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View article: Management of CMV encephalitis with persistent CSF CMV DNA in a patient with HIV: a case report of successful treatment with ganciclovir–foscarnet combination therapy
Management of CMV encephalitis with persistent CSF CMV DNA in a patient with HIV: a case report of successful treatment with ganciclovir–foscarnet combination therapy Open
Background Cytomegalovirus (CMV) is a common opportunistic pathogen in immunocompromised individuals and can lead to significant mortality and morbidity via end-organ involvements. CMV related multiorgan involvement including encephalitis …
View article: Management of CMV encephalitis in an HIV-positive patient with persistent CSF CMV viremia; successful treatment with ganciclovir–foscarnet combination therapy: A case report
Management of CMV encephalitis in an HIV-positive patient with persistent CSF CMV viremia; successful treatment with ganciclovir–foscarnet combination therapy: A case report Open
Background Cytomegalovirus (CMV) is a common opportunistic pathogen in immunocompromised individuals and can lead to significant mortality and morbidity via end-organ involvements. CMV related multiorgan involvement including encephalitis …
View article: Meningitis Caused by Extensively Drug-Resistant Acinetobacter baumannii: Treatment Options and Factors Affecting Outcomes
Meningitis Caused by Extensively Drug-Resistant Acinetobacter baumannii: Treatment Options and Factors Affecting Outcomes Open
Introduction In this study, we analyzed the clinical features of nosocomial meningitis caused by Acinetobacter baumannii (A. baumannii) to identify the factors affecting the outcome and compared the effectiveness of different therapeutic r…
View article: Development and evaluation of an antigen targeting lateral flow test for Crimean-Congo Haemorrhagic Fever
Development and evaluation of an antigen targeting lateral flow test for Crimean-Congo Haemorrhagic Fever Open
The Liverpool School of Tropical Medicine, National Institute for Health Research Health Protection Research Unit in Emerging Zoonotic Infections, The Medical Research Council and The Pandemic Institute.
View article: The Outcomes of COVID-19 Patients with ARDS Who Received High Flow Nasal Oxygen in Medical Wards Outside Intensive Care Units Under Supervision of Non-intensivists.
The Outcomes of COVID-19 Patients with ARDS Who Received High Flow Nasal Oxygen in Medical Wards Outside Intensive Care Units Under Supervision of Non-intensivists. Open
Objective: Efficacy of high flow nasal oxygen (HFNO) use in COVID-19 patients who developed ARDS in medical wards is poorly studied. We aimed to investigate whether use of HFNO in wards outside intensive care unit under supervision of non-…
View article: Evaluation of risk factors for the development of bacteremia and complications in patients with brucellosis: Is it possible to predict the clinical course?
Evaluation of risk factors for the development of bacteremia and complications in patients with brucellosis: Is it possible to predict the clinical course? Open
Introduction: Brucellosis is often confused with other diseases or accompanies the conditions it imitates. It causes treatment delays, failure, relapse, and complications. This study aimed to investigate bacteremia and complication predict…
View article: Clinical Importance of Immunophenotyping of Peripheral Blood Lymphocyte Subsets in Adult COVID-19 Patients: A Cross-Sectional Study
Clinical Importance of Immunophenotyping of Peripheral Blood Lymphocyte Subsets in Adult COVID-19 Patients: A Cross-Sectional Study Open
ÖZGiriş: Koronavirüs hastalığı-2019, hafif ateş ve öksürük gibi semptomlarla veya sitokin fırtınası ve solunum yetmezliği gibi semptomlarla ortaya çıkabilir.Bu nedenle patogenezi araştırılmaya devam etmektedir.Bu çalışmada, COVID-19 hastal…
View article: Evaluation Of Adult Extrapulmonary Tuberculosis Patients
Evaluation Of Adult Extrapulmonary Tuberculosis Patients Open
Objective: Extrapulmonary tuberculosis (EPTB) can be easily missed due to challenges in diagnosis or overlooked in the differential diagnosis. Therefore, EPTB should be considered in endemic regions, especially in the differential diagnosi…
View article: Urinary tract infections caused by carbapenem-resistant Klebsiella pneumonia: monotherapy or combined therapy?
Urinary tract infections caused by carbapenem-resistant Klebsiella pneumonia: monotherapy or combined therapy? Open
Purpose: In this study, we evaluated healthcare-associated urinary tract infections caused by carbapenem-resistant Klebsiella pneumoniae.
Materials and methods: The study included 134 patients, diagnosed with healthcare-associated urinar…
View article: Determination of risk factors playing a role in the transmission of COVID-19 in healthcare professionals
Determination of risk factors playing a role in the transmission of COVID-19 in healthcare professionals Open
Introduction: Healthcare workers and professionals have the highest risk of transmission of novel coronavirus disease-2019 (COVID-19). The risks faced by healthcare professionals can vary according to their working conditions, knowledge, a…
View article: Late presentations among HIV-infected patients
Late presentations among HIV-infected patients Open
Objective: The late diagnosis of human immunodeficiency virus (HIV) infection and, therefore, initiation of antiretroviral therapy(ART) in the advanced stages of the disease is still a significant problem in many countries. This study aime…
View article: Evaluation of Healthcare Professionals’ Knowledge Level, Attitude and Use of Personal Protective Equipment about COVID-19
Evaluation of Healthcare Professionals’ Knowledge Level, Attitude and Use of Personal Protective Equipment about COVID-19 Open
Amaç: COVID-19 hastalarına bakım veren sağlık çalışanları, infeksiyon açısından yüksek riskli kabul edilmekte ve korunmaları en önemli önceliklerden biri olarak değerlendirilmektedir.Sağlık çalışanlarının hastalık hakkında yetersiz bilgiye…
View article: Concurrent use of drugs and potential drug interactions in HIV-infected patients in a tertiary healthcare facility in Turkey
Concurrent use of drugs and potential drug interactions in HIV-infected patients in a tertiary healthcare facility in Turkey Open
Purpose: To investigate the frequency of concurrent drug use and drug interactions in patients with human immunodeficiency virus (HIV) infection.
Methods: The medical records of HIV-infected patients followed up at Ondokuz Mayis Universit…
View article: CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report
CARD9 Mutation in a Patient with Candida albicans Meningoencephalitis; A Case Report Open
Primary immunodeficiencies are disorders that cause clinical findings ranging from mild diseases to life-threatening diseases in a wide age range. Infections are the most common complications of primary immunodeficiencies. Caspase associat…
View article: Pneumocystis Jirovecii Pneumonia In HIV-Infected Patients: A Single Center Experience
Pneumocystis Jirovecii Pneumonia In HIV-Infected Patients: A Single Center Experience Open
Objective: Pneumocystis jirovecii pneumonia (PCP) is still a critical opportunistic infection in patients diagnosed with the human immunodeficiency (HIV) infection in the advanced stages and patients who do not adhere to antiretroviral the…
View article: Mycobacterium tuberculosis Infections in HIV-infected Patients
Mycobacterium tuberculosis Infections in HIV-infected Patients Open
Introduction: Tuberculosis (TB) still continues to be the leading cause of death for Human Immunodeficiency Virus (HIV) infected patients, and it accounts for approximately one of three acquired immunodeficiency syndrome (AIDS) related dea…
View article: Effects of Different Direct Acting Antivirals on Quality of life of Patients with Chronic Hepatitis C
Effects of Different Direct Acting Antivirals on Quality of life of Patients with Chronic Hepatitis C Open
Introduction: Chronic hepatitis C is an infectious disease known to affect people worldwide. The disease is characterized by both hepatic and extrahepatic manifestations that impair the patient’s overall quality of life (QoL). Potent and e…
View article: Evaluation of the Effectiveness of Direct-Acting Antiviral Agents in Patients With Hepatitis C
Evaluation of the Effectiveness of Direct-Acting Antiviral Agents in Patients With Hepatitis C Open
Amaç: Hepatit C virusu (HCV) infeksiyonu kişisel, toplumsal ve ekonomik etkisi olan küresel bir sorundur.HCV ile infekte hastaların %85'e varan kısmında virus klirensi sağlanamamakta ve gelişen kronik infeksiyon sonucu hastalarda siroz, he…
View article: Enterococcus hirae as a cause of bacteremic urinary tract infection: first case report from Turkey
Enterococcus hirae as a cause of bacteremic urinary tract infection: first case report from Turkey Open
Introduction: Enterococcus hirae (E. hirae) constitutes less than 1% of the enterococci strains in human clinical specimens. In this article, we report the first case of urinary tract infection-related bacteremia due to E. hirae from Turke…
View article: Toxocariasis Presenting with Hypereosinophilia and Lymphadenopathy: A Case Report
Toxocariasis Presenting with Hypereosinophilia and Lymphadenopathy: A Case Report Open
Human toxocariasis is a parasitic disease transmitted to humans by ingestion of Toxocara spp. larvae. Rural area residents and children have higher risk for this parasitic infection. The disease is frequently asymptomatic; however, it may …
View article: Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey
Seroprevalence of hepatitis A virus, hepatitis B virus, hepatitis C virus, and syphilis among human immunodeficiency virus-infected people at a university hospital, Turkey Open
Introduction Infections such as viral hepatitis and syphilis that share similar transmission routes with human immunodeficiency virus (HIV) may adversely affect the course of the disease. We aimed to determine the seroprevalence of viral h…
View article: Acute Kidney Injury in a Patient Receiving Antimalarial Therapy: A Case Report
Acute Kidney Injury in a Patient Receiving Antimalarial Therapy: A Case Report Open
In this article, we present a case of Plasmodium falciparum malaria in a male patient who developed acute kidney injury during antimalarial treatment. A 38-years-old Turkish male patient was admitted to the emergency department with the co…
View article: HIV/AIDS Cohort Evaluation of a Single Center in the Context of “90-90-90” Targets
HIV/AIDS Cohort Evaluation of a Single Center in the Context of “90-90-90” Targets Open
Objective: Human immunodeficiency virus/acquired immune deficiency syndrome (HIV/AIDS) continues to be one of the most important health, social and safety issues faced by the global community.In 2014, the United Nations HIV/AIDS joint prog…
View article: Investigation of infections after renal transplantation
Investigation of infections after renal transplantation Open
Amaç: Böbrek nakli sonrası erken dönemde gelişen infeksiyonlar yoğun immunsupresyon varlığında kişinin hayatını tehdit edebilmektedir. Bu dönemde en sık üriner sistem infeksiyonları görülmekle birlikte diğer sistemlerin de detaylı bir şeki…
View article: Cryptococcal Meningoencephalitis Treated with Fingolimod in a Patient with Multiple Sclerosis
Cryptococcal Meningoencephalitis Treated with Fingolimod in a Patient with Multiple Sclerosis Open
Cryptococcus neoformans is an opportunistic fungal agent, which may cause infection depending on the state of immunity. The agent is especially prone to be localized in the central nervous system. Fingolimod is an immunomodulatory drug tha…
View article: Aetiology of PCR negative suspected Crimean-Congo hemorrhagic fever cases in an endemic area
Aetiology of PCR negative suspected Crimean-Congo hemorrhagic fever cases in an endemic area Open
Crimean-Congo hemorrhagic fever (CCHF) is a potentially fatal tick-borne viral infection that is widely distributed worldwide. The diagnosis is frequently missed due to the non-specific initial symptoms and the differential diagnosis inclu…
View article: Infective endocarditis with atypical clinical feature and relapse by Abiotrophia defectiva
Infective endocarditis with atypical clinical feature and relapse by Abiotrophia defectiva Open
A case of infective endocarditis caused by an uncommon agent Abiotrophia defectiva with atypical manifestations is presented. A 42-year-old woman previously had rheumatic heart disease, presented with the symptoms of fever and chills that …