Eric Dinnerstein
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Alzheimer disease combination therapy: learning from the HIV drug development cascade Open
Background Once an incurable deadly disease of urgent public health concern, human immunodeficiency virus (HIV) infection has now evolved into a chronic condition largely manageable with combination therapy as the treatment standard. In co…
View article: Donanemab in Early Symptomatic Alzheimer Disease
Donanemab in Early Symptomatic Alzheimer Disease Open
Importance There are limited efficacious treatments for Alzheimer disease. Objective To assess efficacy and adverse events of donanemab, an antibody designed to clear brain amyloid plaque. Design, Setting, and Participants Multicenter (277…