Eric M. Dowling
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View article: Transoral excision of a parapharyngeal thyroglossal duct cyst and parapharyngeal second branchial cleft cyst: A report of two rare cases in adult patients with a comprehensive literature review
Transoral excision of a parapharyngeal thyroglossal duct cyst and parapharyngeal second branchial cleft cyst: A report of two rare cases in adult patients with a comprehensive literature review Open
Thyroglossal duct cysts (TDCs) and branchial cleft cysts (BCCs) are common congenital neck anomalies that typically present in children. However, their occurrence in the parapharyngeal space is exceedingly rare. Standard management usually…
View article: Otolaryngology practitioner attitudes toward human papillomavirus vaccination in academic otolaryngology clinics
Otolaryngology practitioner attitudes toward human papillomavirus vaccination in academic otolaryngology clinics Open
Despite the existence of a highly effective and safe vaccine against human papillomavirus (HPV) infection, vaccination rates remain low. The most prevalent HPV-associated malignancy in the United States is oropharyngeal cancer, but otolary…
View article: Impact of implementing stricter criteria for blood transfusion in patients with head and neck cancer undergoing free tissue transfer
Impact of implementing stricter criteria for blood transfusion in patients with head and neck cancer undergoing free tissue transfer Open
Objective Recent literature studying the impact of blood transfusion on outcomes in patients with head and neck cancer (HNC) have shown that blood transfusions are associated with increased risk of death and higher wound infection rates. T…
View article: Human Papilloma Virus Positive Oropharyngeal Squamous Cell Carcinoma and the Immune System: Pathogenesis, Immunotherapy and Future Perspectives
Human Papilloma Virus Positive Oropharyngeal Squamous Cell Carcinoma and the Immune System: Pathogenesis, Immunotherapy and Future Perspectives Open
Oropharyngeal squamous cell carcinoma (OPSCC), a subset of head and neck squamous cell carcinoma (HNSCC), involves the palatine tonsils, soft palate, base of tongue, and uvula, with the ability to spread to adjacent subsites. Personalized …
View article: Oncocytic carcinoma of the thyroid: Conclusions from a 20‐year patient cohort
Oncocytic carcinoma of the thyroid: Conclusions from a 20‐year patient cohort Open
Background Oncocytic carcinoma (OCA) was recently reclassified as a distinct differentiated thyroid carcinoma (DTC). Given its rarity, OCA studies are limited. This study describes the characteristics of OCA in a 20‐year cohort. Methods Re…
View article: Synchronous thyroid cancer and malignant struma ovarii: concordant mutations and microRNA profile, discordant loss of heterozygosity loci
Synchronous thyroid cancer and malignant struma ovarii: concordant mutations and microRNA profile, discordant loss of heterozygosity loci Open
Background Struma ovarii is an unusual ovarian teratoma containing predominantly thyroid tissue. Less than 10% of cases undergo malignant transformation in the thyroid tissue and are considered malignant struma ovarii (MSO). MSO have been …
View article: Contextualizing the Modern Epidemiology of Neurofibromatosis Type 2 in an Era of Heightened Detection of Sporadic Vestibular Schwannoma
Contextualizing the Modern Epidemiology of Neurofibromatosis Type 2 in an Era of Heightened Detection of Sporadic Vestibular Schwannoma Open
Objective: Closely paralleling previous radiologic studies, recent population-based prevalence data suggest sporadic vestibular schwannoma (VS) affects over one in 2,000 adults and up to one in 500 in those aged 70 years or older. Attribut…
View article: Identification of aggressive Gardner syndrome phenotype associated with a de novo <i>APC</i> variant, c.4666dup
Identification of aggressive Gardner syndrome phenotype associated with a de novo <i>APC</i> variant, c.4666dup Open
Gardner syndrome describes a variant phenotype of familial adenomatous polyposis (FAP), primarily characterized by extracolonic lesions including osteomas, dental abnormalities, epidermal cysts, and soft tissue tumors. We describe a 2-yr-o…
View article: Cochlear Implantation: An Overview
Cochlear Implantation: An Overview Open
A cochlear implant (CI) is a surgically implanted device for the treatment of severe to profound sensorineural hearing loss in children and adults. It works by transducing acoustic energy into an electrical signal, which is used to stimula…