Eric M. Moult
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View article: Mapping uterine calcium dynamics during the ovulatory cycle in live mice
Mapping uterine calcium dynamics during the ovulatory cycle in live mice Open
Uterine contraction patterns vary during the ovulatory cycle and throughout pregnancy, but prior measurements have produced limited and conflicting information on these patterns. We combined a virally delivered genetically encoded calcium …
View article: Mapping uterine calcium dynamics during the ovulatory cycle in live mice
Mapping uterine calcium dynamics during the ovulatory cycle in live mice Open
Uterine contraction patterns vary during the ovulatory cycle and throughout pregnancy but prior measurements have produced limited and conflicting information on these patterns. We combined a virally delivered genetically encoded calcium r…
View article: Assessment of Choriocapillaris Flow Prior to Nascent Geographic Atrophy Development Using Optical Coherence Tomography Angiography
Assessment of Choriocapillaris Flow Prior to Nascent Geographic Atrophy Development Using Optical Coherence Tomography Angiography Open
This study showed that significant impairments in CC blood flow could be detected locally prior to the development of nGA. These findings add to our understanding of the pathophysiologic changes that occur with atrophy development in AMD.
View article: Mapping memories: pulse-chase labeling reveals AMPA receptor dynamics during memory formation
Mapping memories: pulse-chase labeling reveals AMPA receptor dynamics during memory formation Open
A tool to map changes in synaptic strength during a defined time window could provide powerful insights into the mechanisms governing learning and memory. We developed a technique, Extracellular Protein Surface Labeling in Neurons (EPSILON…
View article: Retinal blood flow speed quantification at the capillary level using temporal autocorrelation fitting OCTA [Invited]
Retinal blood flow speed quantification at the capillary level using temporal autocorrelation fitting OCTA [Invited] Open
Optical coherence tomography angiography (OCTA) can visualize vasculature structures, but provides limited information about blood flow speed. Here, we present a second generation variable interscan time analysis (VISTA) OCTA, which evalua…
View article: Retinal blood flow speed quantification at the capillary level using temporal autocorrelation fitting OCTA
Retinal blood flow speed quantification at the capillary level using temporal autocorrelation fitting OCTA Open
Optical coherence tomography angiography (OCTA) can visualize vasculature structures, but provides limited information about the blood flow speeds. Here, we present a second generation variable interscan time analysis (VISTA) OCTA, which e…
View article: Ultrahigh Resolution OCT Markers of Normal Aging and Early Age-related Macular Degeneration
Ultrahigh Resolution OCT Markers of Normal Aging and Early Age-related Macular Degeneration Open
Proprietary or commercial disclosure may be found after the references.
View article: Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization
Local Geographic Atrophy Growth Rates Not Influenced by Close Proximity to Non-Exudative Type 1 Macular Neovascularization Open
SS-OCTA imaging combined with GA growth modeling and spatial statistical analysis enabled quantitative assessment of correlations between local GA growth rates and local distances-to-MNV. Our results are not consistent with non-exudative t…
View article: OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age Related Macular Degeneration
OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age Related Macular Degeneration Open
Neovascular age-related macular degeneration (AMD) can lead to rapid, irreversible vision loss in untreated eyes. While the pathogenesis of neovascular AMD remains incompletely understood, the choriocapillaris has been hypothesized as the …
View article: MULTISCALE CORRELATION OF MICROVASCULAR CHANGES ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY WITH RETINAL SENSITIVITY IN DIABETIC RETINOPATHY
MULTISCALE CORRELATION OF MICROVASCULAR CHANGES ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY WITH RETINAL SENSITIVITY IN DIABETIC RETINOPATHY Open
Purpose: To assess global, zonal, and local correlations between vessel density changes measured by optical coherence tomography angiography and retinal sensitivity measured by microperimetry across diabetic retinopathy severity. Methods: …
View article: Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits
Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits Open
The purpose of this study is to quantitatively assess correlations between local geographic atrophy (GA) growth rates and local optical coherence tomography angiography (OCTA)-measured choriocapillaris (CC) flow deficits. Thirty-eight eyes…
View article: Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics
Growth Modeling for Quantitative, Spatially Resolved Geographic Atrophy Lesion Kinetics Open
Our proposed growth modeling framework may enable more accurate measurements of spatial variations in GA growth rates.
View article: OCT-OCTA segmentation: combining structural and blood flow information to segment Bruch’s membrane
OCT-OCTA segmentation: combining structural and blood flow information to segment Bruch’s membrane Open
In this paper we present a fully automated graph-based segmentation algorithm that jointly uses optical coherence tomography (OCT) and OCT angiography (OCTA) data to segment Bruch’s membrane (BM). This is especially valuable in cases where…
View article: Developing a potential retinal OCT biomarker for local growth of geographic atrophy
Developing a potential retinal OCT biomarker for local growth of geographic atrophy Open
Geographic atrophy (GA), the advanced stage of age-related macular degeneration, is a leading cause of blindness. GA lesions are characterized by anisotropic growth and the ability to predict growth patterns would be valuable in assessing …