centenarians’ gut microbiota has consistently been used as a model for healthy aging studies. However, there is an incomplete understanding of how childhood living conditions and eating habits affect the development and …
View article: Protective antibodies and T cell responses to Omicron variant three months after the booster dose of BNT162b2 vaccine
Protective antibodies and T cell responses to Omicron variant three months after the booster dose of BNT162b2 vaccine Open
The high number of mutations in the Omicron variant of SARS-CoV-2 cause its immune escape when compared to the earlier variants of concern (VOC). At least three vaccine doses are required for the induction of Omicron neutralizing antibodie…
View article: Declined antibody responses to COVID-19 mRNA vaccine within first three months
Declined antibody responses to COVID-19 mRNA vaccine within first three months Open
Background Although the SARS-CoV-2 mRNA vaccines have proven high efficacy, limited data exists on the duration of immune responses and their relation to age and side effects. Methods We studied the antibody and memory T cell responses to …
View article: Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical data
Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: Comparison of nine tests in relation to clinical data Open
SARS-CoV-2 antibody tests are available in various formats, detecting different viral target proteins and antibody subclasses. The specificity and sensitivity of SARS-CoV-2 antibody tests are known to vary and very few studies have address…
View article: Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: comparison of nine tests in relation with clinical data
Evaluation of SARS-CoV-2 IgG antibody response in PCR positive patients: comparison of nine tests in relation with clinical data Open
Summary Background High number of SARS-CoV-2 antibody tests are available in different formats, detect different types of antibodies, and use different target proteins. Sensitivity of these tests varies and could be also related to clinica…
View article: NP-005 Implementing medication reconciliation on hospital admission: a multicentre pilot study in Estonia and Finland
NP-005 Implementing medication reconciliation on hospital admission: a multicentre pilot study in Estonia and Finland Open
Background and importance Transitions of care have been determined to be one potential source of errors, especially in relation to medications. WHO has pointed out the need to improve patient safety at transitions for many years as the pro…
View article: Phenotypic and Molecular Epidemiology of ESBL-, AmpC-, and Carbapenemase-Producing Escherichia coli in Northern and Eastern Europe
Phenotypic and Molecular Epidemiology of ESBL-, AmpC-, and Carbapenemase-Producing Escherichia coli in Northern and Eastern Europe Open
Extended-spectrum beta-lactamases (ESBL) and AmpC producing-Escherichia coli have spread worldwide, but data about ESBL-producing-E. coli in the Northern and Eastern regions of Europe is scant. The aim of this study has been to describe th…
View article: Application of Molecular Methods for Carbapenemase Detection
Application of Molecular Methods for Carbapenemase Detection Open
This study has evaluated the correlation between different carbapenemases detection methods on carbapenem non-susceptible Klebsiella pneumoniae strains from Northern and Eastern Europe; 31 institutions in 9 countries participated in the re…
View article: Microbiology of peritonsillar abscess in the South Estonian population
Microbiology of peritonsillar abscess in the South Estonian population Open
PTA patients had mixed anaerobic and aerobic microbiota both in the tissue of the tonsillar fossa and the pus of the peritonsillar space. We demonstrated that the tonsillar fossa specimen is a better material for microbiological analyses, …