Eric D. Adams
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View article: Sex‐specific associations between AD genotype and the microbiome of human amyloid beta knock‐in (hAβ‐KI) mice
Sex‐specific associations between AD genotype and the microbiome of human amyloid beta knock‐in (hAβ‐KI) mice Open
INTRODUCTION Emerging evidence links changes in the gut microbiome to late‐onset Alzheimer's disease (LOAD), necessitating examination of AD mouse models with consideration of the microbiome. METHODS We used shotgun metagenomics and untarg…
View article: Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease
Longitudinal Analysis of the Microbiome and Metabolome in the 5xfAD Mouse Model of Alzheimer’s Disease Open
Microorganisms residing within the gastrointestinal tract are implicated in the onset and progression of Alzheimer’s disease (AD) through the mediation of inflammation, exchange of small-molecules across the blood-brain barrier, and stimul…
View article: Longitudinal analysis of the gut microbiome in the 5xfAD mouse model of Alzheimer’s disease
Longitudinal analysis of the gut microbiome in the 5xfAD mouse model of Alzheimer’s disease Open
INTRODUCTION Microbial exposures impact Alzheimer’s disease (AD), and a baseline understanding of AD model microbiomes is vital for improving model efficacy. We describe the evaluation of the microbiome and metabolome in longitudinal sampl…
View article: RNA Viromics of Southern California Wastewater and Detection of SARS-CoV-2 Single-Nucleotide Variants
RNA Viromics of Southern California Wastewater and Detection of SARS-CoV-2 Single-Nucleotide Variants Open
Wastewater-based epidemiology (WBE) can detect pathogens across sewersheds, which represents the collective waste of human populations. As there is a wide diversity of RNA viruses in wastewater, monitoring the presence of these viruses is …
View article: RNA viromics of Southern California wastewater and detection of SARS-CoV-2 single nucleotide variants
RNA viromics of Southern California wastewater and detection of SARS-CoV-2 single nucleotide variants Open
Municipal wastewater provides an integrated sample of a diversity of human-associated microbes across a sewershed, including viruses. Wastewater-based epidemiology (WBE) is a promising strategy to detect pathogens and may serve as an early…
View article: Comparing Fecal, Saliva and Chicha Microbiomes Between Mothers and Children in an Indigenous Ecuadorian Cohort
Comparing Fecal, Saliva and Chicha Microbiomes Between Mothers and Children in an Indigenous Ecuadorian Cohort Open
Recent research has elucidated many factors which play a role in the development and composition of human microbiomes. In this study we briefly examine the microbiomes of saliva and fecal samples from 71 indigenous individuals, and chicha …
View article: Low Volume Methodology for Nextera DNA Flex Library Prep Kit (96 Samples) v1
Low Volume Methodology for Nextera DNA Flex Library Prep Kit (96 Samples) v1 Open
This protocol presents a low volume methodology for the Nextera DNA Flex Library Prep Kit (96 Samples). This method increases the number of sequencing libraries which can be generated using each kit from 384 samples (4 x 96-wells) to 864 s…