Erika Gebel Berg
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View article: Immunohistochemical Analysis of Nicotinamide Phosphoribosyltransferase Expression in Gastric and Esophageal Adenocarcinoma (AEG)
Immunohistochemical Analysis of Nicotinamide Phosphoribosyltransferase Expression in Gastric and Esophageal Adenocarcinoma (AEG) Open
Nicotinamide phosphoribosyltransferase (NAMPT) represents a major component in cellular energy metabolism, which is also crucial for cancer cells that have elevated aerobic glycolysis; moreover, targeting the NAD salvage pathway by inhibit…
View article: Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas
Prognostic impact of activin subunit inhibin beta A in gastric and esophageal adenocarcinomas Open
View article: Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas
Inhibition of MACC1-Induced Metastasis in Esophageal and Gastric Adenocarcinomas Open
Esophageal and Gastric Adenocarcinomas (AGE/S) are characterized by early metastasis and poor survival. MACC1 (Metastasis Associated in Colon Cancer 1) acts in colon cancer as a metastasis inducer and is linked to reduced survival. This pr…
View article: S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus
S100A4 Is a Strong Negative Prognostic Marker and Potential Therapeutic Target in Adenocarcinoma of the Stomach and Esophagus Open
Deregulated Wnt-signaling is a key mechanism driving metastasis in adenocarcinoma of the gastroesophageal junction and stomach (AGE/S). The oncogene S100A4 was identified as a Wnt-signaling target gene and is known to promote metastasis. I…
View article: Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies
Response prediction in patients with gastric and esophagogastric adenocarcinoma under neoadjuvant chemotherapy using targeted gene expression analysis and next-generation sequencing in pre-therapeutic biopsies Open
View article: Prognostic Impact of Activin in Gastric and Esophageal Adenocarcinomas
Prognostic Impact of Activin in Gastric and Esophageal Adenocarcinomas Open
Purpose:Adenocarcinomas of the esophagus (AEG) and stomach (AS) are among the most common cancers worldwide. Novel markers for risk stratification and guiding treatment are strongly needed. Activin is a multi-functional cytokine with conte…
View article: Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL
Evidence for a role of RUNX1 as recombinase cofactor for TCRβ rearrangements and pathological deletions in ETV6-RUNX1 ALL Open
T-cell receptor gene beta (TCRβ) gene rearrangement represents a complex, tightly regulated molecular mechanism involving excision, deletion and recombination of DNA during T-cell development. RUNX1, a well-known transcription factor for T…
View article: Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas
Prognostic impact of Claudin 18.2 in gastric and esophageal adenocarcinomas Open
View article: Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression
Better prognosis of gastric cancer patients with high levels of tumor infiltrating lymphocytes is counteracted by PD-1 expression Open
The prognostic potential of anti-tumor immune responses is becoming increasingly important in adenocarcinoma of the gastroesophageal junction and stomach (AGE/S) especially regarding the use of immune checkpoint inhibitors. This study anal…
View article: <p>Bortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesothelioma</p>
Bortezomib sensitivity is tissue dependent and high expression of the 20S proteasome precludes good response in malignant pleural mesothelioma Open
NCT00513877 and NCT00458913.
View article: Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma
Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma Open
View article: Additional file 3: of Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma
Additional file 3: of Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma Open
File S3. RNA-Seq data of differentially expressed genes derived from comparison of BL vs. DLBCL, BL vs. DLBCLneg, DLBCLneg vs. DLBCLpos and BL vs. DLBCLpos. (XLSX 13003 kb)
View article: Additional file 2: of Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma
Additional file 2: of Identification of ADGRE5 as discriminating MYC target between Burkitt lymphoma and diffuse large B-cell lymphoma Open
File S2. ChIP-Seq data of differentially bound MYC and H3K4 target genes derived from comparison of BL vs. DLBCL, BL vs. DLBCLneg, DLBCLneg vs. DLBCLpos and BL vs. DLBCLpos. (XLSX 1673 kb)
View article: Diabetes Technology Society Report on the FDA Digital Health Software Precertification Program Meeting
Diabetes Technology Society Report on the FDA Digital Health Software Precertification Program Meeting Open
Diabetes Technology Society (DTS) convened a meeting about the US Food and Drug Administration (FDA) Digital Health Software Precertification Program on August 28, 2018. Forty-eight attendees participated from clinical and academic endocri…
View article: Immunohistochemical Study of Mitosis-regulatory Proteins in Gastroenteropancreatic Neuroendocrine Neoplasms
Immunohistochemical Study of Mitosis-regulatory Proteins in Gastroenteropancreatic Neuroendocrine Neoplasms Open
The expression of aurora kinase B is associated with differentiation, progression and the aggressiveness of GEP-NENs. In the context of tumor progression, aurora B is strongly associated with markers of the mitosis regulatory network, surv…
View article: American Diabetes Association’s Standards of Care: A Paradigm Shift in the Dissemination of Information
American Diabetes Association’s Standards of Care: A Paradigm Shift in the Dissemination of Information Open
It is well understood that diabetes is a complex, chronic illness in which glycemic control reduces the development and progression of macrovascular and microvascular complications. Achieving risk reduction requires continuous medical care…
View article: Lessons in Care: Insights Into Recent Changes in the American Diabetes Association’s Clinical Practice Recommendations
Lessons in Care: Insights Into Recent Changes in the American Diabetes Association’s Clinical Practice Recommendations Open
In January, the American Diabetes Association (ADA) published the Standards of Medical Care in Diabetes—2017 (1), its comprehensive evidence-based clinical practice recommendations for the care of people with or at risk for diabetes. The S…
View article: A Conversation with Sascha Drewlo
A Conversation with Sascha Drewlo Open
ADVERTISEMENT RETURN TO ISSUEPREVCenter StageNEXTA Conversation with Sascha DrewloThe molecular biologist applies genomics to challenging questions about pregnancy health.Erika Gebel BergCite this: ACS Cent. Sci. 2017, 3, 1, 3–4Publication…
View article: Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas
Poorly Differentiated Medullary Phenotype Predicts Poor Survival in Early Lymph Node-Negative Gastro-Esophageal Adenocarcinomas Open
In the presented study patients with AGE/S in stage UICC-I-N0 had a better prognosis as previously reported for Caucasian patients. Poorly differentiated medullary subtype was associated with reduced survival and should be considered when …
View article: Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities
Youth-Onset Type 2 Diabetes Consensus Report: Current Status, Challenges, and Priorities Open
Type 2 diabetes is a significant and increasing burden in adolescents and young adults. Clear strategies for research, prevention, and treatment of the disease in these vulnerable patients are needed. Evidence suggests that type 2 diabetes…
View article: Designer Drug Detective Work
Designer Drug Detective Work Open
ADVERTISEMENT RETURN TO ISSUEPREVThe HubNEXTDesigner Drug Detective WorkScientists race to understand the neurochemistry behind new street drugs.Erika Gebel BergCite this: ACS Cent. Sci. 2016, 2, 6, 363–366Publication Date (Web):June 10, 2…
View article: Immunohistochemical study of AuroraB proves association with differentiation and expression of crucial progression markers in gastroenteropancreatic neuroendocrine neoplasms
Immunohistochemical study of AuroraB proves association with differentiation and expression of crucial progression markers in gastroenteropancreatic neuroendocrine neoplasms Open
Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)
View article: A Conversation with Eric Breitung
A Conversation with Eric Breitung Open
ADVERTISEMENT RETURN TO ISSUEPREVCenter StageNEXTA Conversation with Eric BreitungThe conservation expert applies his knowledge of chemistry and materials science to preserving works of art.Erika Gebel BergCite this: ACS Cent. Sci. 2016, 2…
View article: Breaking the Crystal Ceiling
Breaking the Crystal Ceiling Open
ADVERTISEMENT RETURN TO ISSUEPREVThe HubNEXTBreaking the Crystal CeilingCryo-electron microscopy goes high resolution.Erika Gebel BergCite this: ACS Cent. Sci. 2015, 1, 6, 283–285Publication Date (Web):September 8, 2015Publication History …
View article: The Chemistry of the Pill
The Chemistry of the Pill Open
ADVERTISEMENT RETURN TO ISSUEPREVThe HubNEXTThe Chemistry of the PillErika Gebel BergCite this: ACS Cent. Sci. 2015, 1, 1, 5–7Publication Date (Web):March 23, 2015Publication History Published online23 March 2015Published inissue 25 March …
View article: FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors
FOXM1: A novel drug target in gastroenteropancreatic neuroendocrine tumors Open
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) are heterogeneous tumors that need to be molecularly defined to obtain novel therapeutic options. Forkheadbox protein M1 (FOXM1) is a crucial transcription factor in neoplastic cel…