Erin D. Michos
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View article: Randomized Comparison of Online Motivational Themes in Clinical Trial Recruitment
Randomized Comparison of Online Motivational Themes in Clinical Trial Recruitment Open
Background: Targeted, digital recruitment strategies like tailored websites using motivational themes may improve recruitment in clinical trials, but their effectiveness remains unclear. We hypothesized that themes emphasizing community we…
View article: Cardiovascular Multimorbidity in Older Adults in the United States by Race and Sex
Cardiovascular Multimorbidity in Older Adults in the United States by Race and Sex Open
View article: Evaluating the Science of Diversity in Clinical Trials: Design and Goals of an American Heart Association Strategic Focused Research Network
Evaluating the Science of Diversity in Clinical Trials: Design and Goals of an American Heart Association Strategic Focused Research Network Open
Background Clinical trials serve as the key evidence that shapes guideline recommendations and clinical practice. Despite long‐standing recommendations by regulatory and funding organizations for representative trial enrollment, the underi…
View article: Comorbidities and Pregnancy-Related Risk Factors in Patients with Severe Maternal Morbidity: Application of a Validated Obstetrical Comorbidity Scoring System to a Surveillance-Identified Population
Comorbidities and Pregnancy-Related Risk Factors in Patients with Severe Maternal Morbidity: Application of a Validated Obstetrical Comorbidity Scoring System to a Surveillance-Identified Population Open
Background/Objectives: Patient characteristics—especially comorbidities—influence the risk of severe maternal morbidity (SMM). Recent efforts have sought to derive an obstetric comorbidity score to be used for case-mix adjustment. We asses…
View article: Heterogeneity of effect of Intensive lifestyle intervention on cardiometabolic risk factors by sex hormones in diabetes
Heterogeneity of effect of Intensive lifestyle intervention on cardiometabolic risk factors by sex hormones in diabetes Open
Background Intensive lifestyle intervention(ILI) in type 2 diabetes(T2D) improves cardiometabolic risk factors. Sex differences in these responses may be driven by the sex hormones testosterone(T), estradiol(E2), and sex hormone binding gl…
View article: The continuum of prevention and heart failure in cardiovascular medicine: A joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology
The continuum of prevention and heart failure in cardiovascular medicine: A joint scientific statement from the Heart Failure Society of America and the American Society for Preventive Cardiology Open
Heart disease is the leading cause of death worldwide, with heart failure (HF) recognized as its most severe and debilitating manifestation. Though remarkable advancements have led to the establishment of life-saving and quality-of-life-en…
View article: Sex differences in guideline-based statin utilization and recurrent events in patients with known coronary artery disease
Sex differences in guideline-based statin utilization and recurrent events in patients with known coronary artery disease Open
View article: Blood pressure reduction by gender and menopause status among hypertensive participants of a mobile health cardiovascular risk self-management program
Blood pressure reduction by gender and menopause status among hypertensive participants of a mobile health cardiovascular risk self-management program Open
There were clinically meaningful reductions in BP among participants of an mHealth app, with women showing greater BP reductions than men. Findings suggest that targeted, sex-specific health information and digital coaching can be effectiv…
View article: US Public Health Gains from Improved Treatment of Hypercholesterolemia: A Simulation Study of NHANES Adults Treated to Guideline-Directed Therapy
US Public Health Gains from Improved Treatment of Hypercholesterolemia: A Simulation Study of NHANES Adults Treated to Guideline-Directed Therapy Open
Importance Hypercholesterolemia is widely undertreated. Objective To project anticipated improvements in treatment and outcomes under full implementation of US and European pharmacologic treatment recommendations. Design, Setting, and Part…
View article: Genome-wide association study of angiotensinogen levels and key single nucleotide polymorphism associations with blood pressure
Genome-wide association study of angiotensinogen levels and key single nucleotide polymorphism associations with blood pressure Open
Objective: The renin angiotensin aldosterone system plays a key role in circulatory homeostasis. We sought to identify genetic determinants of measured plasma angiotensinogen levels and subsequently evaluate the association of these single…
View article: Quantifying the impact of early-life growth adversity on later-life health
Quantifying the impact of early-life growth adversity on later-life health Open
Background Early-life growth adversity is important to later-life health, but precision assessment in adulthood is challenging. We evaluated whether the difference between attained and genotype-predicted adult height (“height-GaP”) would a…
View article: Baseline Cardiac Biomarker Levels as Predictors of Cancer Risk in the MESA Cohort
Baseline Cardiac Biomarker Levels as Predictors of Cancer Risk in the MESA Cohort Open
In the MESA cohort, higher baseline levels of hs-cTnT and NT-proBNP predicted an increased risk of incident cancer, with no significant differences by race/ethnicity or sex.
View article: Circulating Levels of Angiotensinogen, Sex Hormones, and Hormone Therapy—The Multi‐Ethnic Study of Atherosclerosis (MESA)
Circulating Levels of Angiotensinogen, Sex Hormones, and Hormone Therapy—The Multi‐Ethnic Study of Atherosclerosis (MESA) Open
Angiotensinogen, the unique precursor of all angiotensin hormones of the renin‐angiotensin‐aldosterone system (RAAS), is now a potential target in a novel pharmacological approach to hypertension. Investigating the factors that influence a…
View article: The Joint Association of Diet Quality and Sleep Regularity with Incident Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis
The Joint Association of Diet Quality and Sleep Regularity with Incident Cardiovascular Disease in the Multi-Ethnic Study of Atherosclerosis Open
Background/Objectives: Diet quality and sleep regularity both influence cardiovascular disease (CVD) risk and may influence each other, but there is scarce evidence for their joint or interacting associations in relation to CVD. We assesse…
View article: Predicting Mortality Risk Using the PREVENT Equation Across Diverse Racial Groups
Predicting Mortality Risk Using the PREVENT Equation Across Diverse Racial Groups Open
These study findings validate PREVENT scores across diverse racial and ethnic populations, highlighting the tool's effectiveness in predicting cardiovascular risk and mortality regardless of race or ethnicity.
View article: Cardiovascular disease risk factors in newly diagnosed rheumatoid arthritis: A retrospective cohort study
Cardiovascular disease risk factors in newly diagnosed rheumatoid arthritis: A retrospective cohort study Open
View article: Advocating for collaboration among key partners to promote diversity in clinical studies amid policy challenges in the United States of America
Advocating for collaboration among key partners to promote diversity in clinical studies amid policy challenges in the United States of America Open
The lack of diversity in clinical studies has significant ethical and health consequences, limiting the development of effective treatments for diverse populations. Homogeneous participation in clinical studies contributes to health dispar…
View article: Recognition and management of persistent chylomicronemia: A joint expert clinical consensus by the National Lipid Association and the American Society for Preventive Cardiology
Recognition and management of persistent chylomicronemia: A joint expert clinical consensus by the National Lipid Association and the American Society for Preventive Cardiology Open
View article: Proteomic Correlates of Vitamin D Supplementation in the Atherosclerosis Risk in Communities (ARIC) Study
Proteomic Correlates of Vitamin D Supplementation in the Atherosclerosis Risk in Communities (ARIC) Study Open
Purpose Proteins are key effectors of biological functions and play roles in signaling, transport, growth, repair, and immunity. Vitamin D biomarkers may be reflected in the plasma proteome. The aim of this discovery study was to identify …
View article: Epicardial Fat in Heart Failure and Preserved Ejection Fraction: Novel Insights and Future Perspectives
Epicardial Fat in Heart Failure and Preserved Ejection Fraction: Novel Insights and Future Perspectives Open
View article: Sex Hormones and Heart Failure Risk
Sex Hormones and Heart Failure Risk Open
Heart failure (HF) is a significant cause of morbidity and mortality. Although there are inconsistencies, epidemiological studies have implicated sex hormones (SHs) in pathways that are linked to HF. The age-related decline in SH levels ca…
View article: Recognition and management of persistent chylomicronemia: A joint expert clinical consensus by the National Lipid Association and the American Society for Preventive Cardiology
Recognition and management of persistent chylomicronemia: A joint expert clinical consensus by the National Lipid Association and the American Society for Preventive Cardiology Open
Extreme hypertriglyceridemia, defined as triglyceride (TG) levels ≥1000 mg/dL, is almost always indicative of chylomicronemia. The current diagnostic approach categorizes individuals with chylomicronemia into familial chylomicronemia syndr…
View article: Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias
Sodium-Glucose Cotransporter-2 Inhibitors and Arrhythmias Open
View article: County-level association between modifiable health behaviors and premature mortality in the United States
County-level association between modifiable health behaviors and premature mortality in the United States Open
We demonstrate an independent association of county-level physical inactivity, insufficient sleep, and current smoking with premature mortality. Further research and public health efforts are needed to understand and mitigate these risk fa…
View article: Kurzfassung der KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (Leitlinie für die klinische Praxis zur Diabetesbehandlung bei chronischer Nierenkrankheit): eine Aktualisierung auf Grundlage neuer Erkenntnisse
Kurzfassung der KDIGO 2022 Clinical Practice Guideline for Diabetes Management in Chronic Kidney Disease (Leitlinie für die klinische Praxis zur Diabetesbehandlung bei chronischer Nierenkrankheit): eine Aktualisierung auf Grundlage neuer Erkenntnisse Open
Die Kidney Disease: Improving Global Outcomes (KDIGO) 2022 Klinische Praxisrichtlinie für die Behandlung des Diabetes bei chronischer Nierenkrankheit (chronic kidney disease, CKD) stellt eine Aktualisierung der KDIGO-Leitlinie 2020 dar. Di…
View article: Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis
Cardiovascular Complications During Delivery Hospitalization in Patients With Psoriasis Open
Delivery hospitalizations in patients with psoriasis are associated with a higher risk of preeclampsia/eclampsia and cardiac arrhythmias.
View article: Motivation to Clinical Trial Participation: Health Information Distrust and Healthcare Access as Explanatory Variables and Gender as Moderator
Motivation to Clinical Trial Participation: Health Information Distrust and Healthcare Access as Explanatory Variables and Gender as Moderator Open
Background: There is significant underrepresentation in clinical trials across diverse populations. Less is known about how health system-related factors, such as relationships and trust, mediate the motivation for clinical trial participa…
View article: Coronary atherosclerosis in athletes: emerging concepts and preventive strategies
Coronary atherosclerosis in athletes: emerging concepts and preventive strategies Open
There should be no assumption that an athlete is immune to coronary artery disease (CAD), even when traditional cardiovascular (CV) risk factors appear well-managed. Excelling in certain aspects of health does not equate to total CV protec…
View article: Rationale and Design of the Daita (Digital Advertisements for Inclusive Trial Accrual) Study
Rationale and Design of the Daita (Digital Advertisements for Inclusive Trial Accrual) Study Open
View article: Association of Internet Use with Knowledge of Clinical Trials: An analysis using the Health Information National Trends Survey (HINTS) Dataset 
Association of Internet Use with Knowledge of Clinical Trials: An analysis using the Health Information National Trends Survey (HINTS) Dataset Open