Erin E. Higgins
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View article: Harnessing genomic prediction in <i>Brassica napus</i> through a nested association mapping population
Harnessing genomic prediction in <i>Brassica napus</i> through a nested association mapping population Open
Genomic prediction (GP) significantly enhances genetic gain by improving selection efficiency and shortening crop breeding cycles. Using a nested association mapping population, a set of diverse scenarios were assessed to evaluate GP for i…
View article: A new subgenome of the <i>Camelina</i> genus reveals genome dominance is controlled by chromosomal proximity
A new subgenome of the <i>Camelina</i> genus reveals genome dominance is controlled by chromosomal proximity Open
Summary Camelina sativa is an oilseed of the Brassicaceae , whose close relatives vary in ploidy number, providing a novel platform for studying plant genome evolution. The availability of diploid, tetraploid and hexaploid species of Camel…
View article: Harnessing genome prediction in<i>Brassica napus</i>through a nested association mapping population
Harnessing genome prediction in<i>Brassica napus</i>through a nested association mapping population Open
Genome prediction (GP) significantly enhances genetic gain by improving selection efficiency and shortening crop breeding cycles. Using a nested association mapping (NAM) population a set of diverse scenarios were assessed to evaluate GP f…
View article: A systems genomics and genetics approach to identify the genetic regulatory network for lignin content in Brassica napus seeds
A systems genomics and genetics approach to identify the genetic regulatory network for lignin content in Brassica napus seeds Open
Seed quality traits of oilseed rape, Brassica napus ( B. napus ), exhibit quantitative inheritance determined by its genetic makeup and the environment via the mediation of a complex genetic architecture of hundreds to thousands of genes. …
View article: Mapping QTL for vernalization requirement identified adaptive divergence of the candidate gene <i>Flowering Locus C</i> in polyploid <i>Camelina sativa</i>
Mapping QTL for vernalization requirement identified adaptive divergence of the candidate gene <i>Flowering Locus C</i> in polyploid <i>Camelina sativa</i> Open
Vernalization requirement is an integral component of flowering in winter‐type plants. The availability of winter ecotypes among Camelina species facilitated the mapping of quantitative trait loci (QTL) for vernalization requirement in Cam…
View article: Mapping QTL for vernalization requirement identified adaptive divergence of the candidate gene<i>Flowering Locus C</i>in polyploid<i>Camelina sativa</i>
Mapping QTL for vernalization requirement identified adaptive divergence of the candidate gene<i>Flowering Locus C</i>in polyploid<i>Camelina sativa</i> Open
Vernalization requirement is an integral component of flowering in winter-type plants. The availability of winter ecotypes among Camelina species facilitated the mapping of QTL for vernalization requirement in C. sativa . An inter- and int…
View article: Sequencing of <i>Camelina neglecta</i>, a diploid progenitor of the hexaploid oilseed <i>Camelina sativa</i>
Sequencing of <i>Camelina neglecta</i>, a diploid progenitor of the hexaploid oilseed <i>Camelina sativa</i> Open
Summary Camelina neglecta is a diploid species from the genus Camelina , which includes the versatile oilseed Camelina sativa . These species are closely related to Arabidopsis thaliana and the economically important Brassica crop species,…
View article: Small-molecule ketone esters treat brain network abnormalities in an Alzheimer’s disease mouse model
Small-molecule ketone esters treat brain network abnormalities in an Alzheimer’s disease mouse model Open
Summary Altered brain network activity and the resulting hypersynchrony are important for the pathogenesis of cognitive decline in Alzheimer’s disease (AD) mouse models. Treatments that reduce epileptiform discharges (EDs) or network hyper…
View article: Characterization and Mapping of retr04, retr05 and retr06 Broad-Spectrum Resistances to Turnip Mosaic Virus in Brassica juncea, and the Development of Robust Methods for Utilizing Recalcitrant Genotyping Data
Characterization and Mapping of retr04, retr05 and retr06 Broad-Spectrum Resistances to Turnip Mosaic Virus in Brassica juncea, and the Development of Robust Methods for Utilizing Recalcitrant Genotyping Data Open
Turnip mosaic virus (TuMV) induces disease in susceptible hosts, notably impacting cultivation of important crop species of the Brassica genus. Few effective plant viral disease management strategies exist with the majority of current appr…
View article: Exploiting High-Throughput Indoor Phenotyping to Characterize the Founders of a Structured B. napus Breeding Population
Exploiting High-Throughput Indoor Phenotyping to Characterize the Founders of a Structured B. napus Breeding Population Open
Phenotyping is considered a significant bottleneck impeding fast and efficient crop improvement. Similar to many crops, Brassica napus , an internationally important oilseed crop, suffers from low genetic diversity, and will require exploi…
View article: Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI
Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI Open
Quorum sensing is a bacterial signaling system that involves the synthesis and detection of small signal molecules called autoinducers. A main class of autoinducers in Gram-negative bacteria are acylated homoserine lactones, produced by th…
View article: Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI
Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI Open
Quorum sensing is a bacterial signaling system that involves the synthesis and subsequent detection of small signal molecules called autoinducers. The main autoinducer in gram-negative bacteria are acylated homoserine lactones (AHLs), prod…
View article: Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI
Design, Synthesis, and Evaluation of Transition-State Analogs as Inhibitors of the Bacterial Quorum Sensing Autoinducer Synthase CepI Open
Quorum sensing is a bacterial signaling system that involves the synthesis and detection of small signal molecules called autoinducers. A main class of autoinducers in Gram-negative bacteria are acylated homoserine lactones, produced by th…
View article: A major quantitative trait locus on chromosome A9, <i>BnaPh1</i>, controls homoeologous recombination in <i>Brassica napus</i>
A major quantitative trait locus on chromosome A9, <i>BnaPh1</i>, controls homoeologous recombination in <i>Brassica napus</i> Open
Summary Ensuring faithful homologous recombination in allopolyploids is essential to maintain optimal fertility of the species. Variation in the ability to control aberrant pairing between homoeologous chromosomes in Brassica napus has bee…
View article: A high-contiguity Brassica nigra genome localizes active centromeres and defines the ancestral Brassica genome
A high-contiguity Brassica nigra genome localizes active centromeres and defines the ancestral Brassica genome Open
It is only recently, with the advent of long-read sequencing technologies, that we are beginning to uncover previously uncharted regions of complex and inherently recursive plant genomes. To comprehensively study and exploit the genome of …
View article: Narrow genetic base shapes population structure and linkage disequilibrium in an industrial oilseed crop, Brassica carinata A. Braun
Narrow genetic base shapes population structure and linkage disequilibrium in an industrial oilseed crop, Brassica carinata A. Braun Open
Ethiopian mustard ( Brassica carinata A. Braun) is an emerging sustainable source of vegetable oil, in particular for the biofuel industry. The present study exploited genome assemblies of the Brassica diploids, Brassica nigra and Brassica…
View article: High contiguity long read assembly of<i>Brassica nigra</i>allows localization of active centromeres and provides insights into the ancestral<i>Brassica</i>genome
High contiguity long read assembly of<i>Brassica nigra</i>allows localization of active centromeres and provides insights into the ancestral<i>Brassica</i>genome Open
High-quality nanopore genome assemblies were generated for two Brassica nigra genotypes (Ni100 and CN115125); a member of the agronomically important Brassica species. The N50 contig length for the two assemblies were 17.1 Mb (58 contigs) …
View article: Acknowledgments
Acknowledgments Open
Detecting<i>de Novo</i>Homoeologous Recombination Events in Cultivated<i>Brassica napus</i>Using a Genome-Wide SNP Array Open
View article: A high-density SNP genotyping array for Brassica napus and its ancestral diploid species based on optimised selection of single-locus markers in the allotetraploid genome
A high-density SNP genotyping array for Brassica napus and its ancestral diploid species based on optimised selection of single-locus markers in the allotetraploid genome Open
View article: An Investigation of the Impact of Multiple Exposures to New Vocabulary Words have on Students with Language Processing Disorders
An Investigation of the Impact of Multiple Exposures to New Vocabulary Words have on Students with Language Processing Disorders Open
The purpose of this research aimed to investigate how fifth-grade students diagnosed with processing disorders best-learned new vocabulary and the role motivation played in success. The district, school, and students were given pseudonyms …
View article: Seedling development traits in Brassica napus examined by gene expression analysis and association mapping
Seedling development traits in Brassica napus examined by gene expression analysis and association mapping Open
A total of 99.4% of the adjacent SNPs on the A genome and 93.0% of the adjacent SNPs on the C genome had a distance smaller than the average range of linkage disequilibrium. Therefore, this genome-wide association study is expected to resu…
View article: Single-nucleotide polymorphism identification and genotyping in Camelina sativa
Single-nucleotide polymorphism identification and genotyping in Camelina sativa Open
Camelina sativa, a largely relict crop, has recently returned to interest due to its potential as an industrial oilseed. Molecular markers are key tools that will allow C. sativa to benefit from modern breeding approaches. Tw…