Erik Hyllner
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View article: Antigen affinity and site of immunization dictate B cell recall responses
Antigen affinity and site of immunization dictate B cell recall responses Open
Summary Protective antibodies against HIV-1 require unusually high levels of somatic hypermutations (SHMs) introduced in germinal centers (GCs). To achieve this, a sequential vaccination approach was proposed. Using HIV-1 antibody knock-in…