Erin LaMontagne
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View article: Author Correction: Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
Author Correction: Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content Open
View article: Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation
Conductive electrospun polymer improves stem cell-derived cardiomyocyte function and maturation Open
View article: Profiling of repetitive RNA sequences in the blood plasma of patients with cancer
Profiling of repetitive RNA sequences in the blood plasma of patients with cancer Open
Liquid biopsies provide a means for the profiling of cell-free RNAs secreted by cells throughout the body. Although well-annotated coding and non-coding transcripts in blood are readily detectable and can serve as biomarkers of disease, th…
View article: Recent advancements and future requirements in vascularization of cortical organoids
Recent advancements and future requirements in vascularization of cortical organoids Open
The fields of tissue engineering and disease modeling have become increasingly cognizant of the need to create complex and mature structures in vitro to adequately mimic the in vivo niche. Specifically for neural applications, human brain …
View article: Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes
Mutant KRAS regulates transposable element RNA and innate immunity via KRAB zinc-finger genes Open
RAS genes are the most frequently mutated oncogenes in cancer, yet the effects of oncogenic RAS signaling on the noncoding transcriptome remain unclear. We analyzed the transcriptomes of human airway and bronchial epithelial cells transfor…
View article: Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content Open
Transcription Factor 4 ( TCF4) has been associated with autism, schizophrenia, and other neuropsychiatric disorders. However, how pathological TCF4 mutations affect the human neural tissue is poorly understood. Here, we derive neural proge…
View article: Epigenomic reprogramming of repetitive noncoding RNAs and IFN-stimulated genes by mutant KRAS
Epigenomic reprogramming of repetitive noncoding RNAs and IFN-stimulated genes by mutant KRAS Open
RAS genes are the most frequently mutated oncogenes in cancer. However, the effects of oncogenic RAS signaling on the noncoding transcriptome are unclear. We analyzed the transcriptomes of human airway epithelial cells transformed with mut…
View article: Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes
Structurally Conserved Primate LncRNAs Are Transiently Expressed during Human Cortical Differentiation and Influence Cell-Type-Specific Genes Open
The cerebral cortex has expanded in size and complexity in primates, yet the molecular innovations that enabled primate-specific brain attributes remain obscure. We generated cerebral cortex organoids from human, chimpanzee, orangutan, and…
View article: Structurally Conserved Primate lncRNAs Are Transiently Expressed During Human Cortical Differentiation and Influence Cell Type Specific Genes
Structurally Conserved Primate lncRNAs Are Transiently Expressed During Human Cortical Differentiation and Influence Cell Type Specific Genes Open
View article: Structurally conserved primate lncRNAs are transiently expressed during human cortical differentiation and influence cell type specific genes
Structurally conserved primate lncRNAs are transiently expressed during human cortical differentiation and influence cell type specific genes Open
SUMMARY The cerebral cortex has expanded in size and complexity in primates, yet the underlying molecular mechanisms are obscure. We generated cortical organoids from human, chimpanzee, orangutan, and rhesus pluripotent stem cells and sequ…
View article: Off-Label Promotion, the First Amendment, and Practically Addressing Antibiotic Resistance
Off-Label Promotion, the First Amendment, and Practically Addressing Antibiotic Resistance Open