Erin K. Wagner
YOU?
Author Swipe
View article: Acknowledgements
Acknowledgements Open
For a lone medievalist at a small teaching college, the support of colleagues, friends, and family is critical in the development of any research project.
View article: Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche Open
Age at menarche is a marker of timing of puberty in females. It varies widely between individuals, is a heritable trait and is associated with risks for obesity, type 2 diabetes, cardiovascular disease, breast cancer and all-cause mortalit…
View article: Phase I Study of Ramucirumab Plus Merestinib in Previously Treated Metastatic Colorectal Cancer: Safety, Preliminary Efficacy, and Pharmacokinetic Findings
Phase I Study of Ramucirumab Plus Merestinib in Previously Treated Metastatic Colorectal Cancer: Safety, Preliminary Efficacy, and Pharmacokinetic Findings Open
Trial Information Click here to access other published clinical trials. Lessons Learned The combination of the antivascular endothelial growth factor receptor 2 monoclonal antibody, ramucirumab, and the type II MET kinase inhibitor, merest…
View article: Extending TCGA queries to automatically identify analogous genomic data from dbGaP
Extending TCGA queries to automatically identify analogous genomic data from dbGaP Open
Data sharing is critical to advance genomic research by reducing the demand to collect new data by reusing and combining existing data and by promoting reproducible research. The Cancer Genome Atlas (TCGA) is a popular resource for individ…
View article: Long intergenic non-coding RNA expression signature in human breast cancer
Long intergenic non-coding RNA expression signature in human breast cancer Open
View article: Protective coding variants in<i>CFH</i>and<i>PELI3</i>and a variant near<i>CTRB1</i>are associated with age-related macular degeneration<sup>†</sup>
Protective coding variants in<i>CFH</i>and<i>PELI3</i>and a variant near<i>CTRB1</i>are associated with age-related macular degeneration<sup>†</sup> Open
Although numerous common age-related macular degeneration (AMD) alleles have been discovered using genome-wide association studies, substantial disease heritability remains unexplained. We sought to identify additional common and rare vari…
View article: NCBI-Hackathons/TCGA_dbGaP: TCGA_dbGaP_v1.0
NCBI-Hackathons/TCGA_dbGaP: TCGA_dbGaP_v1.0 Open
Find dbGaP studies from TCGA and vice versa
View article: Novel associations with age-related macular degeneration: a common variant near CTRB1 and a protective rare variant in PELI3
Novel associations with age-related macular degeneration: a common variant near CTRB1 and a protective rare variant in PELI3 Open
View article: Age-Related Macular Degeneration Genetic Variation in Armenian Population
Age-Related Macular Degeneration Genetic Variation in Armenian Population Open
View article: Choroidal and Outer Retinal OCT Features Preceding Development of Geographic Atrophy
Choroidal and Outer Retinal OCT Features Preceding Development of Geographic Atrophy Open
View article: Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer
Tissue-specific Co-expression of Long Non-coding and Coding RNAs Associated with Breast Cancer Open
View article: Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden and lower antigenic levels in familial AMD
Mapping rare, deleterious mutations in Factor H: Association with early onset, drusen burden and lower antigenic levels in familial AMD Open
The genetic architecture of age-related macular degeneration (AMD) involves numerous genetic variants, both common and rare, in the coding region of complement factor H ( CFH ). While these variants explain high disease burden in some fami…
View article: Protective coding variants in<i>CFH</i>and<i>PELI3</i>and a variant near<i>CTRB1</i>are associated with age-related macular degeneration
Protective coding variants in<i>CFH</i>and<i>PELI3</i>and a variant near<i>CTRB1</i>are associated with age-related macular degeneration Open
Although >20 common frequency age-related macular degeneration (AMD) alleles have been discovered with genome-wide association studies, substantial disease heritability remains unexplained. In this study we sought to identify additional va…
View article: Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration
Rare Variants in the Functional Domains of Complement Factor H Are Associated With Age-Related Macular Degeneration Open
In this large A-AMD cohort, rare variants in the CFH gene were enriched and tended to be located in functional sites or led to low serum levels. These data, combined with those indicating a similar, but even more striking, increase in rare…