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View article: Acute metabolic responses to high‐intensity interval training in men with overweight or obesity: Does the exercise modality matter?
Acute metabolic responses to high‐intensity interval training in men with overweight or obesity: Does the exercise modality matter? Open
This study investigated the acute effects of two isoenergetic high‐intensity interval exercise (HIIE) sessions, running (HIIE‐RUN) and cycling (HIIE‐BIKE), on post‐exercise oxygen consumption (), carbon dioxide production (), substrate oxi…
View article: Sexual health indicators among young adults living with perinatally-acquired HIV in france, a gender-stratified comparison with their peers in the general population
Sexual health indicators among young adults living with perinatally-acquired HIV in france, a gender-stratified comparison with their peers in the general population Open
The COVERTE study received approval from the CPP III (n°2738). For the BS surveys, the CNIL approved each survey (n°915589).
View article: Pediatric refractory chronic immune thrombocytopenia: Identification, patients' characteristics, and outcome
Pediatric refractory chronic immune thrombocytopenia: Identification, patients' characteristics, and outcome Open
Refractory chronic immune thrombocytopenia (r‐cITP) is one of the most challenging situations in chronic immune thrombocytopenia (cITP). Pediatric r‐cITP is inconsistently defined in literature, contributing to the scarcity of data. Moreov…
View article: Effects of a Cycling versus Running HIIT Program on Fat Mass Loss and Gut Microbiota Composition in Men with Overweight/Obesity
Effects of a Cycling versus Running HIIT Program on Fat Mass Loss and Gut Microbiota Composition in Men with Overweight/Obesity Open
Purpose High-intensity interval training (HIIT) can efficiently decrease total and (intra-)abdominal fat mass (FM); however, the effects of running versus cycling HIIT programs on FM reduction have not been compared yet. In addition, the l…
View article: Impact of age at diagnosis, sex, and immunopathological manifestations in 886 patients with pediatric chronic immune thrombocytopenia
Impact of age at diagnosis, sex, and immunopathological manifestations in 886 patients with pediatric chronic immune thrombocytopenia Open
Pediatric chronic immune thrombocytopenia (cITP) is a heterogeneous condition in terms of bleeding severity, second‐line treatment use, association with clinical and/or biological immunopathological manifestations (IMs), and progression to…
View article: Isocaloric Diets with Different Protein-Carbohydrate Ratios: The Effect on Sleep, Melatonin Secretion and Subsequent Nutritional Response in Healthy Young Men
Isocaloric Diets with Different Protein-Carbohydrate Ratios: The Effect on Sleep, Melatonin Secretion and Subsequent Nutritional Response in Healthy Young Men Open
This study aimed to determine the short-term effect of two isocaloric diets differing in the ratio of protein–carbohydrate on melatonin levels, sleep, and subsequent dietary intake and physical activity in healthy young men. Twenty-four he…
View article: Adherence to a Physical Activity Program Depends on Individual Fitness Purpose in Older Persons
Adherence to a Physical Activity Program Depends on Individual Fitness Purpose in Older Persons Open
International audience
View article: Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias
Determinants of long-term outcomes of splenectomy in pediatric autoimmune cytopenias Open
Splenectomy is effective in ∼70% to 80% of pediatric chronic immune thrombocytopenia (cITP) cases, and few data exist about it in autoimmune hemolytic anemia (AIHA) and Evans syndrome (ES). Because of the irreversibility of the procedure a…
View article: Eucaloric Balanced Diet Improved Objective Sleep in Adolescents with Obesity
Eucaloric Balanced Diet Improved Objective Sleep in Adolescents with Obesity Open
Background: A better understanding of the influence of energy balance on sleep in adolescents, particularly those with obesity, could help develop strategies to optimize sleep in these populations. The purpose of this study was to investig…
View article: Sleep pattern and staging in elite adolescent rugby players during the in‐season competitive phase compared to an age matched non‐athlete population
Sleep pattern and staging in elite adolescent rugby players during the in‐season competitive phase compared to an age matched non‐athlete population Open
Young athletes must contend with the constraints of elite sports on top of school commitments and the physiological processes associated with adolescence. This study assessed week and weekend sleep and schedule of activities in elite adole…
View article: Long term follow-up of pediatric-onset Evans syndrome: broad immunopathological manifestations and high treatment burden
Long term follow-up of pediatric-onset Evans syndrome: broad immunopathological manifestations and high treatment burden Open
Pediatric-onset Evans syndrome (pES) is defined by both immune thrombocytopenic purpura (ITP) and autoimmune hemolytic anemia (AIHA) before the age of 18 years. There have been no comprehensive long-term studies of this rare disease, which…
View article: Large-Scale Assessment of Health-Related Physical Fitness in French Older Adults: Feasibility and Validity
Large-Scale Assessment of Health-Related Physical Fitness in French Older Adults: Feasibility and Validity Open
Objectives: This study aims to assess the validity, internal consistency, implementation, and feasibility of a sequence of tests, the Vitality Test Battery, designed to measure physical fitness, at a large scale in French older adults. Met…
View article: Randomized Double-Blind Controlled Trial on the Effect of Proteins with Different Tryptophan/Large Neutral Amino Acid Ratios on Sleep in Adolescents: The PROTMORPHEUS Study
Randomized Double-Blind Controlled Trial on the Effect of Proteins with Different Tryptophan/Large Neutral Amino Acid Ratios on Sleep in Adolescents: The PROTMORPHEUS Study Open
Disturbed sleep is common in adolescents. Ingested nutrients help regulate the internal clock and influence sleep quality. The purpose of this clinical trial is to assess the effect of protein tryptophan (Trp)/large neutral amino acids (LN…
View article: Muscle function and architecture in children with juvenile idiopathic arthritis
Muscle function and architecture in children with juvenile idiopathic arthritis Open
Aim To assess muscle function and functional abilities in children with juvenile idiopathic arthritis (JIA). Methods Fourteen children with JIA and 14 healthy controls matched for age and sex were included. Muscle characteristics, both str…
View article: Childhood Leukemia Survivors and Metabolic Response to Exercise: A Pilot Controlled Study
Childhood Leukemia Survivors and Metabolic Response to Exercise: A Pilot Controlled Study Open
Background: Leukemia is the most common cancer in pediatrics, with many late effects such as higher risk of dyslipidemia, insulin resistance, obesity, and metabolic syndrome. The objective of this work was to investigate substrate oxidatio…
View article: Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements
Efficacy of tyrosine kinase inhibitors in Ph-like acute lymphoblastic leukemia harboring ABL-class rearrangements Open
Tanasi et al present a prospective strategy for identifying patients with Philadelphia-like acute lymphoblastic leukemia, demonstrating the efficacy of early introduction of tyrosine kinase inhibitors in improving outcomes.
View article: TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis
TNF blockade contributes to restore lipid oxidation during exercise in children with juvenile idiopathic arthritis Open
In ClinicalTrials.gov, reference number NCT02977416 , registered on 30 November 2016.
View article: Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes
Pediatric Evans syndrome is associated with a high frequency of potentially damaging variants in immune genes Open
Evans syndrome (ES) is a rare severe autoimmune disorder characterized by the combination of autoimmune hemolytic anemia and immune thrombocytopenia. In most cases, the underlying cause is unknown. We sought to identify genetic defects in …
View article: Measuring levels of muscle fatigue in spastic cerebral palsy
Measuring levels of muscle fatigue in spastic cerebral palsy Open
This commentary is on the original article by Eken et al. on pages 212–218 of this issue.