Eric P. Borrelli
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View article: Enhancing Patient Safety and Charge Capture Through Smart Infusion Pump Interoperability: A Health Economic Analysis for US Health Systems
Enhancing Patient Safety and Charge Capture Through Smart Infusion Pump Interoperability: A Health Economic Analysis for US Health Systems Open
The implementation of smart infusion pump interoperability has the potential to enhance patient safety by reducing pADEs and improving outpatient administration charge capture. However, it is important to note that while the model is based…
View article: Evaluating the efficacy of blister packaging in improving medication adherence within psychiatry: A systematic literature review
Evaluating the efficacy of blister packaging in improving medication adherence within psychiatry: A systematic literature review Open
Introduction Medication nonadherence is a prevalent and significant public health issue in the United States, particularly among patients with psychiatric disorders. Blister packaging medications is one of the most widely recognized and va…
View article: The influence of medication adherence on Medicare Star Ratings: A decade-long analysis of health plan performance
The influence of medication adherence on Medicare Star Ratings: A decade-long analysis of health plan performance Open
Assessing a decade of the Medicare Star Rating performance data showed that MA health plans that performed well on the medication adherence measures also had a high rate of achieving a 4-star overall rating. Future research should explore …
View article: Evaluating the Impact of Smart Infusion Pump Interoperability on Reducing Medication Administration Errors: A Systematic Literature Review
Evaluating the Impact of Smart Infusion Pump Interoperability on Reducing Medication Administration Errors: A Systematic Literature Review Open
Smart infusion pump interoperability demonstrated consistent potential to enhance medication safety by addressing key error types and reducing cumulative errors in real-world settings. However, future research is needed to assess its impac…
View article: Enhancing medication adherence with blister-packed oral oncolytics: A case example in chronic lymphocytic leukemia
Enhancing medication adherence with blister-packed oral oncolytics: A case example in chronic lymphocytic leukemia Open
Introduction Medication nonadherence is a prevalent issue in the oncology population and can be costly on the healthcare system while leading to worsened outcomes, including increased mortality. One intervention that has been shown to help…
View article: Insights from a National Survey on Controlled Substance Diversion Practices in U.S. Hospital Pharmacies: Opportunities for Enhanced Surveillance and Compliance
Insights from a National Survey on Controlled Substance Diversion Practices in U.S. Hospital Pharmacies: Opportunities for Enhanced Surveillance and Compliance Open
This study explored controlled substance (CS) diversion surveillance practices within hospital pharmacies across the United States. A survey with questions based on published CS diversion risk points was conducted in May 2024. A total of 6…
View article: Enhancing Outcomes in Opioid Use Disorder Treatment: An Economic Evaluation of Improving Medication Adherence for Buprenorphine Through Blister-Packaging
Enhancing Outcomes in Opioid Use Disorder Treatment: An Economic Evaluation of Improving Medication Adherence for Buprenorphine Through Blister-Packaging Open
Blister-packaging buprenorphine for treatment of OUD has potential to improve medication adherence and health outcomes while reducing HCRU and health care costs. Future studies are necessary to assess the real-world application and impact …
View article: Improving Adherence and Reducing Health Care Costs Through Blister-Packaging: An Economic Model for a Commercially Insured Health Plan
Improving Adherence and Reducing Health Care Costs Through Blister-Packaging: An Economic Model for a Commercially Insured Health Plan Open
Blister-packaging chronic medications in a commercially insured population has the potential to reduce healthcare costs. Future research is needed to confirm these findings in real-world settings and to fully understand the clinical and ec…
View article: Estimating the economic impact of blister-packaging on medication adherence and health care costs for a Medicare Advantage health plan
Estimating the economic impact of blister-packaging on medication adherence and health care costs for a Medicare Advantage health plan Open
Dispensing chronic medications with blister-packaging for Medicare Advantage health plan patients was modeled to reduce HCRU and health care costs. Future studies are needed to assess whether the impact of blister-packaging medications is …
View article: The effect of antiretroviral therapy with high central nervous system penetration on HIV-related cognitive impairment: a systematic review and meta-analysis
The effect of antiretroviral therapy with high central nervous system penetration on HIV-related cognitive impairment: a systematic review and meta-analysis Open
Chronic complications are a significant concern for people living with HIV/AIDS (PLWHA) infection. HIV-associated neurocognitive disorders (HAND) are prevalent in PLWHA. Yet, the efficacy of medications that penetrate the central nervous s…
View article: Application of a diazepam milligram equivalency algorithm to assess benzodiazepine dose intensity in Rhode Island in 2018
Application of a diazepam milligram equivalency algorithm to assess benzodiazepine dose intensity in Rhode Island in 2018 Open
BACKGROUND: Benzodiazepines are indicated for the treatment of many conditions, such as anxiety disorders, muscle spasms, alcohol withdrawal, agitation, movement disorders, and epilepsy, and are one of the most frequently prescribed medica…
View article: The effectiveness and value of novel acute treatments for migraine
The effectiveness and value of novel acute treatments for migraine Open
DISCLOSURES: Funding for this summary was contributed by Arnold Ventures, California Health Care Foundation, Harvard Pilgrim Health Care, and Kaiser Foundation Health Plan to the Institute for Clinical and Economic Review (ICER), an indepe…
View article: Poster Abstracts - Academy of Managed Care Pharmacy Nexus 2020
Poster Abstracts - Academy of Managed Care Pharmacy Nexus 2020 Open
The AMCP NEXUS 2020 VIRTUAL will be held online the week of October 19, 2020. The AMCP abstracts program provides a forum through which authors can share their insights and outcomes of advanced managed care practice. For NEXUS 2020 VIRTUAL…
View article: Clozapine and hematologic adverse reactions: Impact of the Risk Evaluation and Mitigation Strategy program
Clozapine and hematologic adverse reactions: Impact of the Risk Evaluation and Mitigation Strategy program Open
Introduction In October 2015, the Food and Drug Administration (FDA) instituted an update to the mandatory Risk Evaluation and Mitigation Strategy (REMS) program for clozapine to improve safety monitoring of hematologic events. However, th…
View article: Meeting Abstracts - AMCP 2020
Meeting Abstracts - AMCP 2020 Open
The abstracts presented in this program were originally slated to be presented at the AMCP 2020 meeting in Houston, Texas, April 21-24. The meeting was canceled because of the COVID-19 crisis. In lieu of the scheduled poster presentations,…
View article: The art and science of drug titration
The art and science of drug titration Open
A “one-size-fits-all” approach has been the standard for drug dosing, in particular for agents with a wide therapeutic index. The scientific principles of drug titration, most commonly used for medications with a narrow therapeutic index, …
View article: PRESCRIPTION CONTROLLED SUBSTANCE UTILIZATION: EVALUATING BENZODIAZEPINE DOSE INTENSITY, DEVELOPMENT AND APPLICATION OF A MEASUREMENT FRAMEWORK, AND USE OF TRAMADOL AMONG PATIENTS WITH HIGHER RISK
PRESCRIPTION CONTROLLED SUBSTANCE UTILIZATION: EVALUATING BENZODIAZEPINE DOSE INTENSITY, DEVELOPMENT AND APPLICATION OF A MEASUREMENT FRAMEWORK, AND USE OF TRAMADOL AMONG PATIENTS WITH HIGHER RISK Open
Approximately 50 million adults in the United States (U.S.) suffered from chronic pain in 2016, with almost 20 million of whom had high impact pain that interfered with work or daily life. In 2017, there were more than 75 million dispensed…
View article: Meeting Abstracts - Academy of Managed Care Pharmacy Nexus 2019
Meeting Abstracts - Academy of Managed Care Pharmacy Nexus 2019 Open
AMCP Nexus 2019: The Intersection of Value and Care, in National Harbor, MD, is expected to attract more than 2,400 managed care pharmacists and other health care professionals who manage and evaluate drug therapies, develop and manage net…
View article: Costs of medical care for mesothelioma
Costs of medical care for mesothelioma Open
Malignant mesothelioma is a rare and devastating form of cancer with an increasing economic burden. We sought to describe the direct cost burden of mesothelioma to the US health system. A systematic literature review was performed to locat…
View article: Stevens‐Johnson syndrome and toxic epidermal necrolysis with antiepileptic drugs: An analysis of the US Food and Drug Administration Adverse Event Reporting System
Stevens‐Johnson syndrome and toxic epidermal necrolysis with antiepileptic drugs: An analysis of the US Food and Drug Administration Adverse Event Reporting System Open
Summary Objective Stevens‐Johnson syndrome ( SJS ) and toxic epidermal necrolysis ( TEN ) are rare and potentially fatal adverse skin reactions that are most commonly triggered by certain medications. One class of medications that has been…
View article: Trends in Hospitalizations for Celiac Disease in the United States
Trends in Hospitalizations for Celiac Disease in the United States Open
Celiac disease is a severe autoimmune disease that results in patients having an intolerance to gluten. Patients that have celiac disease and ingest gluten can have gastrointestinal related adverse effects. There is currently no cure or tr…
View article: Inpatient Hospital Costs for Celiac Disease in the United States in 2014
Inpatient Hospital Costs for Celiac Disease in the United States in 2014 Open
Celiac disease (CD) is a rare autoimmune disease that affects approximately 0.5 to1% of the United States (U.S.) population. Patients with CD have gastrointestinal disturbances resulting from eating gluten. The only treatment therapy avail…
View article: 2870Glycemic variability assessed by continuous glucose monitoring and antiplatelet responsiveness in patients undergoing coronary stenting: results from the observational GLYVAR study
2870Glycemic variability assessed by continuous glucose monitoring and antiplatelet responsiveness in patients undergoing coronary stenting: results from the observational GLYVAR study Open
cluded: a) Light transmission aggregometry (LTA), using 20 (primary endpoint) and 5 mM ADP as agonists; b) VASP analysis; c) Multiple electrode aggregometry (Multiplate), using ADP as agonist; and d) the Verifynow P2Y12 Assay.Only subjects…
View article: Clinico-pathological profile evaluation in patients affected by chronic inflammatory bowel diseases
Clinico-pathological profile evaluation in patients affected by chronic inflammatory bowel diseases Open
Introduction Inflammatory bowel diseases (IBDs) have high social impact. Aetiology is still unknown, however multifactorial genesis is surely implicated. We tried to correlate IBDs and psychological distress through evaluated psychometrica…
View article: Maybe it is More than Pneumonia: Case Report of an Intralobar Sequestration in a 20-Year-Old Male
Maybe it is More than Pneumonia: Case Report of an Intralobar Sequestration in a 20-Year-Old Male Open
Pulmonary sequestration (PS) is rare congenital lung malformation typically diagnosed with fetal ultrasound or computed tomography scans.Potential complications of PS include recurrent respiratory infections, hemorrhage, heart failure, and…