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View article: Quantification of muscle glycogen distribution in Pompe disease using 7 Tesla <sup>13</sup>C NMR spectroscopy
Quantification of muscle glycogen distribution in Pompe disease using 7 Tesla <sup>13</sup>C NMR spectroscopy Open
Background Late-onset Pompe disease has a characteristic pattern of fat replacement and wasting of especially axial and hamstring muscles. This characteristic pattern of muscle degeneration is still to be explained but could relate to diff…
View article: The Mode of Operation of High‐Impedance Coils and Shielded Coaxial Cable Coils: A Comparative Study
The Mode of Operation of High‐Impedance Coils and Shielded Coaxial Cable Coils: A Comparative Study Open
High‐impedance coils (HICs) and shielded coaxial cable coils (SCCs) are of the same physical structure but with different matching networks and different input impedances (which depend on the mode of operation). This article explores the w…
View article: High-Field Optical Cesium Magnetometer for Magnetic Resonance Imaging
High-Field Optical Cesium Magnetometer for Magnetic Resonance Imaging Open
We present a novel high-field optical quantum magnetometer based on saturated absorption spectroscopy on the extreme angular-momentum states of the cesium D2 line. With key features including continuous readout, high sampling rate, and sen…
View article: End-to-end volumetric segmentation of white matter hyperintensities using deep learning
End-to-end volumetric segmentation of white matter hyperintensities using deep learning Open
DL methods generally surpassed conventional approaches in our study. While all DL methods performed comparably, incorporating attention mechanisms could prove advantageous in future applications with a wider availability of training data. …
View article: The effect of dairy products on liver fat and metabolic risk markers in males with abdominal obesity – a four-arm randomized controlled trial
The effect of dairy products on liver fat and metabolic risk markers in males with abdominal obesity – a four-arm randomized controlled trial Open
gov (# NCT04755530).
View article: High-Field Optical Cesium Magnetometer for Magnetic Resonance Imaging
High-Field Optical Cesium Magnetometer for Magnetic Resonance Imaging Open
We present a novel high-field optical quantum magnetometer based on saturated absorption spectroscopy on the extreme angular-momentum states of the cesium D2 line. With key features including continuous readout, high sampling rate, and sen…
View article: X-linked creatine transporter (SLC6A8) deficiency in females: Difficult to recognize, but a potentially treatable disease
X-linked creatine transporter (SLC6A8) deficiency in females: Difficult to recognize, but a potentially treatable disease Open
View article: Precision Measurement of the Excited State Landé g-factor and Diamagnetic Shift of the Cesium <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" display="inline"><mml:mrow><mml:msub><mml:mrow><mml:mi mathvariant="normal">D</mml:mi></mml:mrow><mml:mrow><mml:mn>2</mml:mn></mml:mrow></mml:msub></mml:mrow></mml:math> Line
Precision Measurement of the Excited State Landé g-factor and Diamagnetic Shift of the Cesium Line Open
Transitions between the extreme angular-momentum states of alkali D lines hold the potential for enabling accurate high-field optical magnetometry because of their very simple magnetic field dependence described only by a linear and a quad…
View article: Negotiating Otherness? Mission Discourse of Difference among the Swiss and German Schooling Projects in 19th Century Japan
Negotiating Otherness? Mission Discourse of Difference among the Swiss and German Schooling Projects in 19th Century Japan Open
This article explores the personal encounters between the Swiss–German missionaries and their Japanese students through their school projects in the late nineteenth century, as a fresh approach to disclose an entirely new analytical angle …
View article: Precision Measurement of the Excited State Landé g-factor and Diamagnetic Shift of the Cesium D$_{2}$ Line
Precision Measurement of the Excited State Landé g-factor and Diamagnetic Shift of the Cesium D$_{2}$ Line Open
We have performed saturated absorption spectroscopy on the cesium D$_{2}$ line in 3 T and 7 T magnetic fields. By means of sideband spectroscopy on the extreme angular momentum states we have measured the linear magnetic frequency shift of…
View article: Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications
Neurovascular Coupling in Type 2 Diabetes With Cognitive Decline. A Narrative Review of Neuroimaging Findings and Their Pathophysiological Implications Open
Type 2 diabetes causes substantial long-term damage in several organs including the brain. Cognitive decline is receiving increased attention as diabetes has been established as an independent risk factor along with the identification of s…
View article: Short periods of bipolar anodal TDCS induce no instantaneous dose-dependent increase in cerebral blood flow in the targeted human motor cortex
Short periods of bipolar anodal TDCS induce no instantaneous dose-dependent increase in cerebral blood flow in the targeted human motor cortex Open
View article: Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the AMEND Trial Protocol
Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the AMEND Trial Protocol Open
Background Antipsychotic drugs are primarily efficacious in treating positive symptoms by blocking the dopamine D2 receptor, but they fail to substantially improve negative symptoms and cognitive deficits. The limited efficacy may be attri…
View article: Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field
Improving brain B0 shimming using an easy and accessible multi-coil shim array at ultra-high field Open
View article: Short Periods of Bipolar Anodal TDCS Induce No Instantaneous Dose-Dependent Increase in Cerebral Blood Flow in the Targeted Human Motor Cortex
Short Periods of Bipolar Anodal TDCS Induce No Instantaneous Dose-Dependent Increase in Cerebral Blood Flow in the Targeted Human Motor Cortex Open
Background Anodal transcranial direct current stimulation (aTDCS) of primary motor hand area (M1-HAND) can enhance corticomotor excitability. Yet, it is still unknown which current intensity produces the strongest effect on regional neural…
View article: Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease
Locus Coeruleus Shows a Spatial Pattern of Structural Disintegration in Parkinson's Disease Open
Background Parkinson's disease (PD) causes a loss of neuromelanin‐positive, noradrenergic neurons in the locus coeruleus (LC), which has been implicated in nonmotor dysfunction. Objectives We used “neuromelanin sensitive” magnetic resonanc…
View article: Short periods of bipolar anodal TDCS induce no instantaneous dose-dependent increase in cerebral blood flow in the targeted human motor cortex
Short periods of bipolar anodal TDCS induce no instantaneous dose-dependent increase in cerebral blood flow in the targeted human motor cortex Open
Background Anodal transcranial direct current stimulation (aTDCS) of primary motor hand area (M1-HAND) can enhance corticomotor excitability. Yet, it is still unknown which current intensity produces the strongest effect on regional neural…
View article: The locus coeruleus shows a spatial pattern of structural disintegration in Parkinson’s disease
The locus coeruleus shows a spatial pattern of structural disintegration in Parkinson’s disease Open
Background Parkinson’s disease (PD) leads to a loss of neuromelanin positive, noradrenergic neurons in the locus coeruleus (LC) which has been implicated in non-motor dysfunction. “Neuromelanin sensitive” magnetic resonance imaging (MRI) h…
View article: Do glia provide the link between low‐grade systemic inflammation and normal cognitive ageing? A <sup>1</sup>H magnetic resonance spectroscopy study at 7 tesla
Do glia provide the link between low‐grade systemic inflammation and normal cognitive ageing? A <sup>1</sup>H magnetic resonance spectroscopy study at 7 tesla Open
Low‐grade systemic inflammation contributes to ageing‐related cognitive decline, possibly by triggering a neuroinflammatory response through glial activation. Using proton magnetic resonance spectroscopy ( 1 H‐MRS) at 7T in normal human in…
View article: Prospective frequency and motion correction for edited 1H magnetic resonance spectroscopy
Prospective frequency and motion correction for edited 1H magnetic resonance spectroscopy Open
The major inhibitory neurotransmitter gamma-aminobutyric acid (GABA) and the dominant antioxidant glutathione (GSH) both play a crucial role in brain functioning and are involved in several neurodegenerative and psychiatric diseases. Magne…
View article: Feasibility of Glutamate and GABA Detection in Pons and Thalamus at 3T and 7T by Proton Magnetic Resonance Spectroscopy
Feasibility of Glutamate and GABA Detection in Pons and Thalamus at 3T and 7T by Proton Magnetic Resonance Spectroscopy Open
Glutamate detection in pons and thalamus using proton magnetic resonance spectroscopy (1H-MRS) after an intervention is of interest for studying various brain disorders. However, 1H-MRS in these brain regions is chall…
View article: Regional Myo-Inositol, Creatine, and Choline Levels Are Higher at Older Age and Scale Negatively with Visuospatial Working Memory: A Cross-Sectional Proton MR Spectroscopy Study at 7 Tesla on Normal Cognitive Ageing
Regional Myo-Inositol, Creatine, and Choline Levels Are Higher at Older Age and Scale Negatively with Visuospatial Working Memory: A Cross-Sectional Proton MR Spectroscopy Study at 7 Tesla on Normal Cognitive Ageing Open
Proton MR spectroscopy ( 1 H-MRS) has been used to assess regional neurochemical brain changes during normal ageing, but results have varied. Exploiting the increased sensitivity at ultra-high field, we performed 1 H-MRS in 60 healthy huma…
View article: MR spectroscopy using static higher order shimming with dynamic linear terms (HOS‐DLT) for improved water suppression, interleaved MRS‐fMRI, and navigator‐based motion correction at 7T
MR spectroscopy using static higher order shimming with dynamic linear terms (HOS‐DLT) for improved water suppression, interleaved MRS‐fMRI, and navigator‐based motion correction at 7T Open
Purpose To interleave global and local higher order shimming for single voxel MRS. Single voxel MR spectroscopy requires optimization of the B 0 field homogeneity in the region of the voxel to obtain a narrow linewidth and provide high dat…
View article: Cerebral oxygen metabolism in adults with sickle cell disease
Cerebral oxygen metabolism in adults with sickle cell disease Open
In sickle cell disease (SCD), oxygen delivery is impaired due to anemia, especially during times of increased metabolic demand, and cerebral blood flow (CBF) must increase to meet changing physiologic needs. But hyperemia limits cerebrovas…
View article: Regional glia-related metabolite levels are higher at older age and scale negatively with visuo-spatial working memory: A cross-sectional proton MR spectroscopy study at 7 tesla on normal cognitive ageing
Regional glia-related metabolite levels are higher at older age and scale negatively with visuo-spatial working memory: A cross-sectional proton MR spectroscopy study at 7 tesla on normal cognitive ageing Open
Proton MR spectroscopy ( 1 H-MRS) has been used to assess regional neurochemical brain changes during normal ageing, but results have varied. Exploiting the increased sensitivity at ultra-high field strength, we performed 1 H-MRS in 60 hea…
View article: Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion
Cortical microinfarcts in memory clinic patients are associated with reduced cerebral perfusion Open
Cerebral cortical microinfarcts (CMIs) are small ischemic lesions associated with cognitive impairment and dementia. CMIs are frequently observed in cortical watershed areas suggesting that hypoperfusion contributes to their development. W…
View article: Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI
Quantification of cerebral perfusion and cerebrovascular reserve using Turbo‐QUASAR arterial spin labeling MRI Open
Purpose To compare cerebral blood flow (CBF) and cerebrovascular reserve (CVR) quantification from Turbo‐QUASAR (quantitative signal targeting with alternating radiofrequency labeling of arterial regions) arterial spin labeling (ASL) and s…
View article: European Ultrahigh‐Field Imaging Network for Neurodegenerative Diseases (EUFIND)
European Ultrahigh‐Field Imaging Network for Neurodegenerative Diseases (EUFIND) Open
Introduction The goal of European Ultrahigh‐Field Imaging Network in Neurodegenerative Diseases (EUFIND) is to identify opportunities and challenges of 7 Tesla (7T) MRI for clinical and research applications in neurodegeneration. EUFIND co…
View article: PF742 CEREBRAL OXYGEN METABOLISM MEASUREMENTS WITH MRI IN ADULTS WITH SICKLE CELL DISEASE
PF742 CEREBRAL OXYGEN METABOLISM MEASUREMENTS WITH MRI IN ADULTS WITH SICKLE CELL DISEASE Open
Background: MRI studies have demonstrated a high prevalence of silent cerebral infarcts (SCI) in both children and adults with sickle cell disease (SCD). SCI are associated with cognitive impairment and lesion progression in adults with SC…
View article: Correction to: Ultra-high field MR angiography in human migraine models: a 3.0 T/7.0 T comparison study
Correction to: Ultra-high field MR angiography in human migraine models: a 3.0 T/7.0 T comparison study Open
After publication of the original article [1], the authors have notified us that an updated version of Figures 1, 2 and 3 should have been published. The incorrect and revised figures can be found below.