Erik A. H. Loeffen
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View article: Topical analgesia during needle-related procedures in children: a clinical practice guideline
Topical analgesia during needle-related procedures in children: a clinical practice guideline Open
During intensive and long-lasting treatments, short-term or emergency care, children often undergo minor needle-related procedures (ie, venepuncture, venous cannulation and puncture of central venous access ports). The use of topical analg…
View article: Prophylactic red blood cell transfusions in children and neonates with cancer: An evidence-based clinical practice guideline
Prophylactic red blood cell transfusions in children and neonates with cancer: An evidence-based clinical practice guideline Open
View article: Obtaining first-line induction in autoimmune hepatitis: Aren’t we underestimating prednisolone?
Obtaining first-line induction in autoimmune hepatitis: Aren’t we underestimating prednisolone? Open
View article: Less restrictions in daily life: a clinical practice guideline for children with cancer
Less restrictions in daily life: a clinical practice guideline for children with cancer Open
Purpose In current clinical practice, recommendations regarding restrictions in daily life for children with cancer are often lacking or not evidence-based. Critically reviewing the evidence and formulating recommendations are therefore of…
View article: Fetal–neonatal exposure to antibiotics and NEC development: A systematic review and meta-analysis
Fetal–neonatal exposure to antibiotics and NEC development: A systematic review and meta-analysis Open
Background Fetal and neonatal exposure to antibiotics may contribute to the development of necrotizing enterocolitis (NEC) in preterm infants. This systematic review and meta-analysis investigate whether exposure to third trimester materna…
View article: Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
Communication and ethical considerations for fertility preservation for patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group Open
View article: Fertility preservation for female patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
Fertility preservation for female patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group Open
View article: Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group
Fertility preservation for male patients with childhood, adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group Open
View article: Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action
Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action Open
View article: Reducing pain and distress related to needle procedures in children with cancer: A clinical practice guideline
Reducing pain and distress related to needle procedures in children with cancer: A clinical practice guideline Open
View article: Treatment-related mortality in children with cancer: Prevalence and risk factors
Treatment-related mortality in children with cancer: Prevalence and risk factors Open
View article: Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline
Reducing pain in children with cancer: Methodology for the development of a clinical practice guideline Open
Although pain is one of the most prevalent and bothersome symptoms children with cancer experience, evidence‐based guidance regarding assessment and management is lacking. With 44 international, multidisciplinary healthcare professionals a…
View article: Measurement properties of instruments to assess pain in children and adolescents with cancer: a systematic review protocol
Measurement properties of instruments to assess pain in children and adolescents with cancer: a systematic review protocol Open
View article: Perfect pitstops: Towards evidence-based supportive care in children with cancer
Perfect pitstops: Towards evidence-based supportive care in children with cancer Open
In de afgelopen decennia is er enorme vooruitgang geboekt in de behandeling van kinderkanker, waardoor momenteel ruim drie op de vier kinderen genezen van deze ziekte. Toch gaan er nog kinderen met kanker dood; de meeste door de ziekte zel…
View article: Development of pediatric oncology supportive care indicators: Evaluation of febrile neutropenia care in the north of the Netherlands
Development of pediatric oncology supportive care indicators: Evaluation of febrile neutropenia care in the north of the Netherlands Open
Introduction Febrile neutropenia (FN) is a common complication of the intensive treatment strategies used in pediatric oncology. By close adherence to high‐quality guidelines, which can be evaluated by indicators, the burden of FN can pote…
View article: Predictive value of PCT and IL-6 for bacterial infection in children with cancer and febrile neutropenia
Predictive value of PCT and IL-6 for bacterial infection in children with cancer and febrile neutropenia Open
View article: Individualised advance care planning in children with life-limiting conditions
Individualised advance care planning in children with life-limiting conditions Open
Introduction In 2013, the Pediatric Association of the Netherlands launched an evidence-based guideline ‘Palliative care for children’. To promote implementation in daily practice and hereby improve quality of paediatric palliative care, w…
View article: The duration of anthracycline infusion should be at least one hour in children with cancer: A clinical practice guideline
The duration of anthracycline infusion should be at least one hour in children with cancer: A clinical practice guideline Open
We aimed to provide recommendations on the infusion duration of anthracycline chemotherapy agents in children with cancer. This study also serves as a practice example of the essential steps that need to be taken when using a previously pu…
View article: Patients’ and parents’ views regarding supportive care in childhood cancer
Patients’ and parents’ views regarding supportive care in childhood cancer Open
View article: The importance of evidence-based supportive care practice guidelines in childhood cancer—a plea for their development and implementation
The importance of evidence-based supportive care practice guidelines in childhood cancer—a plea for their development and implementation Open
View article: Fertility preservation in children, adolescents, and young adults with cancer: Quality of clinical practice guidelines and variations in recommendations
Fertility preservation in children, adolescents, and young adults with cancer: Quality of clinical practice guidelines and variations in recommendations Open
BACKGROUND Fertility preservation care for children, adolescents, and young adults (CAYAs) with cancer is not uniform among practitioners. To ensure high‐quality care, evidence‐based clinical practice guidelines (CPGs) are essential. The a…
View article: Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia
Very early discharge versus early discharge versus non-early discharge in children with cancer and febrile neutropenia Open
Very limited data were available regarding the safety of early discharge compared to non-early discharge from in-hospital treatment in children with cancer and febrile neutropenia and a low risk for invasive infection. The absence of clear…
View article: Current variations in childhood cancer supportive care in the <scp>N</scp>etherlands
Current variations in childhood cancer supportive care in the <span>N</span>etherlands Open
BACKGROUND Current treatment strategies in pediatric oncology are intensive and lead to high survival rates but also to treatment‐related complications. Therefore, supportive care plays an increasingly important role. This study was design…