Eric Adéhossi
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View article: Respiratory Syncytial Virus Epidemiology During and After Covid‐19 Pandemic in Africa: Systematic Review and Meta‐Analysis
Respiratory Syncytial Virus Epidemiology During and After Covid‐19 Pandemic in Africa: Systematic Review and Meta‐Analysis Open
Background and Aims Respiratory syncytial virus (RSV) is a major agent of acute respiratory infections in children and the elderly. RSV epidemiology has been changed by the since Covid‐19 pandemic and this review aimed to assess the extent…
View article: Using linezolid as a substitute for the injectable in case of ototoxicity is safer and as effective as all-oral treatment for rifampicin-resistant TB
Using linezolid as a substitute for the injectable in case of ototoxicity is safer and as effective as all-oral treatment for rifampicin-resistant TB Open
BACKGROUNDWHO recommends all-oral bedaquiline (BDQ) and linezolid (LZD)-containing regimens for rifampicin-resistant TB (RR-TB). In Niger, high cure rates were achieved using an adaptive short treatment regimen (aSTR) with a second-line in…
View article: Factors associated with severe acute malnutrition among children aged 6 to 24 months at the Regional Hospital Center (CHR) of Maradi: a case-control study
Factors associated with severe acute malnutrition among children aged 6 to 24 months at the Regional Hospital Center (CHR) of Maradi: a case-control study Open
Background: Severe acute malnutrition (SAM) remains a major public health challenge in Niger, especially in the Maradi region where prevalence exceeds WHO alert thresholds. Objective: To identify factors associated of SAM among children ag…
View article: First detection and entomological characterisation of invasive malaria vector Anopheles stephensi in sympatry with other vectors in Gayi Southern Niger Republic
First detection and entomological characterisation of invasive malaria vector Anopheles stephensi in sympatry with other vectors in Gayi Southern Niger Republic Open
Anopheles stephensi, an invasive vector is aggressively expanding its geographic range across Africa, posing significant threat to malaria control. Surveillance of its spread is crucial for mitigating its impact on malaria transmission. He…
View article: Prevalence of Protozoan in HIV/AIDS Patients with Gastrointestinal Symptoms in Zinder National Hospital, Niger Republic
Prevalence of Protozoan in HIV/AIDS Patients with Gastrointestinal Symptoms in Zinder National Hospital, Niger Republic Open
Background Intestinal parasitic infections constitute one of the stubborn public health issues, particularly in low- and middle-income countries. This study aimed to investigate the prevalence and diversity of intestinal parasites among pa…
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Graphical abstract
View article: Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial
Evaluation of hydroxychloroquine or chloroquine for the prevention of COVID-19 (COPCOV): A double-blind, randomised, placebo-controlled trial Open
Background Hydroxychloroquine (HCQ) has proved ineffective in treating patients hospitalised with Coronavirus Disease 2019 (COVID-19), but uncertainty remains over its safety and efficacy in chemoprevention. Previous chemoprevention random…
View article: Antimicrobial use in hospitalized patients: a point prevalence survey across four tertiary hospitals in Niger
Antimicrobial use in hospitalized patients: a point prevalence survey across four tertiary hospitals in Niger Open
Background Antimicrobial resistance (AMR) is a global threat to public health. Misuse or overuse of antimicrobials contributes to the emergence of AMR. Data on antimicrobial prescribing represent the cornerstone for guiding antimicrobial s…
View article: Real-Time Metagenomics Next-Generation Sequencing for Diagnosing Polymicrobial Meningoencephalitis in Niger: A Case Report
Real-Time Metagenomics Next-Generation Sequencing for Diagnosing Polymicrobial Meningoencephalitis in Niger: A Case Report Open
Background: Real-time metagenomics next-generation sequencing (RT-mNGS) has emerged as a high-throughput technique for directly identifying pathogen genomes from clinical samples. This study aimed to document a case of nonroutinely diagnos…
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Background. Macrolide-induced resistance to clindamycin is a well-described mechanism leading to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin resistance in Gram-positive cocci in a …
View article: Therapeutic efficacy and tolerability of artemether–lumefantrine for uncomplicated Plasmodium falciparum malaria in Niger, 2020
Therapeutic efficacy and tolerability of artemether–lumefantrine for uncomplicated Plasmodium falciparum malaria in Niger, 2020 Open
Background Monitoring therapeutic efficacy is important to ensure the efficacy of artemisinin-based combination therapy (ACT) for malaria. The current first-line treatment for uncomplicated malaria recommended by the National Malaria Contr…
View article: What is the materno-fetal prognosis of adrenal insufficiency and pregnancy in low-resource setting? a case report
What is the materno-fetal prognosis of adrenal insufficiency and pregnancy in low-resource setting? a case report Open
Introduction and importance: Adrenal insufficiency is a rare chronic disease with a prevalence of 39 to 60 cases per million peoples in Europe. However, the prevalence is higher in sub-saharian Africa. The occurrence of pregnancy in adrena…
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in a tertiary hospital in Niger Republic Open
Background. Macrolide-induced resistance to clindamycin is a well-described mechanism leading to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin resistance in Gram-positive cocci in a …
View article: Urinary Infections in the Elderly: Socio-Demographic, Clinical and Paraclinical Aspect about a Multicenter Study in Niamey (Niger)
Urinary Infections in the Elderly: Socio-Demographic, Clinical and Paraclinical Aspect about a Multicenter Study in Niamey (Niger) Open
Introduction: Urinary infections in the elderly are common with atypical clinical signs that can impair quality of life. The objective of the study was to describe the sociodemographic, clinical and paraclinical aspects of urinary infectio…
View article: Therapeutic Efficacy and Tolerability of Artemether-lumefantrine for Uncomplicated Plasmodium Falciparum Malaria in Niger, 2020
Therapeutic Efficacy and Tolerability of Artemether-lumefantrine for Uncomplicated Plasmodium Falciparum Malaria in Niger, 2020 Open
Background Monitoring therapeutic efficacy is important to ensure the efficacy of artemisinin-based combination therapies (ACTs) for malaria. The current first-line treatment for uncomplicated malaria recommended by the National Malaria Co…
View article: Extension of Chemoprevention of Seasonal Malaria to Five Cycles and to Children from the Age of 6 to 9 Years in Africa: Analysis of Its Acceptability, Feasibility, Cost and Impact A Systematic Review
Extension of Chemoprevention of Seasonal Malaria to Five Cycles and to Children from the Age of 6 to 9 Years in Africa: Analysis of Its Acceptability, Feasibility, Cost and Impact A Systematic Review Open
Introduction: Seasonal Malaria Chemoprevention (SMC) aims at preventing malaria in children during the high transmission season. It has been recommended by the WHO since 2013 for children from the age of 3-59 months. However, despite the i…
View article: Reviewer response for version 1
Reviewer response for version 1 Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Surveillance de la paralysie flasque aiguë au Niger de 1998 à 2021
Surveillance de la paralysie flasque aiguë au Niger de 1998 à 2021 Open
Acute flaccid paralysis surveillance in Niger from 1998 to 2021 Introduction. Acute flaccid paralysis (AFP) caused by acute anterior poliomyelitis (AAP) remains endemic in some Asian and African countries, particularly Niger. Performance i…
View article: Reviewer response for version 1
Reviewer response for version 1 Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Inducible clindamycin resistance among clinical Gram-positive cocci in Niger Republic
Inducible clindamycin resistance among clinical Gram-positive cocci in Niger Republic Open
Background Macrolide-induced resistance to clindamycin is a well-described mechanism leading to the misuse of clindamycin and hence to treatment failure. Herein, we determined the frequency and associated factors of inducible clindamycin r…
View article: Fractional dosing to improve vaccination coverage, vaccine hesitancy, and cost-effectiveness in Africa: a systematic review
Fractional dosing to improve vaccination coverage, vaccine hesitancy, and cost-effectiveness in Africa: a systematic review Open
Background The major challenges of vaccination programs are notably coverage in the target population, vaccine hesitancy, and cost-effectiveness. A vaccination strategy with fractional doses is a dose-saving strategy to address current vac…
View article: Metagenomic Direct Diagnosis of Polymicrobial Community-Acquired Meningoencephalitis in Niger: A Case Report
Metagenomic Direct Diagnosis of Polymicrobial Community-Acquired Meningoencephalitis in Niger: A Case Report Open
Current routine diagnosis of a life-threatening central nervous system (CNS) infections is based on commercial multiplex real-time PCR (RT-PCR) and in-vitro culture investigations, targeting a limited number of pathogens, which requires im…
View article: Evaluation of the Knowledge, Attitudes and Practices of the Staff of private Pharmacies in the city of Niamey and their clients on the management of Malaria in 2021
Evaluation of the Knowledge, Attitudes and Practices of the Staff of private Pharmacies in the city of Niamey and their clients on the management of Malaria in 2021 Open
Objective: Malaria is a major public health problem in Niger. It accounts for 28% of all illnesses in the country and 50% of all death records. The objective of our study was to analyze the role played by private pharmacies in the manageme…