Erick Perera
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View article: Decitabine-induced DNA methylation remodeling reveals targetable biological processes in gilthead seabream pituitary and liver explants
Decitabine-induced DNA methylation remodeling reveals targetable biological processes in gilthead seabream pituitary and liver explants Open
Epigenetic manipulations have the potential to improve traits in farmed fish. To explore this opportunity in the gilthead seabream (Sparus aurata), the catalytic domains of five DNA methyltransferases (DNMTs) were predicted by homology mod…
View article: The Ghrelin Analog GHRP-6, Delivered Through Aquafeeds, Modulates the Endocrine and Immune Responses of Sparus aurata Following IFA Treatment
The Ghrelin Analog GHRP-6, Delivered Through Aquafeeds, Modulates the Endocrine and Immune Responses of Sparus aurata Following IFA Treatment Open
The aquaculture industry has experienced considerable growth in recent decades, stimulating research into sustainable and functional feed formulations, mainly related to using high-quality, safe, and environmentally friendly feed ingredien…
View article: One‑carbon nutrients and genistein as nutritional programming effectors in juvenile gilthead seabream (Sparus aurata): Contrasting effects on phenotypic traits
One‑carbon nutrients and genistein as nutritional programming effectors in juvenile gilthead seabream (Sparus aurata): Contrasting effects on phenotypic traits Open
Several studies have been conducted on the nutritional programming of farmed fish. Genistein (GEN) and one‑carbon nutrients (1C) produce different epigenetic effects, being suitable candidates as nutritional programming effectors. We fed j…
View article: Digestive and metabolic consequences of on-growing greater amberjack (Seriola dumerili) juveniles at different temperatures. In-vivo and ex-vivo assessment
Digestive and metabolic consequences of on-growing greater amberjack (Seriola dumerili) juveniles at different temperatures. In-vivo and ex-vivo assessment Open
Aiming to elucidate the effects of temperature on different aspects of the fish digestive physiology that may affect the growth, we examined, firstly, variations in growth performance, feed intake, digestive enzyme activities, expression o…
View article: High plant protein diet impairs growth performance and intestinal integrity in greater amberjack (Seriola dumerili): Molecular and physiological insights
High plant protein diet impairs growth performance and intestinal integrity in greater amberjack (Seriola dumerili): Molecular and physiological insights Open
The Mediterranean aquaculture industry that produces mainly seabream and seabass is exploring alternative plant-based protein sources for fish feeds together with the diversification of fish species. Effective plant-based formulations requ…
View article: The role of feeding as synchronizer of gut microbiota dynamics and its potential contribution to protein digestion in greater amberjack (Seriola dumerili)
The role of feeding as synchronizer of gut microbiota dynamics and its potential contribution to protein digestion in greater amberjack (Seriola dumerili) Open
Gut microbial communities are highly dynamic and respond to factors such as diet and host metabolism. However, there is limited information about how these responses can generate community dynamics at different time scales, such as circadi…
View article: Tissue explants as tools for studying the epigenetic modulation of the GH-IGF-I axis in farmed fish
Tissue explants as tools for studying the epigenetic modulation of the GH-IGF-I axis in farmed fish Open
Somatic growth in vertebrates is mainly controlled by the growth hormone (GH)/insulin-like growth factor I (IGF-I) axis. The role of epigenetic mechanisms in regulating this axis in fish is far from being understood. This work aimed to opt…
View article: Feeding and water temperature modulate the potential activity of gut microbiota in greater amberjack juveniles (Seriola dumerili)
Feeding and water temperature modulate the potential activity of gut microbiota in greater amberjack juveniles (Seriola dumerili) Open
Gut microbial communities are highly dynamic and respond to factors such as diet and host metabolism. However, there is limited knowledge on changes in gut microbiota during the daily cycle. To investigate how interactions between feeding …
View article: Data from: Feeding and water temperature modulate the activity of gut microbiota in greater amberjack juveniles (Seriola dumerili)
Data from: Feeding and water temperature modulate the activity of gut microbiota in greater amberjack juveniles (Seriola dumerili) Open
Illumina (MiSeq v3) sequencing data for gut microbiota profiling in greater amberjack (Seriola dumerili) juveniles reared at three different water temperatures and sampled along a day cycle.
View article: Data from: Feeding and water temperature modulate the activity of gut microbiota in greater amberjack juveniles (Seriola dumerili)
Data from: Feeding and water temperature modulate the activity of gut microbiota in greater amberjack juveniles (Seriola dumerili) Open
Illumina (MiSeq v3) sequencing data for gut microbiota profiling in greater amberjack (Seriola dumerili) juveniles reared at three different water temperatures and sampled along a day cycle.
View article: Biochemical features and modulation of digestive enzymes by environmental temperature in the greater amberjack, Seriola dumerili
Biochemical features and modulation of digestive enzymes by environmental temperature in the greater amberjack, Seriola dumerili Open
The study of fish digestive biochemistry is essential to understand factors that affect the net efficiency of food transformation and growth, and therefore aquaculture profitability. The aim of the present study was to assess the activity …
View article: Biotechnological treatment of microalgae enhances growth performance, hepatic carbohydrate metabolism and intestinal physiology in gilthead seabream (Sparus aurata) juveniles close to commercial size
Biotechnological treatment of microalgae enhances growth performance, hepatic carbohydrate metabolism and intestinal physiology in gilthead seabream (Sparus aurata) juveniles close to commercial size Open
The aim of this work was to evaluate the effects on growth performance, intermediary metabolism and welfare of the inclusion of two commercial microalgae-based ingredients called LB-ChromaBream (LB-CB) and LB-ChromaBream-plus (LB-CBplus) i…
View article: Feed Supplementation with the GHRP-6 Peptide, a Ghrelin Analog, Improves Feed Intake, Growth Performance and Aerobic Metabolism in the Gilthead Sea Bream Sparus aurata
Feed Supplementation with the GHRP-6 Peptide, a Ghrelin Analog, Improves Feed Intake, Growth Performance and Aerobic Metabolism in the Gilthead Sea Bream Sparus aurata Open
The aquaculture sector has experienced rapid and important growth with the subsequent increase of feeding and nutritional issues for sustaining this activity, mainly related to the use of high quality, safe and environmentally friendly fee…
View article: Toward a More Comprehensive View of α-Amylase across Decapods Crustaceans
Toward a More Comprehensive View of α-Amylase across Decapods Crustaceans Open
Decapod crustaceans are a very diverse group and have evolved to suit a wide variety of diets. Alpha-amylases enzymes, responsible for starch and glycogen digestion, have been more thoroughly studied in herbivore and omnivore than in carni…
View article: Toward a More Comprehensive View of α-Amylase across Decapods Crustaceans: New Insights from Carnivorous
Toward a More Comprehensive View of α-Amylase across Decapods Crustaceans: New Insights from Carnivorous Open
Decapod crustaceans are a very diverse group and have evolved to suit a wide variety of diets. Alpha-amylases enzymes, responsible for starch and glycogen digestion, have been more thoroughly studies in herbivore and omnivore than in carni…
View article: Effects of genetics and early-life mild hypoxia on size variation in farmed gilthead sea bream (Sparus aurata)
Effects of genetics and early-life mild hypoxia on size variation in farmed gilthead sea bream (Sparus aurata) Open
The present study evaluated, in an 18-month gilthead sea bream trial, the time course effects of genetics on individual size variation and growth compensation processes in families selected by heritable growth in the PROGENSA® breeding pro…
View article: Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream
Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream Open
Background: The key effects of intestinal microbiota in animal health has led to an increasing interest in manipulating these bacterial populations to improve animal welfare. The aquaculture sector is no exception and in the last years man…
View article: Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream
Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream Open
Background The key effects of intestinal microbiota in animal health has led to an increasing interest in manipulating these bacterial populations to improve animal welfare. The aquaculture sector is no exception and in the last years many…
View article: Additional file 6 of Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream
Additional file 6 of Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream Open
Additional file 6: Table S3. Piphillin inferred KEGG pathways significantly different (Padj < 0.05) between diet groups within each group of families (A: fast-growth suprafamily e5e6; B: intermediate-growth family c2c7; C: slow-growth supr…
View article: Crustacean Proteases and Their Application in Debridement
Crustacean Proteases and Their Application in Debridement Open
Digestive proteases from marine organisms have been poorly applied to
\nbiomedicine. Exceptions are trypsin and other digestive proteases from a few cold-adapted
\nor temperate fish and crustacean species. These enzymes are more efficient …
View article: Additional file 5 of Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream
Additional file 5 of Genetic selection for growth drives differences in intestinal microbiota composition and parasite disease resistance in gilthead sea bream Open
Additional file 5: Table S2. OTUs with minimum VIP values responsible of the separation of samples by diet in the different groups of families (A: fast-growth suprafamily e5e6; B: intermediate-growth family c2c7; C: slow-growth suprafamily…
View article: Effects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspring
Effects of Dietary Lipid Composition and Fatty Acid Desaturase 2 Expression in Broodstock Gilthead Sea Bream on Lipid Metabolism-Related Genes and Methylation of the fads2 Gene Promoter in Their Offspring Open
Polyunsaturated fatty acids (PUFA) in parental diets play a key role in regulating n-3 LC-PUFA metabolism of the offspring. However, it is not clear whether this metabolic regulation is driven by the precursors presented in the diet or by …
View article: Stearoyl-CoA desaturase (<i>scd1a</i>) is epigenetically regulated by broodstock nutrition in gilthead sea bream (<i>Sparus aurata</i>)
Stearoyl-CoA desaturase (<i>scd1a</i>) is epigenetically regulated by broodstock nutrition in gilthead sea bream (<i>Sparus aurata</i>) Open
The aim of this study was to generate new knowledge on fish epigenetics, assessing the effects of linolenic acid (ALA) conditioning of broodstock in the offspring of the marine fish Sparus aurata. Attention was focused on gene organization…
View article: Age- and season-mediated changes in DNA Methylation and expression patterns of sirtuins in gilthead sea bream Sparus aurata
Age- and season-mediated changes in DNA Methylation and expression patterns of sirtuins in gilthead sea bream Sparus aurata Open
Sirtuins (SIRTs) are a conserved family of enzymes that couple protein deacetylation of histone and non-histone substrates with the energy status of the cell via the cellular NAD+/NADH ratio. This protein family has been largely conserved …