Explanipedia

Clinical Course and Autopsy of a 70-Year-Old Woman With Double-Inlet Left Ventricle Open

Kaori Murakawa, Ayumi Omuro, Seigo Okada, Yusuke Nakashima, Takeshi Suetomi , et al. · 2025

This case exemplifies a rare congenital heart disease. The detailed autopsy results significantly enhance understanding of the condition's natural history and clinical course.

A Pheochromocytoma With Adrenocorticotropic Hormone Secretion and Subsequent Fatal Outcome: A Case Report Open

Hiroko Nakabayashi, Masaru Akiyama, Takuma Yodokawa, Wataru Ito, Akihiko Taguchi , et al. · 2025

Characterizing soluble immune checkpoint molecules and TGF-β1,2,3 in pleural effusion of malignant pleural mesothelioma Open

Riki Okita, Tomoya Senoo, Yuka Mimura‐Kimura, Yusuke Mimura, Tomoyuki Murakami , et al. · 2024

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Koji Arihiro, Atsushi Enomoto, Satoshi Fujii, Noriyoshi Fukushima, Hideki Hasegawa , et al. · 2024

Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…

Characterizing soluble immune checkpoint molecules and TGF-β 1,2,3 in pleural effusion of malignant pleural mesothelioma Open

Riki Okita, Tomoya Senoo, Yuka Mimura‐Kimura, Yusuke Mimura, Tomoyuki Murakami , et al. · 2024

The clinical impact of soluble molecules in pleural effusion (PE) is unclear in patients with malignant pleural mesothelioma (MPM). In this single-center, retrospective, observational study, we assessed soluble forms of cytotoxic T-lymphoc…

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Koji Arihiro, Atsushi Enomoto, Satoshi Fujii, Noriyoshi Fukushima, Hideki Hasegawa , et al. · 2024

Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…

Congenital Pulmonary Lymphangiectasia Masked by Postoperative Pulmonary Venous Obstruction in an Infant with Total Anomalous Pulmonary Venous Connection Open

Yoshiko Nawata, Daisuke Toyomura, Seigo Okada, Yasuo Suzuki, Narumi Honda-Nakada , et al. · 2024

Congenital pulmonary lymphangiectasia (CPL) is associated with fetal pulmonary venous obstructive physiology. The precise morbidity of CPL is unknown as CPL is generally fatal in neonates. Here, we report an infant with secondary CPL in to…

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Koji Arihiro, Atsushi Enomoto, Satoshi Fujii, Noriyoshi Fukushima, Hideki Hasegawa , et al. · 2024

Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…

ANALYSIS OF ATTITUDES TOWARD STAYING IN THE CITY CENTER BEFORE AND AFTER WATCHING J-LEAGUE GAMES Open

Eiji Ikeda, Yu SUZUKI, Shintaro TERABE, Hideki YAGINUMA, Haruka UNO · 2024

ANALYSIS OF STAY BEFORE AND AFTER WATCHING J-LEAGUE GAMES USING LOCATION INFORMATION OF VARIOUS CELL PHONES Open

Eiji Ikeda, Yu SUZUKI, Shintaro TERABE, Hideki YAGINUMA · 2024

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Koji Arihiro, Atsushi Enomoto, Satoshi Fujii, Noriyoshi Fukushima, Hideki Hasegawa , et al. · 2024

Wiley's Corporate Citizenship initiative seeks to address the environmental, social, economic, and ethical challenges faced in our business and which are important to our diverse stakeholder groups.Since launching the initiative, we have f…

A case of primary lung adenocarcinoma mimicking metastatic papillary thyroid carcinoma Open

Akira Tanaka, Riki Okita, Takushi Morishige, Masanori Okada, Hidetoshi Inokawa , et al. · 2023

A 61‐year‐old woman, who had a history of total thyroidectomy for follicular variant of papillary thyroid carcinoma (PTC), visited our hospital for assessment of an enlarging nodule which appeared in the lung with multiple metastatic lesio…

Optimal Case Selection and Required Experience in Training for Elective Laparoscopic Cholecystectomy among Surgery Residents Open

Kazuya Moriwake, Takashi Kuise, Tomohiro Hamazaki, Shunsuke Nakamura, Asuka Mimata , et al. · 2023

目的：外科専攻医が安全に待機的腹腔鏡下胆囊摘出術（laparoscopic cholecystectomy；以下，LCと略記）を執刀し修練認定を得るために必要な症例数と適切な執刀症例選択の指標について検討する．方法：2018年4月から2021年12月の期間に当科専攻医5名が執刀した待機的LC症例124例を対象とした．それぞれの専攻医の手術時間について累積和（cumulative sum；以下，CUSUMと略記）法を用いてラーニングカーブを作成し習熟に必要な症例数について検討…

Open surgical treatment for aortic arch and coronary artery aneurysms associated with immunoglobulin G4-related disease: a case report Open

Toshiki Yokoyama, Ryo Suzuki, Hiroshi Kurazumi, Akira Tanaka, Hiroo Kawano , et al. · 2023

Background Immunoglobulin G4-related disease (IgG4RD) is a systemic autoimmune disease characterized by a dense lymphoplasmacytic infiltrate containing IgG4-positive plasma cells that can cause aneurysms in various organs and tissues. Ther…

Preoperative neutrophil-to-lymphocyte ratio correlates with PD-L1 expression in immune cells of patients with malignant pleural mesothelioma and predicts prognosis Open

Riki Okita, Nobutaka Kawamoto, Masanori Okada, Hidetoshi Inokawa, Naoki Yamamoto , et al. · 2023

A case of development of autoimmune pulmonary alveolar proteinosis during the treatment of hypersensitivity pneumonitis Open

Maki Asami‐Noyama, Kosuke Ito, Misa Harada, Yukari Hisamoto, Yoshie Kunihiro , et al. · 2023

Herein, we report the case of a 73-year-old woman with an occupational history of plaster grinding who developed autoimmune pulmonary alveolar proteinosis (PAP) during the treatment of fibrotic hypersensitivity pneumonitis with steroids an…

Correction: Expression of ADAM15 in rheumatoid synovium: up-regulation by vascular endothelial growth factor and possible implications for angiogenesis Open

Koichiro Komiya, Hiroyuki Enomoto, Isao Inoki, Satoko Okazaki, Yoshinari Fujita , et al. · 2022

Expert perspectives on pathological findings in vasculitis Open

Akihiro Ishizu, Tamihiro Kawakami, Hiroyuki Kanno, Kei Takahashi, Tatsuhiko Miyazaki , et al. · 2022

Pathological findings are important in the diagnosis of vasculitis. However, due to the rarity of the disease, standard textbooks usually devote only a few pages to this topic, and this makes it difficult for clinicians not specializing in…

Intravenous injection of cyclophilin A realizes the transient and reversible opening of barrier of neural vasculature through basigin in endothelial cells Open

Narumi Nakada-Honda, Dan Cui, Satoshi Matsuda, Eiji Ikeda · 2021

Neural vasculature forms the blood–brain barrier against the delivery of systemically administered therapeutic drugs into parenchyma of neural tissues. Therefore, procedures to open the blood–brain barrier with minimal damage to tissues wo…

Investigation of histological heterogeneity based on the discrepancy between the hyperintense area on T2-weighted images and the accumulation area on 11C-methionine PET in minimally enhancing glioma Open

Makoto Ideguchi, Takafumi Nishizaki, Norio Ikeda, Natsumi Fujii, Machiko Ohno , et al. · 2021

Three Cases of Anorectal Malignant Melanoma Treated with Laparoscopic Abdominoperineal Resection Open

Shin Yoshida, Nobuaki Suzuki, Shinobu Tomochika, Yoshitaro Shindo, Yukio Tokumitsu , et al. · 2021

腹腔鏡下腹会陰式直腸切断術を施行した直腸肛門部悪性黒色腫(anorectal malignant melanoma;以下,AMMと略記)の3例を経験した.症例1は73歳の女性で,主訴は下血であった.大腸癌取扱い規約第9版に準じるとpT1bN2aM0であり,術後補助療法を行った.術後4か月で側方リンパ節転移を認めた.症例2は,血液透析中の45歳の男性で,主訴は肛門部腫瘤であった.pT2N1bM0であり,術後補助療法は行わなかった.術後2か月で鼠経リンパ節転移を認めた.症例3は…

Suspected fibrin glue‐induced acute eosinophilic pneumonia after pulmonary resection: A case report Open

Nobutaka Kawamoto, Riki Okita, Masataro Hayashi, Masanori Okada, Kosuke Ito , et al. · 2021

Air leakage is a common complication after pulmonary resection, and fibrin glue is used as a sealant to reduce postoperative air leakage. It is generally recognized that fibrin glue‐induced adverse events are rare. Herein, we report a rare…

Autologous Multilayered Fibroblast Sheets Can Reinforce Bronchial Stump in a Rat Model Open

Sota Yoshimine, Koji Ueno, Junichi Murakami, Toshiro Saito, Ryo Suzuki , et al. · 2021

Islet cell dedifferentiation is a pathologic mechanism of long-standing progression of type 2 diabetes Open

Kikuko Amo-Shiinoki, Katsuya Tanabe, Yoshinobu Hoshii, Hiroto Matsui, Risa Harano , et al. · 2021

Dedifferentiation has been implicated in β cell dysfunction and loss in rodent diabetes. However, the pathophysiological significance in humans remains unclear. To elucidate this, we analyzed surgically resected pancreatic tissues of 26 Ja…

A Study on the Causal Relationship between “the Flow of a Game” and Its Outcome in Basketball: Focusing on the Interdependence Relations of Four Periods* Open

Haruki Uchiyama, Eiji Ikeda, Kenji Yoshida, Yosuke Machida, Tomoo Amino , et al. · 2021

The purpose of this study was to clarify the causal relationship between the “flow of a game” that can be defined “the situation on which 4 periods which consist of division time as 10 minutes are advancing gradually while having an influe…

A Case of Idiopathic Perforation in the Stoma Limb 19 years after Colostomy Open

Shunsuke Nakamura, Masatoshi Kuroda, Kiyoto Takehara, Eiji Ikeda · 2021

症例：91歳，女性．主訴：腹痛．現病歴：強い腹痛を主訴に前医を受診し，消化管穿孔に伴う汎発性腹膜炎が疑われ，手術目的に当院紹介となった．既往歴：直腸癌（Hartmann手術：72歳）．意識清明．血圧116/58mmHg，HR68回/分．ストーマ周囲に反跳痛を伴う強い圧痛あり．腹部CT：ストーマ周囲の腹壁内に便塊と腸管外ガスを認め,人工肛門脚部穿孔と診断し緊急手術を施行した．術中所見でS状結腸間膜側に約20mm径の穿孔を認めたが，糞便は間膜内に限局しており，腹壁内に便の流出は…

Eyes Closing and Drowsiness in Human Subjects Decrease Baseline Galvanic Skin Response and Active Palmar Sweating: Relationship Between Galvanic Skin and Palmar Perspiration Responses Open

Hideya Momose, Norimasa Morimitsu, Eiji Ikeda, Shigeki Kanai, Masao Sakaguchi , et al. · 2020

We previously constructed a perspiration ratemeter for the measurement of palmar sweating in human subjects. Although galvanic skin response (GSR) has been used to evaluate emotional responses in human subjects, little is known about the r…

Treatment strategy for primary lung cancer in a lung highly compressed by giant emphysematous bullae: A case report Open

Nobutaka Kawamoto, Masataro Hayashi, Riki Okita, Masanori Okada, Hidetoshi Inokawa , et al. · 2020

Lung cancer sometimes develops on the wall of a giant emphysematous bulla (GEB). Herein, we describe a rare case in which lung cancer developed in lung tissue compressed by GEBs. A 62‐year‐old man underwent a computed tomography (CT) scan …

Diagnostic and therapeutic role of endoscopic retrograde pancreatography and stent placement for grade IV blunt pancreatic trauma: A case report Open

Dai Shimizu, Toshihisa Yamano, Yasutaka Kudo, Masatoshi Kuroda, Shoji Takagi , et al. · 2020

A Case of Anastomotic Recurrence 6 Years and 7 Months after Functional End-to-End Anastomosis Performed for Transverse Colon Cancer Open

Masatoshi Kuroda, Eiji Ikeda, Kiyoto Takehara · 2020

症例は79歳，女性．腹痛を主訴に受診し，横行結腸癌の診断に至り腹腔鏡下左半結腸切除術（D3郭清）を施行した．吻合は機能的端々吻合で行った．病理検査はtub2，SS，N1，M0，stageIIIaであった．術後9ヵ月目に肝転移，術後1年目に肺転移が出現しそれぞれ手術を施行した．術後6年目に腹壁瘢痕ヘルニア修復術の術前精査で深部静脈血栓症を認めたために術後より抗凝固療法を開始した．抗凝固療法開始後内服2ヵ月後より下血，貧血を呈したために下部消化管内視鏡検査を施行し，吻合部に腫瘍…

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