Espoir Bwenge Malembaka
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View article: Correction: Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis
Correction: Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis Open
[This corrects the article DOI: 10.1371/journal.pmed.1004286.].
View article: Protection from killed whole-cell cholera vaccines: a systematic review and meta-analysis
Protection from killed whole-cell cholera vaccines: a systematic review and meta-analysis Open
Bill & Melinda Gates Foundation.
View article: Three Cases of Vertical Transmission of Clade Ib Mpox Virus
Three Cases of Vertical Transmission of Clade Ib Mpox Virus Open
View article: Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democratic Republic of the Congo
Challenges with achieving and maintaining oral cholera vaccine coverage: insights from serial cross-sectional representative surveys in a cholera-endemic community in the Democratic Republic of the Congo Open
Background We conducted three serial cross-sectional representative surveys after a mass cholera vaccination campaign in Uvira, Democratic Republic of the Congo to (1) estimate the vaccination coverage and explore heterogeneity by geograph…
View article: Epidemiological and Clinical Features of Mpox during the Clade Ib Outbreak in South-Kivu, Democratic Republic of the Congo: a Prospective Cohort Study
Epidemiological and Clinical Features of Mpox during the Clade Ib Outbreak in South-Kivu, Democratic Republic of the Congo: a Prospective Cohort Study Open
Background Clade Ib, a new strain of the Clade I monkeypox virus, emerged in Eastern Democratic Republic of the Congo, sparking an international outbreak. Comprehensive studies are needed to assess its transmission dynamics and clinical pr…
View article: Multicountry genomic analysis underscores regional cholera spread in Africa
Multicountry genomic analysis underscores regional cholera spread in Africa Open
Cholera remains a significant public health burden in many countries in sub-Saharan Africa, though the exact mechanisms of bacterial emergence and spread remain largely undefined. We generated genomic data from 763 Vibrio cholerae O1 isola…
View article: Process evaluation of an urban piped water supply infrastructure improvement programme in Uvira, Democratic Republic of the Congo
Process evaluation of an urban piped water supply infrastructure improvement programme in Uvira, Democratic Republic of the Congo Open
Major investments in water supply infrastructure will be required to achieve Sustainable Development Goal (SDG) 6. Safely managed water services are also central to global cholera and diarrhoeal diseases prevention strategies. However, evi…
View article: Economic cost of a case of diarrhoea in Uvira, Democratic Republic of the Congo: A cost of illness study
Economic cost of a case of diarrhoea in Uvira, Democratic Republic of the Congo: A cost of illness study Open
Background Diarrhoea is one of the leading causes of disability-adjusted life years (DALYs) among children below five years, though the proportion of the burden occurring amongst those aged over 70 is increasing. The cost of treating and m…
View article: Association between stunting and fecal calprotectin levels in breastfed infants living in a rural area of the Democratic Republic of the Congo: a cross sectional study
Association between stunting and fecal calprotectin levels in breastfed infants living in a rural area of the Democratic Republic of the Congo: a cross sectional study Open
Background: Stunting is a major public health problem in low- and middle-income countries as in Democratic Republic of the Congo (DRC). Many factors, such as environmental enteric dysfunction (EED), are incriminated in the pathogenesis of …
View article: Publisher Correction: Maternal preconceptional and prenatal exposure to El Niño Southern Oscillation levels and child mortality: a multi-country study
Publisher Correction: Maternal preconceptional and prenatal exposure to El Niño Southern Oscillation levels and child mortality: a multi-country study Open
View article: Protection from Killed Whole-Cell Cholera Vaccines: A Systematic Review and Meta-Analysis
Protection from Killed Whole-Cell Cholera Vaccines: A Systematic Review and Meta-Analysis Open
Summary Background Killed whole-cell oral cholera vaccines (kOCVs) are a standard prevention and control measure in cholera endemic areas, outbreaks, and humanitarian emergencies. Recently, new evidence has emerged and the ways in which th…
View article: Maternal preconceptional and prenatal exposure to El Niño Southern Oscillation levels and child mortality: a multi-country study
Maternal preconceptional and prenatal exposure to El Niño Southern Oscillation levels and child mortality: a multi-country study Open
View article: Author Correction: Enhanced cholera surveillance to improve vaccination campaign efficiency
Author Correction: Enhanced cholera surveillance to improve vaccination campaign efficiency Open
View article: Improved water supply infrastructure to reduce acute diarrhoeal diseases and cholera in Uvira, Democratic Republic of the Congo: Results and lessons learned from a pragmatic trial
Improved water supply infrastructure to reduce acute diarrhoeal diseases and cholera in Uvira, Democratic Republic of the Congo: Results and lessons learned from a pragmatic trial Open
Background Safely managed drinking water is critical to prevent diarrhoeal diseases, including cholera, but evidence on the effectiveness of piped water supply in reducing these diseases in low-income and complex emergency settings remains…
View article: Shifting transmission patterns of human mpox in South Kivu, DR Congo
Shifting transmission patterns of human mpox in South Kivu, DR Congo Open
View article: Evaluating the risk of conflict on recent Ebola outbreaks in Guinea and the Democratic Republic of the Congo
Evaluating the risk of conflict on recent Ebola outbreaks in Guinea and the Democratic Republic of the Congo Open
Background Reducing Ebola virus transmission relies on the ability to identify cases and limit contact with infected bodily fluids through biosecurity, safe sex practices, safe burial and vaccination. Armed conflicts can complicate outbrea…
View article: Exploring different health care providers´ perceptions on the management of diarrhoea in cholera hotspots in the Democratic Republic of Congo: A qualitative content analysis
Exploring different health care providers´ perceptions on the management of diarrhoea in cholera hotspots in the Democratic Republic of Congo: A qualitative content analysis Open
Global cholera guidelines support wider healthcare system strengthening interventions, alongside vertical outbreak responses, to end cholera. Well-trained healthcare providers are essential for a resilient health system and can create syne…
View article: Facility capacity and provider knowledge for cholera surveillance and diarrhoea case management in cholera hotspots in the Democratic Republic of Congo – a mixed-methods study
Facility capacity and provider knowledge for cholera surveillance and diarrhoea case management in cholera hotspots in the Democratic Republic of Congo – a mixed-methods study Open
Increasing awareness of cholera case definitions in this context could help improve cholera surveillance and control. Increased support and supervision, especially for private providers, could help ensure facilities are equipped to provide…
View article: Enhanced cholera surveillance to improve vaccination campaign efficiency
Enhanced cholera surveillance to improve vaccination campaign efficiency Open
View article: Cholera Deaths During Outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10–35 Months After Mass Vaccination
Cholera Deaths During Outbreaks in Uvira, Eastern Democratic Republic of the Congo, 10–35 Months After Mass Vaccination Open
Our understanding of the burden and drivers of cholera mortality is hampered by limited surveillance and confirmation capacity. Leveraging enhanced clinical and laboratory surveillance in the cholera-endemic community of Uvira, eastern Dem…
View article: Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: a matched case-control study
Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: a matched case-control study Open
Wellcome Trust and Gavi, the Vaccine Alliance.
View article: Challenges with Achieving and Maintaining High Oral Cholera Vaccine Coverage in Uvira, The Democratic Republic of the Congo: serial cross-sectional representative surveys
Challenges with Achieving and Maintaining High Oral Cholera Vaccine Coverage in Uvira, The Democratic Republic of the Congo: serial cross-sectional representative surveys Open
BackgroundMaximizing the impact of the limited global supply of killed oral cholera vaccines (kOCVs) requires understanding the barriers to achieving high population coverage during vaccination campaigns as well as factors that may influen…
View article: Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis
Estimating the proportion of clinically suspected cholera cases that are true Vibrio cholerae infections: A systematic review and meta-analysis Open
Background Cholera surveillance relies on clinical diagnosis of acute watery diarrhea. Suspected cholera case definitions have high sensitivity but low specificity, challenging our ability to characterize cholera burden and epidemiology. O…
View article: Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: A matched case-control study
Effectiveness of one dose of killed oral cholera vaccine in an endemic community in the Democratic Republic of the Congo: A matched case-control study Open
Background A global shortage of cholera vaccines has increased the use of single-dose regimens, rather than the standard two-dose regimen. There is limited evidence on single-dose protection, particularly in children. In 2020, a mass vacci…
View article: Process evaluation of an urban piped water supply infrastructure improvement programme in a cholera hotspot
Process evaluation of an urban piped water supply infrastructure improvement programme in a cholera hotspot Open
Large-scale investments in water supply infrastructure will be required to achieve Sustainable Development Goal (SDG) 6. Safely managed water services are also a central element of global strategies to prevent cholera and diarrhoeal diseas…
View article: Improved water supply infrastructure to reduce acute diarrhoeal diseases and cholera in Uvira, Democratic Republic of the Congo: results and lessons learned from a pragmatic trial
Improved water supply infrastructure to reduce acute diarrhoeal diseases and cholera in Uvira, Democratic Republic of the Congo: results and lessons learned from a pragmatic trial Open
Safely managed drinking water is critical to prevent diarrhoeal diseases, including cholera, but evidence on the effectiveness of piped water supply in reducing these diseases in low-income and complex emergency settings remains scarce. We…
View article: Water, Sanitation, and Cholera in Sub-Saharan Africa
Water, Sanitation, and Cholera in Sub-Saharan Africa Open
Improvements in water and sanitation should reduce cholera risk though the associations between cholera and specific water and sanitation access measures remain unclear. We estimated the association between eight water and sanitation measu…
View article: A fuzzy inference-based index for piped water supply service quality in a complex, low-income urban setting
A fuzzy inference-based index for piped water supply service quality in a complex, low-income urban setting Open
Sustainable Development Goal (SDG) 6 calls for universal access to safely managed drinking water services. We studied the evolution of the water supply service between January 2017 and December 2021 in the town of Uvira (South Kivu, Democr…
View article: Cholera deaths during outbreaks in Uvira, eastern Democratic Republic of the Congo, 10-35 months after mass vaccination
Cholera deaths during outbreaks in Uvira, eastern Democratic Republic of the Congo, 10-35 months after mass vaccination Open
Our understanding of the burden and drivers of cholera mortality is hampered by limited surveillance and confirmation capacity. Leveraging enhanced clinical and laboratory surveillance in the cholera-endemic community of Uvira, eastern Dem…
View article: Evaluating the Risk of Conflict on Recent Ebola Outbreaks in Guinea and the Democratic Republic of the Congo
Evaluating the Risk of Conflict on Recent Ebola Outbreaks in Guinea and the Democratic Republic of the Congo Open
Background Reducing Ebola virus transmission relies on the ability to identify cases and limit contact with infected bodily fluids through biosecurity, safe sex practices, safe burial and vaccination. Armed conflicts can complicate outbrea…