Eric M. Yoshida
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View article: Ethnic disparities in extrahepatic manifestations among people with HCV infection: a population-based study in British Columbia
Ethnic disparities in extrahepatic manifestations among people with HCV infection: a population-based study in British Columbia Open
Background Ethnic disparities in extrahepatic manifestations (EHMs) among individuals with chronic hepatitis C virus (HCV) infection are poorly understood, especially in diverse populations. We aimed to examine ethnic disparities in EHMs a…
View article: Assessment of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Cross-sectional Study in Asymptomatic Individuals in Greater Vancouver
Assessment of Metabolic Dysfunction-associated Steatotic Liver Disease and Liver Fibrosis: A Cross-sectional Study in Asymptomatic Individuals in Greater Vancouver Open
A substantial proportion of asymptomatic individuals in Greater Vancouver have undetected MASLD and significant fibrosis. Early identification of high-risk groups may support broader implementation of transient elastography screening. This…
View article: Post-Liver Transplantation Hepatitis B Prophylaxis in Canada: Results of a National Survey
Post-Liver Transplantation Hepatitis B Prophylaxis in Canada: Results of a National Survey Open
While HBIG and NA combination therapy remains the standard in Canada, significant variations exist in HBIG duration and recurrence management. A growing shift toward HBIG-free regimens in select populations highlights the need for standard…
View article: Incidence of luminal gastrointestinal cancers in patients with cirrhosis: A systematic review and meta-analysis
Incidence of luminal gastrointestinal cancers in patients with cirrhosis: A systematic review and meta-analysis Open
BACKGROUND The global incidence of cirrhosis and luminal gastrointestinal cancers are increasing. It is unknown if cirrhosis itself is a predisposing factor for luminal gastrointestinal cancer. Such an association would have significant cl…
View article: Cross-sectional study of resident physician knowledge and perceptions regarding MASLD in Canada
Cross-sectional study of resident physician knowledge and perceptions regarding MASLD in Canada Open
Background: Metabolic dysfunction-associated steatotic liver disease (MASLD) affects approximately 25% of Canadians. As its prevalence grows, it is crucial for future primary care physicians to have a thorough understanding of MASLD to imp…
View article: Methods and validation of velacur determined fat fraction in patients with MASLD
Methods and validation of velacur determined fat fraction in patients with MASLD Open
The Velacur Determined Fat Fraction (VDFF) is an accurate and accessible way to estimate steatosis as measured by MRI-PDFF. Velacur VDFF can fill the unmet need of an accurate means to diagnosis hepatic steatosis and serve as a potential a…
View article: Association of hepatitis B virus treatment with all-cause and liver-related mortality among individuals with HBV and cirrhosis: a population-based cohort study
Association of hepatitis B virus treatment with all-cause and liver-related mortality among individuals with HBV and cirrhosis: a population-based cohort study Open
Summary: Background: We evaluated the association of hepatitis B virus (HBV) treatment with all-cause, and liver-related mortality among individuals with HBV and cirrhosis in British Columbia (BC), Canada. Methods: This analysis included p…
View article: Impact of <scp>COVID</scp>‐19 pandemic on hepatocellular carcinoma surveillance in British Columbia, Canada: An interrupted time series study
Impact of <span>COVID</span>‐19 pandemic on hepatocellular carcinoma surveillance in British Columbia, Canada: An interrupted time series study Open
We assessed the impact of the COVID‐19 pandemic on hepatocellular carcinoma (HCC) surveillance among individuals with HCV diagnosed with cirrhosis in British Columbia (BC), Canada. We used data from the British Columbia Hepatitis Testers C…
View article: “My feelings and my thoughts are my lived experience, not the numbers they show me on a piece of paper”: Indigenous experiences of liver transplantation in British Columbia, Canada
“My feelings and my thoughts are my lived experience, not the numbers they show me on a piece of paper”: Indigenous experiences of liver transplantation in British Columbia, Canada Open
Indigenous Peoples in Canada face healthcare inequities impacting access to solid organ transplantation. The experiences of Indigenous patients during the liver transplant process, and how transplant professionals perceive challenges faced…
View article: Incidence of Luminal Gastrointestinal Cancers in Patients with Cirrhosis: A Systematic Review and Meta-analysis
Incidence of Luminal Gastrointestinal Cancers in Patients with Cirrhosis: A Systematic Review and Meta-analysis Open
Background: The global incidence of cirrhosis and luminal gastrointestinal cancers are increasing. It is unknown if cirrhosis itself is a predisposing factor for luminal gastrointestinal cancer. Aims: The aim of our study was to investigat…
View article: Velacur ACE outperforms FibroScan CAP for diagnosis of MASLD
Velacur ACE outperforms FibroScan CAP for diagnosis of MASLD Open
Background: As the prevalence of metabolic dysfunction-associated steatotic liver disease increases, it is imperative to have noninvasive alternatives to liver biopsy. Velacur offers a non-invasive, point-of-care ultrasound-based method fo…
View article: A306 A CASE OF SCLEROSING CHOLANGITIS AS A COMPLICATION OF CAR-T THERAPY
A306 A CASE OF SCLEROSING CHOLANGITIS AS A COMPLICATION OF CAR-T THERAPY Open
Background Chimeric antigen receptor T-cell (CAR-T) therapy is a novel immunotherapy for treating hematological malignancies. CAR-T therapy starts with the collection of T-cells from patients. Then, receptors on the T-cell membrane are re-…
View article: A279 WHY LIVER TRANSPLANT RECIPIENTS DIE: A QUALITY ASSURANCE REVIEW
A279 WHY LIVER TRANSPLANT RECIPIENTS DIE: A QUALITY ASSURANCE REVIEW Open
Background Liver transplant techniques have significantly advanced over time, enhancing patient survival rates. In 2022, 99 liver transplants were performed in British Columbia (BC), ranking second in organ transplants. In BC, mortality ra…
View article: A121 CROSS-SECTIONAL STUDY OF RESIDENT PHYSICIAN KNOWLEDGE AND PERCEPTIONS REGARDING NON-ALCOHOLIC FATTY LIVER DISEASE IN CANADA
A121 CROSS-SECTIONAL STUDY OF RESIDENT PHYSICIAN KNOWLEDGE AND PERCEPTIONS REGARDING NON-ALCOHOLIC FATTY LIVER DISEASE IN CANADA Open
Background Non-alcoholic Fatty Liver Disease (NAFLD) is a prevalent condition affecting approximately 25% of the Canadian population and is projected to continue increasing. Given the increasing prevalence and complications of NAFLD, it is…
View article: A285 COMPARISON OF ADVERSE OUTCOMES IN PATIENTS WITH COMBINED INFLAMMATORY BOWEL DISEASE AND PRIMARY SCLEROSING CHOLANGITIS VERSUS ISOLATED PRIMARY SCLEROSING CHOLANGITIS
A285 COMPARISON OF ADVERSE OUTCOMES IN PATIENTS WITH COMBINED INFLAMMATORY BOWEL DISEASE AND PRIMARY SCLEROSING CHOLANGITIS VERSUS ISOLATED PRIMARY SCLEROSING CHOLANGITIS Open
Background Primary sclerosing cholangitis (PSC) results in progressive inflammation and fibrosis of bile ducts causing chronic cholestasis. PSC is associated with an increased risk of malignancy [hepatobiliary and colorectal cancers (CRC)]…
View article: Comprehensive immune profiling of SARS-CoV-2 infected kidney transplant patients
Comprehensive immune profiling of SARS-CoV-2 infected kidney transplant patients Open
Introduction The immune responses of kidney transplant recipients against SARS-CoV-2 remains under studied. Methods In this prospective pilot study, we performed comprehensive immune profiling using cellular, proteomic, and serologic assay…
View article: Prolonged and Recurrent Intrahepatic Cholestasis of Pregnancy
Prolonged and Recurrent Intrahepatic Cholestasis of Pregnancy Open
Intrahepatic cholestasis of pregnancy is one of the most common disorders of pregnancy, which typically resolves in the postpartum period. Intrahepatic cholestasis is characterized by elevated bile acid levels that present as pruritus. The…
View article: Efficacy and safety of semaglutide in non-alcoholic fatty liver disease
Efficacy and safety of semaglutide in non-alcoholic fatty liver disease Open
Acute pancreatitis (AP) is a potentially life-threatening inflammatory disease of the pancreas, with clinical management determined by the severity of the disease. Diagnosis, severity prediction, and prognosis assessment of AP typically in…
View article: Albuminuria post–liver transplant is a predictor of kidney disease progression and mortality
Albuminuria post–liver transplant is a predictor of kidney disease progression and mortality Open
BACKGROUND: Albuminuria is a marker of chronic kidney disease (CKD) associated with an increased risk of end-stage kidney disease (ESKD) and mortality in the general population, but it is uncertain whether the same association exists in li…