Eric C. Eichenwald
YOU?
Author Swipe
View article: Data harmonization framework for neonatal hypoxic-ischemic encephalopathy studies
Data harmonization framework for neonatal hypoxic-ischemic encephalopathy studies Open
Objectives To develop a data harmonization framework for neonatal hypoxic-ischemic encephalopathy (HIE) studies and demonstrate its suitability for prognostic biomarker development. Materials and Methods Variables were first categorized by…
View article: What is the Role of Caffeine in the Management of Preterm Infants?
What is the Role of Caffeine in the Management of Preterm Infants? Open
Purpose of Review To describe how clinical practice around caffeine therapy for apnea of prematurity has shifted in response to emerging data, with particular emphasis on changes in initiation timing, dosing strategies, and treatment durat…
View article: Late-Onset Sepsis Among Extremely Preterm Infants During the COVID-19 Pandemic
Late-Onset Sepsis Among Extremely Preterm Infants During the COVID-19 Pandemic Open
OBJECTIVES To compare incidence of late-onset sepsis (LOS) among extremely preterm infants before and during the COVID-19 pandemic. METHODS Multicenter cohort study of infants with birthweight 401 to 1000 g or gestational age 22 to 28 week…
View article: Phototherapy to Prevent Severe Neonatal Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation: Technical Report
Phototherapy to Prevent Severe Neonatal Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation: Technical Report Open
OBJECTIVE To summarize the principles and application of phototherapy consistent with the current 2022 American Academy of Pediatrics “Clinical Practice Guideline Revision for the Management of Hyperbilirubinemia in the Newborn Infant 35 o…
View article: Identification and Management of Ankyloglossia and Its Effect on Breastfeeding in Infants: Clinical Report
Identification and Management of Ankyloglossia and Its Effect on Breastfeeding in Infants: Clinical Report Open
Ankyloglossia refers to a congenitally tight lingual frenulum that limits the motion of the tongue. Whether the release of a tight lingual frenulum in neonates improves breastfeeding is not clear. Because many of the symptoms of ankyloglos…
View article: Acetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity
Acetaminophen for Patent Ductus Arteriosus and Risk of Mortality and Pulmonary Morbidity Open
OBJECTIVE Emerging data indicate that acetaminophen may adversely affect lung health. We examined whether acetaminophen compared with cyclooxygenase (COX) inhibitor alone for patent ductus arteriosus (PDA) is associated with mortality or r…
View article: Primary Care Framework to Monitor Preterm Infants for Neurodevelopmental Outcomes in Early Childhood
Primary Care Framework to Monitor Preterm Infants for Neurodevelopmental Outcomes in Early Childhood Open
To support decision-making in the primary care medical home, this clinical report links preterm birth and perinatal complications to early childhood developmental disability risks. It consolidates extensive contemporary outcome research fr…
View article: Assessment of Corticosteroid Therapy and Death or Disability According to Pretreatment Risk of Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants
Assessment of Corticosteroid Therapy and Death or Disability According to Pretreatment Risk of Death or Bronchopulmonary Dysplasia in Extremely Preterm Infants Open
Importance Meta-analyses suggest that corticosteroids may be associated with increased survival without cerebral palsy in infants at high risk of bronchopulmonary dysplasia (BPD) but are associated with adverse neurologic outcomes in low-r…
View article: Online clinical tool to estimate risk of bronchopulmonary dysplasia in extremely preterm infants
Online clinical tool to estimate risk of bronchopulmonary dysplasia in extremely preterm infants Open
Objective Develop an online estimator that accurately predicts bronchopulmonary dysplasia (BPD) severity or death using readily-available demographic and clinical data. Design Retrospective analysis of data entered into a prospective regis…
View article: Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update
Strategies to prevent ventilator-associated pneumonia, ventilator-associated events, and nonventilator hospital-acquired pneumonia in acute-care hospitals: 2022 Update Open
The purpose of this document is to highlight practical recommendations to assist acute care hospitals to prioritize and implement strategies to prevent ventilator-associated pneumonia (VAP), ventilator-associated events (VAE), and non-vent…
View article: Group B <i>Streptococcus</i> Infection in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years
Group B <i>Streptococcus</i> Infection in Extremely Preterm Neonates and Neurodevelopmental Outcomes at 2 Years Open
Background This study was performed to determine the incidence of group B Streptococcus (GBS) disease among extremely preterm infants and assess to risk of death or neurodevelopmental impairment (NDI) at a corrected age of 18–26 months. Me…
View article: Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions
Neurodevelopmental outcomes following neonatal late-onset sepsis and blood culture-negative conditions Open
Objective Determine risk of death or neurodevelopmental impairment (NDI) in infants with late-onset sepsis (LOS) versus late-onset, antibiotic-treated, blood culture-negative conditions (LOCNC). Design Retrospective cohort study. Setting 2…
View article: Cerebral Pulsed Arterial Spin Labeling Perfusion Weighted Imaging Predicts Language and Motor Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy
Cerebral Pulsed Arterial Spin Labeling Perfusion Weighted Imaging Predicts Language and Motor Outcomes in Neonatal Hypoxic-Ischemic Encephalopathy Open
Rationale and Objectives: To compare cerebral pulsed arterial spin labeling (PASL) perfusion among controls, hypoxic ischemic encephalopathy (HIE) neonates with normal conventional MRI(HIE/MRI⊕), and HIE neonates with abnormal conventional…
View article: Carbon dioxide clearance using bubble CPAP with superimposed high frequency oscillations in a premature infant lung model with abnormal lung mechanics
Carbon dioxide clearance using bubble CPAP with superimposed high frequency oscillations in a premature infant lung model with abnormal lung mechanics Open
Background: High frequency (HF) oscillatory ventilation has been shown to improve CO2 clearance in premature infants. In a previous in vitro lung model with normal lung mechanics we demonstrated significantly improved CO2 washout by HF osc…
View article: The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach
The Diagnosis of Bronchopulmonary Dysplasia in Very Preterm Infants. An Evidence-based Approach Open
Rationale: Current diagnostic criteria for bronchopulmonary dysplasia rely heavily on the level and duration of oxygen therapy, do not reflect contemporary neonatal care, and do not adequately predict childhood morbidity.Objectives: To det…
View article: Tidal Breathing Measurements at Discharge and Clinical Outcomes in Extremely Low Gestational Age Neonates
Tidal Breathing Measurements at Discharge and Clinical Outcomes in Extremely Low Gestational Age Neonates Open
Extremely premature infants receiving less than 1 L/min nasal cannula support at 21% to 100% fraction of inspired oxygen have tidal breathing measurements that differ from term infants, but these measurements do not differentiate those pre…