Eric Abbate
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View article: Mass-Activated Droplet Sorting for the Selection of Lysine-Producing <i>Escherichia coli</i>
Mass-Activated Droplet Sorting for the Selection of Lysine-Producing <i>Escherichia coli</i> Open
Synthetic biology relies on engineering cells to have desirable properties, such as the production of select chemicals. A bottleneck in engineering methods is often the need to screen and sort variant libraries for potential activity. Drop…
View article: Optimizing the strain engineering process for industrial-scale production of bio-based molecules
Optimizing the strain engineering process for industrial-scale production of bio-based molecules Open
Biomanufacturing could contribute as much as ${\$}$30 trillion to the global economy by 2030. However, the success of the growing bioeconomy depends on our ability to manufacture high-performing strains in a time- and cost-effective manner…
View article: A framework for evaluating edited cell libraries created by massively parallel genome engineering
A framework for evaluating edited cell libraries created by massively parallel genome engineering Open
Genome engineering methodologies are transforming biological research and discovery. Approaches based on CRISPR technology have been broadly adopted and there is growing interest in the generation of massively parallel edited cell librarie…
View article: Dynamic and Functional Profiling of Xylan-Degrading Enzymes in <i>Aspergillus</i> Secretomes Using Activity-Based Probes
Dynamic and Functional Profiling of Xylan-Degrading Enzymes in <i>Aspergillus</i> Secretomes Using Activity-Based Probes Open
Plant polysaccharides represent a virtually unlimited feedstock for the generation of biofuels and other commodities. However, the extraordinary recalcitrance of plant polysaccharides toward breakdown necessitates a continued search for en…