Eric Eckbo
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View article: Mucormycosis in a Pediatric Oncology Population - Review of Cases and the Literature
Mucormycosis in a Pediatric Oncology Population - Review of Cases and the Literature Open
Background : Mucormycosis is the third most common invasive fungal infection in children and primarily affects those with cancer. Incidence rates and contemporary survival statistics are needed in view of current oncology treatments, molec…
View article: The science behind the nose: correlating volatile organic compound characterisation with canine biodetection of COVID-19
The science behind the nose: correlating volatile organic compound characterisation with canine biodetection of COVID-19 Open
Background The SARS-CoV-2 pandemic stimulated the advancement and research in the field of canine scent detection of COVID-19 and volatile organic compound (VOC) breath sampling. It remains unclear which VOCs are associated with positive c…
View article: Severe hypercalcemia as a result of disseminated Candida krusei infection
Severe hypercalcemia as a result of disseminated Candida krusei infection Open
Candida krusei disseminated infection is a rare complication of protracted neutropenia. Herein, we report a case of a 31-year-old male with relapsed acute myeloid leukemia who developed Candida krusei fungemia with cutaneous, ocular, splen…
View article: Quick versus Quantitative: Evaluation of Two Commercial Real-Time PCR Assays for the Detection of Pneumocystis jirovecii from Bronchoalveolar Lavage Fluids
Quick versus Quantitative: Evaluation of Two Commercial Real-Time PCR Assays for the Detection of Pneumocystis jirovecii from Bronchoalveolar Lavage Fluids Open
Pneumonia, caused by the opportunistic fungus Pneumocystis jirovecii , poses a significant risk for immunocompromised individuals. Laboratory testing for P. jirovecii is progressively shifting toward the use of molecular tests such as real…
View article: In search of COVID-19: The ability of biodetection canines to detect COVID-19 odours from clinical samples
In search of COVID-19: The ability of biodetection canines to detect COVID-19 odours from clinical samples Open
BACKGROUND: COVID-19 continues to be a public health concern and the demand for fast and reliable screening tests remains. SARS-CoV-2 infection in humans generates a specific volatile organic compound signature; this ‘volatilome’ could be …
View article: Automated 16S Sequencing Using an R-Based Analysis Module for Bacterial Identification
Automated 16S Sequencing Using an R-Based Analysis Module for Bacterial Identification Open
Sanger sequencing of the 16S rRNA gene is widely used as a diagnostic tool for bacterial identification, especially in cases where routine diagnostic methods fail to provide an identification, for organisms that are difficult to culture, o…
View article: Lymphogranuloma venereum
Lymphogranuloma venereum Open
The L1, L2, and L3 strains are more invasive than those causing most anogenital infections.[1][1]–[4][2] Before 2004, LGV was rare in Canada, but has since become endemic. Between 2013 and 2020, 2052 C. trachomatis isolates forwarded to th…
View article: Needle in a haystack: Looking for tuberculosis in a low-incidence setting
Needle in a haystack: Looking for tuberculosis in a low-incidence setting Open
Background: Canada is a low-incidence country for tuberculosis (TB). The BC Public Health Laboratory diagnostic algorithm for pulmonary TB includes acid fast bacilli (AFB) smear and mycobacterial culture of all submitted sputa. TB nucleic …
View article: Relapsing fever in a traveller returning from Senegal
Relapsing fever in a traveller returning from Senegal Open
KEY POINTS
\n• A broad differential should be maintained in the returning
\ntraveller with fever, and a detailed travel, social and exposure
\nhistory elicited to help guide appropriate diagnostics.
\n• Spirochetes seen in routine peripher…
View article: An unusual case of abdominal pain and splenomegaly in a paediatric patient
An unusual case of abdominal pain and splenomegaly in a paediatric patient Open
Fusobacterium species are members of the oral microbiota and have been found to cause a wide spectrum of opportunistic infections. We describe the case of a previously healthy teenager with a large splenic abscess secondary to Fusobacteriu…