Eric Dumas de la Roque
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View article: Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model
Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model Open
Administration of pulmonary surfactant is crucial for the treatment of respiratory distress syndrome (RDS) in preterm infants. The aim of this study is to evaluate the potential of Curosurf atomization via the Endosurf device, a recently d…
View article: Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model
Characterization of atomization and delivery efficiency of exogenous surfactant in preterm infant lungs using an ex vivo respiratory model Open
Administration of pulmonary surfactant is crucial for the treatment of respiratory distress syndrome (RDS) in preterm infants. The aim of this study is to evaluate the potential of Curosurf atomization via the Endosurf device, a recently d…
View article: MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model
MR Imaging of Pulmonary Surfactant Distribution in a Preclinical Neonatal Lung Model Open
The administration of exogenous surfactant is essential for many premature infants to compensate for pulmonary immaturity and the absence of endogenous surfactant at birth. Exogenous surfactant delivery techniques are continually being ref…
View article: New insights into exogenous surfactant delivery to preterm infant lungs: characterization and efficiency of atomization using an ex vivo respiratory model
New insights into exogenous surfactant delivery to preterm infant lungs: characterization and efficiency of atomization using an ex vivo respiratory model Open
Introduction: The administration of pulmonary surfactant is crucial for the treatment of respiratory distress syndrome (RDS) in preterm infants. The aim of this study is to evaluate the potential of Curosurf ® atomization via the Endosurf …
View article: Nasal high-frequency percussive ventilation versus nasal continuous positive airway pressure in term and preterm neonates exhibiting respiratory distress: a randomized controlled trial (TONIPEP; NCT 02030691)
Nasal high-frequency percussive ventilation versus nasal continuous positive airway pressure in term and preterm neonates exhibiting respiratory distress: a randomized controlled trial (TONIPEP; NCT 02030691) Open
Objective To determine whether the use of nasal, high-frequency percussive ventilation (nHFPV) to manage neonatal respiratory distress decreases the regional cerebral oxygen saturation (rScO 2 ) below that afforded by nasal continuous posi…
View article: Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease
Connexin-43 is a promising target for pulmonary hypertension due to hypoxaemic lung disease Open
The mechanisms underlying pulmonary hypertension (PH) are complex and multifactorial, and involve different cell types that are interconnected through gap junctional channels. Although connexin (Cx)-43 is the most abundant gap junction pro…
View article: Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling
Altered vasoreactivity in neonatal rats with pulmonary hypertension associated with bronchopulmonary dysplasia: Implication of both eNOS phosphorylation and calcium signaling Open
Bronchopulmonary dysplasia (BPD) consists of an arrest of pulmonary vascular and alveolar growth, with persistent hypoplasia of the pulmonary microvasculature and alveolar simplification. In 25 to 40% of the cases, BPD is complicated by pu…