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View article: Oxidative stress and metabolic parameters in hypertensive patients with/without diabetes mellitus in cardiovascular risk evaluation
Oxidative stress and metabolic parameters in hypertensive patients with/without diabetes mellitus in cardiovascular risk evaluation Open
Introduction: Hypertension and diabetes mellitus affect a large number of patients and can significantly influence their life expectancy. Changes in metabolic and oxidative stress parameters are common in these pathologies, contributing to…
View article: Determination of the sun protection factor of sunscreens
Determination of the sun protection factor of sunscreens Open
Proper sun protection plays a key role in protecting against the harmful effects of UV radiation from the sun. Using sunscreen products protects the skin from sunburn, prevents it from ageing and reduces the risk of skin cancer. The aim of…
View article: Profiling the Concentration of Reduced and Oxidized Glutathione in Rat Brain Using HPLC/DAD Chromatographic System
Profiling the Concentration of Reduced and Oxidized Glutathione in Rat Brain Using HPLC/DAD Chromatographic System Open
This study aimed to develop a HPLC/DAD method in order to determine and quantify the reduced glutathione (GSH) and oxidized glutathione (GSSG) levels in rat brain. Due to the presence of the thiol group (-SH), GSH can interact with the Ell…
View article: A Simple HPLC/DAD Method Validation for the Quantification of Malondialdehyde in Rodent’s Brain
A Simple HPLC/DAD Method Validation for the Quantification of Malondialdehyde in Rodent’s Brain Open
In the present study, a HPLC/DAD method was set up to allow for the determination and quantification of malondialdehyde (MDA) in the brain of rodents (rats). Chromatographic separation was achieved on Supelcosil LC-18 (3 μm) SUPELCO Column…
View article: Oxidative stress and peripartum outcomes (Review)
Oxidative stress and peripartum outcomes (Review) Open
Pregnancy, labor and childbirth are accompanied by excessive oxidative aggression. The excessive formation of free radicals [reactive oxygen species (ROS), reactive nitrogen species (RNS), chlorine reactive species (CRS)] causes cellular o…
View article: Study of pharmaceutical competences among the Romanian population, based on an online survey
Study of pharmaceutical competences among the Romanian population, based on an online survey Open
From the year 1990s the pharmaceutical competences https://www.thesaurus.com/browse/assignment based on drug supply has been completed with the patient consultation and communication. This fact has greatly expanded the work of the pharmaci…
View article: Characterization of the Site‐Specific Acid‐Base Equilibria of 3‐Nitrotyrosine
Characterization of the Site‐Specific Acid‐Base Equilibria of 3‐Nitrotyrosine Open
The complete macro‐ and microequilibrium analyses of 3‐nitrotyrosine, a biomarker of oxidative stress damage, are presented for the first time. The protonation macroconstants were determined by 1 H‐NMR‐pH titration, while microconstants we…
View article: Three-Year Follow-up of Smoking Prevalence, Knowledge, Attitudes and Beliefs Among Pharmacy Students at UMPhST, Targu Mures
Three-Year Follow-up of Smoking Prevalence, Knowledge, Attitudes and Beliefs Among Pharmacy Students at UMPhST, Targu Mures Open
Objectives of the study were to investigate the smoking prevalence, knowledge, attitudes and beliefs among Romanian pharmacy students. Surveys were conducted among pharmacy students during 2014�2016. A locally-adapted version of the Global…
View article: Aluminium contamination of several types of tea
Aluminium contamination of several types of tea Open
Introduction: Camellia sinensis, a widely used plant, optimally grows in a low pH soil that in most cases contains high amounts of aluminum. Objectives: The aluminum content of the tea obtained from Camellia sinensis and other plants was c…
View article: Chemical properties of several red wines available on Romanian and also on the international market
Chemical properties of several red wines available on Romanian and also on the international market Open
The aim of this study was to perform a phytochemical analysis of 28 red wines available on Romanian and also on the
\ninternational market. The identification of 14 polyphenols and their quantitative analysis were performed by HPLC/ESI-MS
…
View article: The Risk of Using Poppy Seed Tea Made from Several Varieties Available on the Romanian Market
The Risk of Using Poppy Seed Tea Made from Several Varieties Available on the Romanian Market Open
Objective: the number of alkaloids like morphine and codeine found in poppy seeds used in food industry are monitored by a directive given by European Food Safety Authority. Based on this regulation the aim of the study was to determine th…
View article: Could Codeine Containing OTC Analgesics Sold in Romania be Used as Recreational Drugs?
Could Codeine Containing OTC Analgesics Sold in Romania be Used as Recreational Drugs? Open
Objective : Analgesic medicines containing combinations of nonsteroidal anti-inflammatory drugs and codeine are available without prescription. Codeine, in these combinations can not be used recreationally due to the high toxicity profile …
View article: In Vitro Interactions of Diclofenac with Several Types of Food
In Vitro Interactions of Diclofenac with Several Types of Food Open
Objective : The aim of this study was to evaluate how the membrane transport of diclofenac on presence of different types of food is modified. Methods : The interaction of diclofenac, as a pure substance and solid dispersions of the active…
View article: Malondialdehyde levels can be measured in serum and saliva by using a fast HPLC method with visible detection / Determinarea printr-o metodă HPLC-VIS rapidă a concentraţiilor serice şi salivare ale malondialdehidei
Malondialdehyde levels can be measured in serum and saliva by using a fast HPLC method with visible detection / Determinarea printr-o metodă HPLC-VIS rapidă a concentraţiilor serice şi salivare ale malondialdehidei Open
Oxidative stress appears when the amount of free radicals that are formed in a living organism exceed its spin-trapping ability. One of the most dangerous free radicals that are formed in the human body is the hydroxyl radical. It can alte…
View article: Study On Metabolic And Mineral Balance, Oxidative Stress And Cardiovascular Risk Factors In Type 2 Diabetic Patients On Different Therapy
Study On Metabolic And Mineral Balance, Oxidative Stress And Cardiovascular Risk Factors In Type 2 Diabetic Patients On Different Therapy Open
Intense oxidative stress, increased glycated hemoglobin and mineral imbalance represent risk factors for complications in diabetic patients. Cardiovascular complications are most common in these patients, including nephropathy. This study …
View article: Is the Oxidative Stress Really a Disease?
Is the Oxidative Stress Really a Disease? Open
Oxidative stress is an imbalance between free radicals or other reactive species and the antioxidant activity of the organism. Oxidative stress can induce several illnesses such as cardiovascular disease, neurodegenerative disorders, diabe…
View article: Presence of Nitrate and Nitrite in Well Water in Mureș County
Presence of Nitrate and Nitrite in Well Water in Mureș County Open
Objective: One of the most important sources of nitrite and nitrate anions, besides vegetables and meat products, is the drinking water. Presence of nitrite and nitrate in the water in higher concentrations than those set by EFSA (0.5 mg/l…