Explanipedia

Editorial: The acetaminophen scare: association vs causation Open

Éric Fombonne · 2025

With high twin concordance and sibling recurrence risk, the influence of genetic factors in the etiology of autism is not disputed. The contribution of environmental risk to the etiology of autism is less well established. While the preval…

Pathways to autism diagnosis in adulthood Open

Isabelle Dufour, Yohann Chiu, Sébastien Brodeur, Mireille Courteau, Josiane Courteau , et al. · 2025

Male and Female Healthcare Trajectories in Autism: Are There Any Differences Considering Age at Diagnosis and Intellectual or Developmental Disabilities Status? Open

Mélanie Couture, Josiane Courteau, Sébastien Brodeur, Yohann Chiu, Mireille Courteau , et al. · 2025

The aim of this study was to compare the healthcare trajectories (HCTs) 2 years after a first diagnosis of autism according to sex, age at diagnosis, and intellectual or developmental disabilities (IDD) status. This is a retrospective coho…

Editorial: An autism case series, vaccine hesitancy, and death by measles Open

Éric Fombonne · 2024

Prevalence of Autism Spectrum Disorders in Guanajuato, Mexico: The Leon survey Open

Éric Fombonne, Carlos Marcín, Ana Cecilia Manero, Ruth Bruno, Christian Diaz , et al. · 2024

Provider perspectives on equity in use of mobile health autism screening tools Open

Katharine E. Zuckerman, Luis Andres Rivas Vazquez, Yesenia Morales Santos, Plyce Fuchu, Sarabeth Broder‐Fingert , et al. · 2023

Mobile health (mHealth) screening tools for autism are gaining in prevalence, and have benefits such as video content and direct resources linkage. However, it is unclear whether such tools will ameliorate autism inequities or will help on…

Association between relative age at school and persistence of ADHD in prospective studies: an individual participant data meta-analysis Open

Corentin J. Gosling, Serge Caparos, Charlotte Pinabiaux, Guido Schwarzer, Gerta Rücker , et al. · 2023

Editorial: Is autism overdiagnosed? Open

Éric Fombonne · 2023

After attention was drawn in the late 1960s to the poor reproducibility of psychiatric diagnosis between clinicians, methods and procedures used to diagnose psychiatric disorders were greatly improved. Sources of variance contributing to t…

A framework for measuring the cost to families of caring for children’s health: the design, methodology, and study population of the r-Kids study Open

Joanna E. Bulkley, Alexandra Varga, John F. Dickerson, Phil Crawford, Lisa Croen , et al. · 2023

Consistency and reliability of automated language measures across expressive language samples in autism Open

Heather MacFarlane, Alexandra C. Salem, Steven Bedrick, Jill K. Dolata, Jack Wiedrick , et al. · 2023

Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder with substantial clinical heterogeneity, especially in language and communication ability. There is a need for validated language outcome measures that show sensitivity to tru…

A Statistical Approach for Quantifying Group Difference in Topic Distributions Using Clinical Discourse Samples Open

Grace O. Lawley, Peter A. Heeman, Jill K. Dolata, Éric Fombonne, Steven Bedrick · 2023

Topic distribution matrices created by topic models are typically used for document classification or as features in a separate machine learning algorithm. Existing methods for evaluating these topic distributions include metrics such as c…

Mobile and online consumer tools to screen for autism do not promote equity Open

Benjamin Sanders, Steven Bedrick, Sarabeth Broder‐Fingert, Shannon A Brown, Jill K. Dolata , et al. · 2022

Limited access to screening and evaluation for autism spectrum disorder in children is a major barrier to improving outcomes for marginalized families. To identify and evaluate available digital autism spectrum disorder screening resources…

Incidence, prevalence, and global burden of autism spectrum disorder from 1990 to 2019 across 204 countries Open

Marco Solmi, Minjin Song, Dong Keon Yon, Seung Won Lee, Éric Fombonne , et al. · 2022

Issue Information Open

Edmund Sonuga‐Barke, Éric Fombonne, Scott H. Kollins, Arne Lervåg, Joan L. Luby , et al. · 2022

MSWord or WordPerfect, and should be PC compatible.If using other pack ages the fi le

“Um” and “Uh” Usage Patterns in Children with Autism: Associations with Measures of Structural and Pragmatic Language Ability Open

Grace O. Lawley, Steven Bedrick, Heather MacFarlane, Jill K. Dolata, Alexandra C. Salem , et al. · 2022

Analysis of a Repetitive Language Coding System: Comparisons between Fragile X Syndrome, Autism, and Down Syndrome Open

Anne Hoffmann, Angela John Thurman, Audra Sterling, Sara T. Kover, Lizbeth H. Finestack , et al. · 2022

Expressive language sampling (ELS) is a frequently used tool for language analysis, as it can be used across widely ranging cognitive and language abilities. ELS can also evaluate pragmatic language, including excessive self-repetition, wh…

Combining voice and language features improves automated autism detection Open

Heather MacFarlane, Alexandra C. Salem, Liu Chen, Meysam Asgari, Éric Fombonne · 2022

Variability in expressive and receptive language, difficulty with pragmatic language, and prosodic difficulties are all features of autism spectrum disorder (ASD). Quantifying language and voice characteristics is an important step for mea…

Pragmatic language markers of autism diagnosis and severity Open

Jill K. Dolata, Shannon Suarez, Beth Calamé, Éric Fombonne · 2022

Global prevalence of autism: A systematic review update Open

Jinan Zeidan, Éric Fombonne, Julie Scorah, Alaa T. Ibrahim, Maureen S. Durkin , et al. · 2022

Prevalence estimates of autism are essential for informing public policy, raising awareness, and developing research priorities. Using a systematic review, we synthesized estimates of the prevalence of autism worldwide. We examined factors…

Emotional and Behavioral Problems in Youth with Autism: High Prevalence and Impact on Functioning Open

Éric Fombonne, Lisa Croen, Joanna E. Bulkley, Alexandra Varga, Yihe G. Daida , et al. · 2021

Objective: Emotional and behavioral problems (EBPs) may co-occur with autism spectrum disorder (ASD) and impair children's functioning beyond autism symptomatology. We compared the prevalence of EBPs in youths with or without ASD and evalu…

Parents' Concerns Are Associated with Early Intervention Evaluation and Eligibility Outcomes Open

Mohadeseh Solgi, Alicia Feryn, Alison E. Chavez, Laura C. Wilson, Margaret King , et al. · 2021

Objective: To test the association of parents' concerns with early intervention (EI) developmental services outcomes including evaluation, eligibility, and enrollment in services. Method: We collected survey data on parents' concerns and E…

Quantifying Voice Characteristics for Detecting Autism Open

Meysam Asgari, Liu Chen, Éric Fombonne · 2021

The presence of prosodic anomalies in autistic is recognized by experienced clinicians but their quantitative analysis is a cumbersome task beyond the scope of typical pen and pencil assessment. This paper proposes an automatic approach al…

A Pseudo-Value Approach to Analyze the Semantic Similarity of the Speech of Children With and Without Autism Spectrum Disorder Open

Joel Adams, Alexandra C. Salem, Heather MacFarlane, Rosemary Ingham, Steven Bedrick , et al. · 2021

Conversational impairments are well known among people with autism spectrum disorder (ASD), but their measurement requires time-consuming manual annotation of language samples. Natural language processing (NLP) has shown promise in identif…

Evaluating atypical language in autism using automated language measures Open

Alexandra C. Salem, Heather MacFarlane, Joel Adams, Grace O. Lawley, Jill K. Dolata , et al. · 2021

Parental Age and the Risk of Autism Spectrum Disorder in Oman Open

Watfa Al‐Mamari, Ahmed B. Idris, Aala' A Al-Zadjali, Saquib Jalees, Sathiya Murthi , et al. · 2021

Both maternal and paternal increased age were associated with a higher risk of ASD; however, the association was more pronounced and more consistent with advanced maternal age compared to paternal age.

Psychometric properties of the Chinese Parent Version of the Autism Spectrum Rating Scale: Rasch analysis Open

Weili Yan, Richard J. Siegert, Hao Zhou, Xiaobing Zou, Lijie Wu , et al. · 2021

The recent adaptation of a Chinese parent version of the Autism Spectrum Rating Scale showed the Modified Chinese Autism Spectrum Rating Scale to be reliable and valid for use in China. The aim of this study was to test the Modified Chines…

Cohort Profile: The TEMPO Cohort Study Open

Murielle Mary‐Krause, Joel José Herranz Bustamante, Camille Bolze, Cédric Galéra, Éric Fombonne , et al. · 2021

International audience

Autism questionnaire scores do not only rise because of autism Open

Éric Fombonne, Hadley Morotti, Sarah Mastel, Kory Keller, Rebecca Barnard , et al. · 2020

EDITOR—We wish to respond to Morris et al.'s letter regarding our study and methodology.1, 2 In our study, Social Responsiveness Scale (SRS) mean differences between neurofibromatosis type 1 (NF1) and controls became negligible when they w…

Improving autism and developmental screening and referral in US primary care practices serving Latinos Open

Katharine E. Zuckerman, Alison E. Chavez, Laura C. Wilson, Katie Unger, Colleen Reuland , et al. · 2020

Improving autism spectrum disorder screening and referral in primary care may reduce autism spectrum disorder disparities for Latino children. The REAL-START intervention aimed to increase primary care provider adherence to autism spectrum…

Prevalence and Interpretation of Recent Trends in Rates of Pervasive Developmental Disorders Open

Éric Fombonne, Sara Quirke, Arlene Hagen · 2020

The aims of this article are to provide an up-to-date review of the methodological features and substantive results of published epidemiological surveys of the prevalence of pervasive developmental disorders (PDD). This article updates pre…

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