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View article: Removing genetic effects on plasma proteins enhances their utility as disease biomarkers
Removing genetic effects on plasma proteins enhances their utility as disease biomarkers Open
Plasma protein levels are influenced by both genetic and non-genetic factors and can serve as early disease biomarkers. When a protein is correlated with, but not causally linked to, disease, its genetic determinants can add unwanted varia…
View article: Selected miRNAs in Urinary Extracellular Vesicles Show Promise for Early and Specific Diagnostics of Diabetic Kidney Disease
Selected miRNAs in Urinary Extracellular Vesicles Show Promise for Early and Specific Diagnostics of Diabetic Kidney Disease Open
Diabetic kidney disease (DKD) is a health burden that lacks specific and early diagnostic biomarkers. For their discovery, we sequenced urinary extracellular vesicle miRNAs in a type 1 diabetes cohort of males with and without DKD. The res…
View article: Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker
Deep learning-based prediction of one-year mortality in Finland is an accurate but unfair aging marker Open
View article: Risk factors for severe respiratory syncytial virus infection during the first year of life: development and validation of a clinical prediction model
Risk factors for severe respiratory syncytial virus infection during the first year of life: development and validation of a clinical prediction model Open
Sigrid Jusélius Foundation, European Research Council, Pediatric Research Foundation, and Academy of Finland.
View article: Deep learning-based prediction of one-year mortality in the entire Finnish population is an accurate but unfair digital marker of aging
Deep learning-based prediction of one-year mortality in the entire Finnish population is an accurate but unfair digital marker of aging Open
Background Accurately predicting short-term mortality is important for optimizing healthcare resource allocation, developing risk-reducing interventions, and improving end-of-life care. Moreover, short-term mortality risk reflects individu…
View article: ICT Engineering Students’ Perceptions on Project-Based Online Learning in Community of Inquiry (CoI)
ICT Engineering Students’ Perceptions on Project-Based Online Learning in Community of Inquiry (CoI) Open
Industry and higher education are increasingly utilizing online environments due to digitalization. As a result, the learning experiences in these new digital learning ecosystems as communities must be re-examined critically. This study in…
View article: Data Resource Profile: Nationwide registry data for high-throughput epidemiology and machine learning (FinRegistry)
Data Resource Profile: Nationwide registry data for high-throughput epidemiology and machine learning (FinRegistry) Open
View article: Risk factors for severe respiratory syncytial virus infection during the first year of life: development and validation of a clinical prediction model
Risk factors for severe respiratory syncytial virus infection during the first year of life: development and validation of a clinical prediction model Open
Background Novel immunisation methods against respiratory syncytial virus (RSV) are emerging, but knowledge of risk factors for severe RSV disease is insufficient for their optimal targeting. We aimed to identify predictors for RSV hospita…