Éric Sanchez
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View article: Towards a Model for Characterizing instruments Used in Design-Based Research
Towards a Model for Characterizing instruments Used in Design-Based Research Open
The aim of this paper is to characterize and discuss the features of instruments that might be useful to carry out design-based research (DBR). DBR is a method of conducting educational research in real educational settings. DBR aims to br…
View article: Digitizing Touch with an Artificial Multimodal Fingertip
Digitizing Touch with an Artificial Multimodal Fingertip Open
Touch is a crucial sensing modality that provides rich information about object properties and interactions with the physical environment. Humans and robots both benefit from using touch to perceive and interact with the surrounding enviro…
View article: Reorienting Learning Game Design in Design-Based Research: a Case Study
Reorienting Learning Game Design in Design-Based Research: a Case Study Open
One of the main difficulties remains the collaboration between the various experts involved in designing the Learning Games (LG). Our literature review focuses on the pitfalls and principles that have been identified by various authors in …
View article: Museum Games and Personal Epistemology: A Study on Students’ Critical Thinking with a Mixed Reality Game
Museum Games and Personal Epistemology: A Study on Students’ Critical Thinking with a Mixed Reality Game Open
This study examines how 12-15-year-old students use information while playing Geome, a mixed reality game intended for museum school visits. Geome presents environmental issues, prompting students and asking them to discern and dismiss mis…
View article: A Systematic Review: criteria and dimensions of learning experience
A Systematic Review: criteria and dimensions of learning experience Open
There has been an increased interest in evaluating students’ learning experiences in various academic domains. Some authors consider it an important aspect of education to assess the effectiveness of instructional methods, while others aim…
View article: Data from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Data from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
TNF receptor–associated factor 6 (TRAF6) has been implicated in polyubiquitin-mediated IL1R/TLR signaling through activation of IκB kinase (IKK) to regulate the NF-κB and JNK signaling pathways. Here, TRAF6 protein was determined to be ove…
View article: Supplemental Figure 1 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 1 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
Cloning of the pLenti6.2-hTRAF6dn vector. The TRAF6dn cDNA was cloned into PCRII TOPO vector to produce a 167-amino acid peptide and then sub-cloned into a pLenti6.2 expression vector (pLenti6.2-hTRAF6dn).
View article: Supplemental Figure 3 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 3 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
Evaluation of AKT signaling pathway in primary MM cells treated with a TRAF6dn inhibitory peptide.
View article: Supplemental Figure 3 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 3 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
Evaluation of AKT signaling pathway in primary MM cells treated with a TRAF6dn inhibitory peptide.
View article: Supplemental Figure 1 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 1 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
Cloning of the pLenti6.2-hTRAF6dn vector. The TRAF6dn cDNA was cloned into PCRII TOPO vector to produce a 167-amino acid peptide and then sub-cloned into a pLenti6.2 expression vector (pLenti6.2-hTRAF6dn).
View article: Data from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Data from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
TNF receptor–associated factor 6 (TRAF6) has been implicated in polyubiquitin-mediated IL1R/TLR signaling through activation of IκB kinase (IKK) to regulate the NF-κB and JNK signaling pathways. Here, TRAF6 protein was determined to be ove…
View article: Supplemental Figure 2 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 2 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
TRAF6dn FITC-labeled peptide cultured with MM cell lines for 72 hours and monitored FITC positive MM cells using immunofluorescent microscopy (20X).
View article: Supplemental Figure 2 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects
Supplemental Figure 2 from Combined TRAF6 Targeting and Proteasome Blockade Has Anti-myeloma and Anti-Bone Resorptive Effects Open
TRAF6dn FITC-labeled peptide cultured with MM cell lines for 72 hours and monitored FITC positive MM cells using immunofluorescent microscopy (20X).
View article: Getting Ahead: A Resident Led Quality Improvement Project to Increase Diabetic Nephropathy Screening in an Underserved Hispanic-Predominant Population
Getting Ahead: A Resident Led Quality Improvement Project to Increase Diabetic Nephropathy Screening in an Underserved Hispanic-Predominant Population Open
Our study showed promising results on improving diabetic nephropathy screening. The comprehensive approach including resident education about diabetic nephropathy screening with UACR and more so facilitating the order set in the EMR were k…
View article: Toward a Digital Companion to Monitor a Mixed Reality Game
Toward a Digital Companion to Monitor a Mixed Reality Game Open
The game orchestration by the game master during a game-based learning session requires to (1) collect data from player interactions, (2) visualize indicators built with this data, (3) take decisions regarding the monitoring of the activit…
View article: <sup>18</sup>F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models
<sup>18</sup>F-FDG PET Visualizes Systemic STING Agonist-Induced Lymphocyte Activation in Preclinical Models Open
Stimulator of interferon genes (STING) is a mediator of immune recognition of cytosolic DNA, which plays important roles in cancer, cytotoxic therapies, and infections with certain pathogens. Although pharmacologic STING activation stimula…
View article: What do you mean by learning lab?
What do you mean by learning lab? Open
Digital and innovation competencies are nowadays highly required for students and faculty members in higher education institutions. We therefore need environments that incubate innovative learning scenarios to develop these competencies. W…
View article: The co.LAB Generic Framework for Collaborative Design of Serious Games: Development Study
The co.LAB Generic Framework for Collaborative Design of Serious Games: Development Study Open
Background Serious games are increasingly used at all levels of education. However, research shows that serious games do not always fulfill all the targeted pedagogical objectives. Designing efficient and engaging serious games is a diffic…
View article: The co.LAB Generic Framework for Collaborative Design of Serious Games: Development Study (Preprint)
The co.LAB Generic Framework for Collaborative Design of Serious Games: Development Study (Preprint) Open
BACKGROUND Serious games are increasingly used at all levels of education. However, research shows that serious games do not always fulfill all the targeted pedagogical objectives. Designing efficient and engaging serious games is a diffi…
View article: From Design to Management of Digital Epistemic Games
From Design to Management of Digital Epistemic Games Open
The development of pedagogies that can provide alternatives to traditional approaches is becoming increasingly important as a means of enhancing the attractiveness of training courses, appealing to new types of learners and designing learn…