Explanipedia

DACIT: Device for Axon - Cancer Cell Interaction Testing in 2D & 3D Open

Ines Velazquez Quesada, Vahid Alizadeh, Kara Allison, Elizaveta Belova, Svetllana Kallogjerovic , et al. · 2025

Device for Axon - Cancer cell Interaction Testing in 2D & 3D: DACIT Open

Inés Velázquez‐Quesada, Vahid Alizadeh, Kara Allison, Elizaveta Belova, Svetllana Kallogjerovic , et al. · 2024

Summary There is increasing interest in studying the role of peripheral innervation in tumor growth and metastasis. However, in vitro studies of interactions between cancer cells and axonal projections are technically challenging. To addre…

Invadopodia enable cooperative invasion and metastasis of breast cancer cells Open

Louisiane Perrin, Elizaveta Belova, Battuya Bayarmagnai, Erkan Tüzel, Bojana Gligorijevic · 2022

Invasive and non-invasive cancer cells can invade together during cooperative invasion. However, the events leading to it, role of the epithelial-mesenchymal transition and the consequences this may have on metastasis are unknown. In this …

Measurement of the persistence length of cytoskeletal filaments using curvature distributions Open

Pattipong Wisanpitayakorn, Keith J. Mickolajczyk, William O. Hancock, Luis Vidali, Erkan Tüzel · 2022

Myosin XI drives polarized growth by vesicle focusing and local enrichment of F-actin in Physcomitrium patens Open

Giulia Galotto, Pattipong Wisanpitayakorn, Jeffrey P. Bibeau, Yen-Chun Liu, Fabienne Furt , et al. · 2021

In tip-growing plant cells, growth results from myosin XI and F-actin-mediated deposition of cell wall polysaccharides contained in secretory vesicles. Previous evidence showed that myosin XI anticipates F-actin accumulation at the cell’s …

Invadopodia enable cooperative invasion and metastasis of breast cancer cells Open

Louisiane Perrin, Battuya Bayarmagnai, Erkan Tüzel, Bojana Gligorijevic · 2021

Multiple clones of cancer cells can seed metastases via collective invasion and dissemination. While it is known that cancer clones can cooperate during invasion, the events leading to it and the effects it may have on metastasis are not k…

Quantitative cell biology of tip growth in moss Open

Jeffrey P. Bibeau, Giulia Galotto, Min Wu, Erkan Tüzel, Luis Vidali · 2021

Invadopodia enable cooperative invasion and metastasis of breast cancer cells Open

Louisiane Perrin, Елена Белова, Battuya Bayarmagnai, Erkan Tüzel, Bojana Gligorijevic · 2021

Invasive and non-invasive cancer cells can invade together during the cooperative invasion. However, the events leading to it, role of EMT and the consequences this may have on metastasis are unknown. In this study, we demonstrate that the…

“Myosin XI drives polarized growth by vesicle clustering and local enrichment of F-actin inPhyscomitrium (Physcomitrella) patens” Open

Giulia Galotto, Pattipong Wisanpitayakorn, Jeffrey P. Bibeau, Yen‐Chun Liu, Parker J. Simpson , et al. · 2020

In tip-growing plant cells, growth results from myosin XI and F-actin mediated deposition of cell wall polysaccharides contained in secretory vesicles. Previous evidence showed that myosin XI anticipates F-actin accumulation at the cell’s …

Kinesin-2 from C. reinhardtii Is an Atypically Fast and Auto-inhibited Motor that Is Activated by Heterotrimerization for Intraflagellar Transport Open

Punam Sonar, Wiphu Youyen, Augustine Cleetus, Pattipong Wisanpitayakorn, Sayed Iman Mousavi , et al. · 2020

Re-track: Software to analyze the retraction and protrusion velocities of neurites, filopodia and other structures Open

Sayed Iman Mousavi, Katherine M. Pearce, Suzanne Scarlata, Erkan Tüzel · 2020

We have developed new software, Re-track, that will quantify the rates of retraction and protrusion of structures emanating from the central core of a cell, such as neurites or filopodia. Re-Track, uses time-lapse images of cells in TIFF f…

Three-Dimensional Model to Understand the Cooperative Transport of Pairs of Kinesin-2 Motors Open

Wiphu Youyen, Punam Sonar, Pattipong Wisanpitayakorn, Qingzhou Feng, Keith J. Mickolajczyk , et al. · 2020

In vivo interactions between myosin XI, vesicles and filamentous actin are fast and transient in Physcomitrella patens Open

Jeffrey P. Bibeau, Fabienne Furt, Sayed Iman Mousavi, James L. Kingsley, Max F. Levine , et al. · 2020

The actin cytoskeleton and active membrane trafficking machinery are essential for polarized cell growth. To understand the interactions between myosin XI, vesicles and actin filaments in vivo, we performed fluorescence recovery after phot…

Microtubule binding kinetics of membrane-bound kinesin-1 predicts high motor copy numbers on intracellular cargo Open

Rui Jiang, Steven Vandal, Soo-Hyun Park, Sheereen Majd, Erkan Tüzel , et al. · 2019

Bidirectional vesicle transport along microtubules is necessary for cell viability and function, particularly in neurons. When multiple motors are attached to a vesicle, the distance a vesicle travels before dissociating is determined by t…

Kinesin-2 from C. reinhardtii is an atypically fast and auto-inhibited motor that is activated by heterotrimerization for intraflagellar transport Open

Punam Sonar, Wiphu Youyen, Augustine Cleetus, Pattipong Wisanpitayakorn, Iman S. Mousavi , et al. · 2019

Summary The construction and function of virtually all cilia require the universally conserved process of Intraflagellar Transport (IFT) [1, 2]. During the atypically fast IFT in the green alga C. reinhardtii , up to ten kinesin-2 motors ‘…

Invadopodia-mediated ECM degradation is enhanced in the G1 phase of the cell cycle Open

Battuya Bayarmagnai, Louisiane Perrin, Kamyar Esmaeili Pourfarhangi, Xavier Graña, Erkan Tüzel , et al. · 2019

The process of tumor cell invasion and metastasis includes assembly of invadopodia, protrusions capable of degrading the extracellular matrix (ECM). The effect of cell cycle progression on invadopodia has not been elucidated. In this study…

Microtubule Binding Kinetics of Membrane-bound Kinesin Predicts High Motor Copy Numbers on Intracellular Cargo Open

Rui Jiang, Steven Vandal, Soo-Hyun Park, Sheereen Majd, Erkan Tüzel , et al. · 2019

Bidirectional vesicle transport along microtubules is necessary for cell viability and function, particularly in neurons. When multiple motors are attached to a vesicle, the distance a vesicle travels before dissociating is determined by t…

In vivoInteractions between Myosin XI, Vesicles, and Filamentous Actin Are Fast and Transient Open

Jeffrey P. Bibeau, Fabienne Furt, Sayed Iman Mousavi, James L. Kingsley, Max F. Levine , et al. · 2019

The apical actin cytoskeleton and active membrane trafficking machinery are essential in driving polarized cell growth. To better understand the interactions between myosin XI, vesicles, and actin filament in vivo , we performed Fluorescen…

Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors Open

Göker Arpağ, Stephen R. Norris, Sayed Iman Mousavi, Virupakshi Soppina, Kristen J. Verhey , et al. · 2019

Binding Kinetics between Membrane-Bound Kinesin Motors and Microtubules Open

Rui Jiang, Soo-Hyun Park, Steven Vandal, Erkan Tüzel, Sheereen Majd , et al. · 2019

Three-Dimensional Model of Cooperative Transport of Pairs of Kinesin-1 and −2 Motors Open

Wiphu Youyen, Iman S. Mousavi, Keith J. Mickolajczyk, William O. Hancock, Erkan Tüzel · 2019

Characterization of Cell Boundary and Confocal Effects Improves Quantitative FRAP Analysis Open

James L. Kingsley, Jeffrey P. Bibeau, Sayed Iman Mousavi, Cem Unsal, Zhilu Chen , et al. · 2018

Understanding Boundary Effects and Confocal Optics Enables Quantitative FRAP Analysis in the Confined Geometries of Animal, Plant and Fungal Cells Open

James L. Kingsley, Jeffrey P. Bibeau, Sayed Iman Mousavi, Cem Unsal, Zhilu Chen , et al. · 2018

F-Actin Meditated Focusing of Vesicles at the Cell Tip is Essential for Polarized Growth Open

Jeffrey P. Bibeau, James L. Kingsley, Fabienne Furt, Erkan Tüzel, Luis Vidali · 2018

Microfluidics: Guidance and Self‐Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest (Adv. Sci. 2/2018) Open

Thiruppathiraja Chinnasamy, James L. Kingsley, Fatih İnci, Paul J. Turek, Mitchell P. Rosen , et al. · 2018

A modelâdriven design featuring pillar arrays that efficiently and nonâinvasively isolate highly motile and morphological normal sperm, with normal epigenetic global methylation, is presented by Erkan TÃ¼zel, Utkan Demirci, and coâwo…

Measurement of the Persistence Length of Cytoskeletal Filaments using Curvature Distributions Open

Pattipong Wisanpitayakorn, Keith J. Mickolajczyk, William O. Hancock, Luis Vidali, Erkan Tüzel · 2018

Cytoskeletal filaments such as microtubules and actin filaments play important roles in the mechanical integrity of cells and the ability of cells to respond to their environment. Measuring the mechanical properties of cytoskeletal structu…

Guidance and Self‐Sorting of Active Swimmers: 3D Periodic Arrays Increase Persistence Length of Human Sperm Selecting for the Fittest Open

Thiruppathiraja Chinnasamy, James L. Kingsley, Fatih İnci, Paul J. Turek, Mitchell P. Rosen , et al. · 2017

Male infertility is a reproductive disease, and existing clinical solutions for this condition often involve long and cumbersome sperm sorting methods, including preprocessing and centrifugation‐based steps. These methods also fall short w…

Enhanced flagellar transport in asymmetric periodic arrays Open

James L. Kingsley, Utkan Demirci, Erkan Tüzel · 2017

Active swimmers are ubiquitous in nature, found in many diverse biological systems ranging from bacteria to vertebrate fish. Of particular importance are sperm cells which are swimmers that are crucial for the survival of many species incl…

F-Actin Mediated Focusing of Vesicles at the Cell Tip Is Essential for Polarized Growth Open

Jeffrey P. Bibeau, James L. Kingsley, Fabienne Furt, Erkan Tüzel, Luis Vidali · 2017

F-actin has been shown to be essential for tip growth in an array of plant models, including Physcomitrella patens One hypothesis is that diffusion can transport secretory vesicles, while actin plays a regulatory role during secreti…

Monitoring Neutropenia for Cancer Patients at the Point of Care Open

Hakan Inan, James L. Kingsley, Mehmet Ozgün Ozen, H. Cumhur Tekin, Christian R. Hoerner , et al. · 2017

Neutrophils have a critical role in regulating the immune system. The immune system is compromised during chemotherapy, increasing infection risks and imposing a need for regular monitoring of neutrophil counts. Although commercial hematol…

Erkan Tüzel YOU? Author Swipe