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View article: Transcriptomic biomarkers related to cardiac disease in childhood cancer survivors: a case-control study
Transcriptomic biomarkers related to cardiac disease in childhood cancer survivors: a case-control study Open
Background and Aims Cardiotoxic treatments like anthracyclines and heart-directed radiotherapy increase the risk of cardiac diseases (CDs) in childhood cancer survivors (CCSs), but individual differences in CD incidence are not fully under…
View article: Influence of genetic biomarkers on cardiac diseases in childhood cancer survivors: a systematic review
Influence of genetic biomarkers on cardiac diseases in childhood cancer survivors: a systematic review Open
View article: P-470. CD4 Testing in HIV Care: Uncovering Patterns of Over-Monitoring
P-470. CD4 Testing in HIV Care: Uncovering Patterns of Over-Monitoring Open
Background In the realm of HIV care, CD4 monitoring guidelines serve as a cornerstone for managing the health and treatment plans of individuals living with HIV. Various authoritative bodies, including the U.S. Department of Health and Hum…
View article: EPAC1 inhibition protects the heart from doxorubicin-induced toxicity
EPAC1 inhibition protects the heart from doxorubicin-induced toxicity Open
Anthracyclines, such as doxorubicin (Dox), are widely used chemotherapeutic agents for the treatment of solid tumors and hematologic malignancies. However, they frequently induce cardiotoxicity leading to dilated cardiomyopathy and heart f…
View article: Troubles de la marche d'origine neurologique : Utilité de l'analyse clinique de la marche illustrée dans le cas de l'hydrocéphalie à pression normale
Troubles de la marche d'origine neurologique : Utilité de l'analyse clinique de la marche illustrée dans le cas de l'hydrocéphalie à pression normale Open
L'analyse clinique de la marche permet aux cliniciens d'évaluer leurs patients, formuler une hypothèse diagnostique et assurer un suivi thérapeutique. Les troubles neurologiques de la marche incluent une palette large et variée de phénotyp…
View article: Progression of excitation-contraction coupling defects in doxorubicin cardiotoxicity
Progression of excitation-contraction coupling defects in doxorubicin cardiotoxicity Open
View article: Specific Activation of the Alternative Cardiac Promoter of <i>Cacna1c</i> by the Mineralocorticoid Receptor
Specific Activation of the Alternative Cardiac Promoter of <i>Cacna1c</i> by the Mineralocorticoid Receptor Open
Rationale: The MR (mineralocorticoid receptor) antagonists belong to the current therapeutic armamentarium for the management of cardiovascular diseases, but the mechanisms conferring their beneficial effects are poorly understood. Part of…
View article: Switchable Cardiac L Type Ca2+ Channel Transcript by Mineralocorticoid Pathway
Switchable Cardiac L Type Ca2+ Channel Transcript by Mineralocorticoid Pathway Open