Explanipedia

Simple and accessible methods for quantifying isolated mucins for further evaluation Open

Hannah J. McIntire-Ray, Eric A. Rose, Stefanie Krick, Jarrod W. Barnes · 2025

Three warm Jupiters orbiting TOI-6628, TOI-3837, and TOI-5027 and one sub-Saturn orbiting TOI-2328 Open

Marcelo Tala Pinto, A. Jordán, L. Acuña, Matías Jones, Rafael Brahm , et al. · 2025

We report the discovery and characterization of three new transiting giant planets orbiting TOI-6628, TOI-3837, and TOI-5027 and one new warm sub-Saturn orbiting TOI-2328, whose transits events were detected in the light curves of the Tran…

Simple and Accessible Methods for Quantifying Isolated Mucins for Further Evaluation Open

Hannah J. McIntire-Ray, Eric A. Rose, Stefanie Krick, Jarrod W. Barnes · 2025

Randomized Trial of Targeted Transendocardial Mesenchymal Precursor Cell Therapy in Patients With Heart Failure Open

Emerson C. Perin, Kenneth M. Borow, Timothy D. Henry, Farrell O. Mendelsohn, Leslie W. Miller , et al. · 2023

The primary and secondary endpoints of the trial were negative. Positive signals in prespecified, and post hoc exploratory analyses suggest MPCs may improve outcomes, especially in patients with inflammation.

External Support for Saphenous Vein Grafts in Coronary Artery Bypass Surgery Open

Daniel J. Goldstein, John D. Puskas, John H. Alexander, Helena Chang, James S. Gammie , et al. · 2022

ClinicalTrials.gov Identifier: NCT03209609.

CDS-Compare: A Web Application for Machine Learning Assisted Curation of Clinical Order Sets Open

Zackary Falls, Steven H. Brown, Naveed Nazir Shah, Frank LeHouillier, Randeep Badwal , et al. · 2022

Order sets that adhere to disease-specific guidelines have been shown to increase clinician efficiency and patient safety but curating these order sets, particularly for consistency across multiple sites, is difficult and time consuming. W…

Characterizing patterns in police stops by race in Minneapolis from 2016-2021 Open

Tuviere Onookome-Okome, Jonah Gorondensky, Eric A. Rose, Jeffery Sauer, Kristian Lum , et al. · 2022

The murder of George Floyd centered Minneapolis, Minnesota, in conversations on racial injustice in the US. We leverage open data from the Minneapolis Police Department to analyze individual, geographic, and temporal patterns in more than …

The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement Open

Steven R. Messé, Jessica Overbey, Vinod H. Thourani, Alan J. Moskowitz, Annetine C. Gelijns , et al. · 2022

Late-Breaking Science Abstracts and Featured Science Abstracts From the American Heart Association's Scientific Sessions 2021 and Late-Breaking Abstracts in Resuscitation Science From the Resuscitation Science Symposium 2021 Open

Marko Banović, Svetozar Putnik, Martin Pěnička, Gheorghe Doros, Marek Deja , et al. · 2021

Background: There is a class I indication for surgical aortic valve replacement (SAVR) in symptomatic patients with severe aortic stenosis (AS).However, indications for early SAVR in asymptomatic patients with severe AS and normal left ven…

Rationale and design of a randomized trial evaluating an external support device for saphenous vein coronary grafts Open

Emilia Bagiella, John D. Puskas, Alan J. Moskowitz, Annetine C. Gelijns, John H. Alexander , et al. · 2021

Concomitant Tricuspid Repair in Patients with Degenerative Mitral Regurgitation Open

James S. Gammie, Michael Chu, Volkmar Falk, Jessica Overbey, Alan J. Moskowitz , et al. · 2021

Among patients undergoing mitral-valve surgery, those who also received TA had a lower incidence of a primary-end-point event than those who underwent mitral-valve surgery alone at 2 years, a reduction that was driven by less frequent prog…

Risk for non-home discharge following surgery for ischemic mitral valve disease Open

Anuradha Lala, Helena Chang, Xiaoyu Liu, Eric J. Charles, Babatunde A. Yerokun , et al. · 2020

Cost-effectiveness of coronary artery bypass grafting plus mitral valve repair versus coronary artery bypass grafting alone for moderate ischemic mitral regurgitation Open

Bart S. Ferket, Vinod H. Thourani, Pierre Voisine, Samuel F. Hohmann, Helena Chang , et al. · 2019

Pacemaker Implantation After Mitral Valve Surgery With Atrial Fibrillation Ablation Open

Joseph J. DeRose, Donna Mancini, Helena Chang, Michael Argenziano, François Dagenais , et al. · 2019

Intramyocardial Injection of Mesenchymal Precursor Cells and Successful Temporary Weaning From Left Ventricular Assist Device Support in Patients With Advanced Heart Failure Open

Terrence M. Yau, Francis D. Pagani, Donna Mancini, Helena Chang, Anuradha Lala , et al. · 2019

clinicaltrials.gov Identifier: NCT02362646.

Integration of Postcoordination Content into a Clinical Interface Terminology to Support Administrative Coding Open

Eric A. Rose, Steven Rube, Andrew S. Kanter, Matthew Cardwell, Frank Naeymi-Rad · 2019

Background Clinical interface terminologies (CITs) consist of terms designed for clinical documentation and, through mappings to standardized vocabularies, to support secondary uses of patient data, including clinical decision support, qua…

Cost-Effectiveness of Mitral Valve Repair Versus Replacement for Severe Ischemic Mitral Regurgitation Open

Bart S. Ferket, Gorav Ailawadi, Annetine C. Gelijns, Michael A. Acker, Samuel F. Hohmann , et al. · 2018

Background: The CTSN (Cardiothoracic Surgical Trials Network) recently reported no difference in left ventricular end-systolic volume index or in survival at 2 years between patients with severe ischemic mitral regurgitation (MR) randomize…

Biatrial maze procedure versus pulmonary vein isolation for atrial fibrillation during mitral valve surgery: New analytical approaches and end points Open

Eugene H. Blackstone, Helena Chang, Jeevanantham Rajeswaran, Michael K. Parides, Hemant Ishwaran , et al. · 2018

Oral Tecovirimat for the Treatment of Smallpox Open

Douglas W. Grosenbach, Kady M. Honeychurch, Eric A. Rose, Jarasvech Chinsangaram, Annie Frimm , et al. · 2018

On the basis of its efficacy in two animal models and pharmacokinetic and safety data in humans, tecovirimat is being advanced as a therapy for smallpox in accordance with the FDA Animal Rule. (Funded by the National Institutes of Health a…

A Prospective Multi-Institutional Cohort Study of Mediastinal Infections After Cardiac Operations Open

Louis P. Perrault, Katherine Kirkwood, Helena Chang, John C. Mullen, Brian C. Gulack , et al. · 2017

Secondary surgical-site infection after coronary artery bypass grafting: A multi-institutional prospective cohort study Open

Brian C. Gulack, Katherine Kirkwood, Wei Shi, Peter K. Smith, John H. Alexander , et al. · 2017

The Cardiothoracic Surgical Trials Network: Implications for clinical practice Open

Patrick T. O’Gara, Thoralf M. Sundt, Michael A. Acker, Tirone E. David, Robert E. Michler , et al. · 2017

Rate Control versus Rhythm Control for Atrial Fibrillation after Cardiac Surgery Open

A. Marc Gillinov, Emilia Bagiella, Alan J. Moskowitz, Jesse Raiten, Mark A. Groh , et al. · 2016

Strategies for rate control and rhythm control to treat postoperative atrial fibrillation were associated with equal numbers of days of hospitalization, similar complication rates, and similarly low rates of persistent atrial fibrillation …

Two-Year Outcomes of Surgical Treatment of Moderate Ischemic Mitral Regurgitation Open

Robert E. Michler, Peter K. Smith, Michael K. Parides, Gorav Ailawadi, Vinod H. Thourani , et al. · 2016

In a trial comparing coronary-artery bypass grafting (CABG) alone with CABG plus mitral-valve repair in patients with moderate ischemic mitral regurgitation, we found no significant difference in the left ventricular end-systolic volume in…

Two-Year Outcomes of Surgical Treatment of Severe Ischemic Mitral Regurgitation Open

Daniel J. Goldstein, Alan J. Moskowitz, Annetine C. Gelijns, Gorav Ailawadi, Michael K. Parides , et al. · 2015

In patients undergoing mitral-valve repair or replacement for severe ischemic mitral regurgitation, we observed no significant between-group difference in left ventricular reverse remodeling or survival at 2 years. Mitral regurgitation rec…

Surgical Ablation of Atrial Fibrillation during Mitral-Valve Surgery Open

A. Marc Gillinov, Annetine C. Gelijns, Michael K. Parides, Joseph J. DeRose, Alan J. Moskowitz , et al. · 2015

The addition of atrial fibrillation ablation to mitral-valve surgery significantly increased the rate of freedom from atrial fibrillation at 1 year among patients with persistent or long-standing persistent atrial fibrillation, but the ris…

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