Eri Asano‐Inami
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View article: Exploring drug resistance via intercellular crosstalk using spatial transcriptomics in high-grade serous ovarian carcinoma
Exploring drug resistance via intercellular crosstalk using spatial transcriptomics in high-grade serous ovarian carcinoma Open
View article: Differential Proteomics of Large Extracellular Vesicles in Ovarian Cancer
Differential Proteomics of Large Extracellular Vesicles in Ovarian Cancer Open
Diverse extracellular vesicles (EVs) are present in all body fluids; however, knowledge of large EVs (lEVs) remains limited. Molecular EV profiles vary depending on EV size and the physiological circulatory system, even within the same pat…
View article: Proteomic Profiling of Bacterial Extracellular Vesicles for Exploring Ovarian Cancer Biomarkers
Proteomic Profiling of Bacterial Extracellular Vesicles for Exploring Ovarian Cancer Biomarkers Open
Extracellular vesicles (EVs) are present in body fluids and act as disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because o…
View article: Establishment of KGAS, a cell line derived from gastric-type adenocarcinoma of the uterine cervix
Establishment of KGAS, a cell line derived from gastric-type adenocarcinoma of the uterine cervix Open
View article: Overcoming platinum-resistant ovarian cancer targeting the activated JAK-STAT pathways via extracellular vesicles
Overcoming platinum-resistant ovarian cancer targeting the activated JAK-STAT pathways via extracellular vesicles Open
View article: An intratumorally discovered extracellular vesicle-derived biomarker enables ultrasensitive digital quantification in plasma for early detection of non-small cell lung cancer
An intratumorally discovered extracellular vesicle-derived biomarker enables ultrasensitive digital quantification in plasma for early detection of non-small cell lung cancer Open
Background Extracellular vesicle (EV)-based liquid biopsy remains challenging due to the limited specificity and low abundance of EV cargoes. This study aimed to identify cancer-specific molecules from tissue-derived EVs and evaluate their…
View article: Proteomic profiling of bacterial extracellular vesicles for exploring ovarian cancer biomarkers
Proteomic profiling of bacterial extracellular vesicles for exploring ovarian cancer biomarkers Open
Extracellular vesicles (EVs) are present in body fluids and act as disease biomarkers. Emerging evidence has proven that EVs are released not only from mammalian cells but also from bacteria. Ovarian cancer has a dismal prognosis because o…
View article: Elucidation of the role of XBP1 in the progression of complete hydatidiform mole to invasive mole through RNA-seq
Elucidation of the role of XBP1 in the progression of complete hydatidiform mole to invasive mole through RNA-seq Open
RNA-seq identified XBP1 as a key factor in post-molar GTN, suggesting it contributes to the development of post-molar GTN.
View article: Amniotic fluid‐derived small extracellular vesicles for predicting postnatal severe outcome of congenital diaphragmatic hernia
Amniotic fluid‐derived small extracellular vesicles for predicting postnatal severe outcome of congenital diaphragmatic hernia Open
Congenital diaphragmatic hernia (CDH) is a life‐threatening condition with high morbidity and mortality rates. The survival rate of neonates with severe CDH is reportedly only 10%–15%. However, prenatal prediction of severe cases is diffic…
View article: Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology
Small extracellular vesicles in follicular fluids for predicting reproductive outcomes in assisted reproductive technology Open
Background Assisted reproductive technology accounts for an increasing proportion of infertility treatments, and assessments to predict clinical pregnancy outcomes are desired. Extracellular vesicles exist in follicular fluid, and small no…
View article: Elucidation of the Role of Xbp1 in the Progression of Complete Hydatidiform Mole to Invasive Mole Through Rna-Seq
Elucidation of the Role of Xbp1 in the Progression of Complete Hydatidiform Mole to Invasive Mole Through Rna-Seq Open
View article: Leucine zipper protein 1 (<scp>LUZP1</scp>) regulates the constriction velocity of the contractile ring during cytokinesis
Leucine zipper protein 1 (<span>LUZP1</span>) regulates the constriction velocity of the contractile ring during cytokinesis Open
There has been a great deal of research on cell division and its mechanisms; however, its processes still have many unknowns. To find novel proteins that regulate cell division, we performed the screening using siRNAs and/or the expression…
View article: Identifying high-grade serous ovarian carcinoma–specific extracellular vesicles by polyketone-coated nanowires
Identifying high-grade serous ovarian carcinoma–specific extracellular vesicles by polyketone-coated nanowires Open
Cancer cell–derived extracellular vesicles (EVs) have unique protein profiles, making them promising targets as disease biomarkers. High-grade serous ovarian carcinoma (HGSOC) is the deadly subtype of epithelial ovarian cancer, and we aime…
View article: The association of UBAP2L and G3BP1 mediated by small nucleolar RNA is essential for stress granule formation
The association of UBAP2L and G3BP1 mediated by small nucleolar RNA is essential for stress granule formation Open
View article: Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma
Novel therapeutic strategies targeting UCP2 in uterine leiomyosarcoma Open
Uterine leiomyosarcoma (ULMS) is a malignant stromal tumor arising from the myometrium with a poor prognosis and very limited response to current chemotherapy. This study aimed to identify novel targets for ULMS through a three-step screen…
View article: The association of ubiquitin-associated protein 2-like and Ras-GTP-activating protein SH3 domain binding protein 1 mediated by small nucleolar RNA is essential for stress granule formation
The association of ubiquitin-associated protein 2-like and Ras-GTP-activating protein SH3 domain binding protein 1 mediated by small nucleolar RNA is essential for stress granule formation Open
Stress granules (SGs) are dynamic, non-membranous structures composed of non-translating mRNAs and various proteins and play critical roles in cell survival under stressed conditions. Extensive proteomics analyses have been performed to id…
View article: LUZP1 regulates the constriction velocity of the contractile ring during cytokinesis
LUZP1 regulates the constriction velocity of the contractile ring during cytokinesis Open
There has been a great deal of research on cell division and its mechanisms; however, its processes have not yet been entirely elucidated. To find novel proteins that regulate cell division, we performed the screening using siRNAs and/or t…
View article: The association of ubiquitin-associated protein 2-like and Ras-GTP-activating protein SH3 domain binding protein 1 mediated by small nucleolar RNA is essential for stress granule formation
The association of ubiquitin-associated protein 2-like and Ras-GTP-activating protein SH3 domain binding protein 1 mediated by small nucleolar RNA is essential for stress granule formation Open
Stress granules (SGs) are dynamic, non-membranous structures composed of non-translating mRNAs and various proteins and play critical roles in cell survival under stressed conditions. Extensive proteomics analyses have been performed to id…
View article: A regulatory subunit of protein phosphatase 2A, <scp>PPP</scp>2R5E, regulates the abundance of microtubule crosslinking factor 1
A regulatory subunit of protein phosphatase 2A, <span>PPP</span>2R5E, regulates the abundance of microtubule crosslinking factor 1 Open
Dynamic changes in microtubule organization are regulated by numerous microtubule‐associating proteins and their post‐translational modification. Microtubule crosslinking factor 1 ( MTCL 1) is a recently identified protein that regulates m…