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View article: Predictors of and reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme
Predictors of and reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme Open
Objective: The study aimed to assess the predictors and the reasons for refusal to participate in a digitally supported remote maintenance pulmonary rehabilitation programme (M-PRP). Methods: Patients contacted to integrate a 12-month M-PR…
View article: Effect of dyspnoea-oriented hypnosis as an adjunct to pulmonary rehabilitation on the affective dimension of dyspnoea and physical activity level: a randomized controlled trial
Effect of dyspnoea-oriented hypnosis as an adjunct to pulmonary rehabilitation on the affective dimension of dyspnoea and physical activity level: a randomized controlled trial Open
Background Pulmonary rehabilitation (PR) has limited long-term effects on physical activity (PA) levels in patients with COPD. Dyspnoea-related anxiety, part of the affective dimension of dyspnoea, is a major barrier to PA. This study asse…
View article: Safety and Efficacy of Pulmonary Rehabilitation for Long COVID Patients Experiencing Long-Lasting Symptoms
Safety and Efficacy of Pulmonary Rehabilitation for Long COVID Patients Experiencing Long-Lasting Symptoms Open
Due to the high prevalence and persistence of long COVID, it is important to evaluate the safety and efficacy of pulmonary rehabilitation (PR) for patients who experience long-lasting symptoms more than six months after initial COVID-19 on…
View article: Relevance of multidimensional dyspnea assessment in the context of pulmonary rehabilitation
Relevance of multidimensional dyspnea assessment in the context of pulmonary rehabilitation Open
Objectives: While dyspnea is the main symptom in chronic obstructive pulmonary disease (COPD), it is often inadequately evaluated in pulmonary rehabilitation (PR), as it is typically measured using only the impact dimension (ID). However, …
View article: Fatty Acid Hydroxytyrosyl Esters of Olive Oils Are Bioaccessible According to Simulated <i>In Vitro</i> Gastrointestinal Digestion: Unraveling the Role of Digestive Enzymes on Their Stability
Fatty Acid Hydroxytyrosyl Esters of Olive Oils Are Bioaccessible According to Simulated <i>In Vitro</i> Gastrointestinal Digestion: Unraveling the Role of Digestive Enzymes on Their Stability Open
Recently, new bioactive compounds were identified in olive oil, lipophenols, which are composed of a fatty acid (FA) and a phenolic core, such as HT (HT-FA). However, their bioaccessibility remains unknown. Thus, the present study uncovers…
View article: Unravelling the capacity of hydroxytyrosol and its lipophenolic derivates to modulate the H2O2-induced isoprostanoid profile of THP-1 monocytes by UHPLC-QqQ-MS/MS lipidomic workflow
Unravelling the capacity of hydroxytyrosol and its lipophenolic derivates to modulate the H2O2-induced isoprostanoid profile of THP-1 monocytes by UHPLC-QqQ-MS/MS lipidomic workflow Open
View article: New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration
New lipophenols prevent carbonyl and oxidative stresses involved in macular degeneration Open
View article: Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy
Preclinical pharmacology of a lipophenol in a mouse model of light-induced retinopathy Open
View article: Targeted Lipidomics Profiling Reveals the Generation of Hydroxytyrosol-Fatty Acids in Hydroxytyrosol-Fortified Oily Matrices: New Analytical Methodology and Cytotoxicity Evaluation
Targeted Lipidomics Profiling Reveals the Generation of Hydroxytyrosol-Fatty Acids in Hydroxytyrosol-Fortified Oily Matrices: New Analytical Methodology and Cytotoxicity Evaluation Open
Lipophenols have been stressed as an emerging class of functional compounds. However, little is known about their diversity. Thus, this study is aimed at developing a new method for the extraction, cleanup, and ultrahigh-performance liquid…
View article: Isopropyl‐phloroglucinol‐DHA protects outer retinal cells against lethal dose of all‐ <i>trans</i> ‐retinal
Isopropyl‐phloroglucinol‐DHA protects outer retinal cells against lethal dose of all‐ <i>trans</i> ‐retinal Open
All‐ trans ‐retinal (a t RAL) is a highly reactive carbonyl specie, known for its reactivity on cellular phosphatidylethanolamine in photoreceptor. It is generated by photoisomerization of 11‐ cis ‐retinal chromophore linked to opsin by th…
View article: New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells
New Lipophenol Antioxidants Reduce Oxidative Damage in Retina Pigment Epithelial Cells Open
Age-related macular degeneration (AMD) is a multifactorial pathology and its progression is exacerbated by oxidative stress. Oxidation and photo-oxidation reactions modify lipids in retinal cells, contribute to tissue injury, and lead to t…
View article: Imidazo[1,2-b]pyridazines targeting TgCDPK1 as new anti-<em>Toxoplasma gondii</em> chemotherapeutic treatments
Imidazo[1,2-b]pyridazines targeting TgCDPK1 as new anti-<em>Toxoplasma gondii</em> chemotherapeutic treatments Open
View article: Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1
Development of new highly potent imidazo[1,2-b]pyridazines targeting Toxoplasma gondii calcium-dependent protein kinase 1 Open