Explanipedia

Effects of super high-flux vitamin E–coated and medium cut-off dialyzers on uremic toxins removal and biocompatibility: the E-FLUX randomized controlled study Open

Mohamed Belmouaz, Etienne Cogne, Florent Joly, Fabien Duthé, Éstelle Desport , et al. · 2025

Background Medium cut-off hemodialysis (MCO-HD) improves removal of middle molecules (MM) uremic toxins. The effects of the novel super high-flux vitamin E–coated (SHFVE) dialyzer on MM removal and biocompatibility parameters including inf…

B01 VENETOCLAX TARGETED THERAPY in AL AMYLOIDOSIS PATIENTS: A RETROSPECTIVE ANALYSIS FROM THE FRENCH AMYLOIDOSIS NETWORK Open

Murielle Roussel, Michelle Pirotte, Romain Gounot, K. Queru, Oscar Rizzo , et al. · 2023

Background: BCL-2 inhibition represents a promising therapeutic approach in multiple myeloma (MM). Venetoclax (VEN) is an oral BCL-2-selective BH3 mimetic and is currently approved in CLL. VEN has shown activity in MM cell lines with t(11;…

Diagnosis and risk factors for intracranial aneurysms in autosomal polycystic kidney disease: a cross-sectional study from the Genkyst cohort Open

Siriane Lefèvre, Marie‐Pierre Audrézet, Jean‐Michel Halimi, Hélène Longuet, Frank Bridoux , et al. · 2022

Background Autosomal dominant polycystic kidney disease (ADPKD) is associated with an increased risk for developing intracranial aneurysms (IAs). We aimed to evaluate the frequency of diagnosis of IAs in the cross-sectional, population-bas…

Randall-Type Monoclonal Immunoglobulin Deposition Disease: New Insights into the Pathogenesis, Diagnosis and Management Open

Camille Cohen, Florent Joly, Audrey Sibille, Vincent Javaugue, Éstelle Desport , et al. · 2021

Randall-type monoclonal immunoglobulin deposition disease (MIDD) is a rare disease that belongs to the spectrum of monoclonal gammopathy of renal significance (MGRS). Renal involvement is prominent in MIDD, but extra-renal manifestations c…

Randall-type monoclonal immunoglobulin deposition disease: description of cardiac involvement Open

A Ramonatxo, R. Ortiz García, Florent Joly, Bruno Degand, Nicolas Bidegain , et al. · 2020

Background Randall-type monoclonal immunoglobulin disease (MIDD) is a rare complication of a monoclonal plasma cell clone. MIDD differs from AL amyloidosis by the presence of Congo red negative non-organized immunoglobulin (Ig) deposits, m…

Effect of Expanded Hemodialysis on Body Composition and Nutritional Status Open

Mohamed Belmouaz, Marc Bauwens, Éstelle Desport, P Jamet, Frank Bridoux · 2020

New clinical forms of hereditary apoA-I amyloidosis entail both glomerular and retinal amyloidosis Open

Magali Colombat, Jean‐Claude Aldigier, Pierre-Raphaël Rothschild, Vincent Javaugue, Éstelle Desport , et al. · 2020

Monoclonal Gammopathy of Renal Significance Open

Vincent Javaugue, Céline Debiais-Delpech, Éstelle Desport, Laure Écotière, Jean‐Paul Fermand , et al. · 2020

Monoclonal gammopathy of renal significance. The term "monoclonal gammopathy of renal significance" regroups all renal disorders caused by a monoclonal immunoglobulin (Ig) secreted by a nonmalignant B-cell clone. However, a small clone can…

MP530COMPARISON OF HEMODIALYSIS WITH MEDIUM CUT-OFF DIALYZER AND ONE-LINE HEMODIAFILTRATION ON THE REMOVAL OF SMALL AND MIDDLE SIZE MOLECULES: A PILOT STUDY Open

Mohamed Belmouaz, Jeremy Diolez, Marc Bauwens, Laure Écotière, Éstelle Desport , et al. · 2017

RESULTS:TheranovaV R was well accepted by all the patients and no adverse events were reported.The main results, reported in table 1, showed a high removal rate for all the uremic toxins analyzed.The albumin level was measured before and a…

Prognostic value of kidney biopsy in myeloma cast nephropathy: a retrospective study of 70 patients Open

Laure Écotière, Antoine Thierry, Céline Debiais-Delpech, Sylvie Chevret, Vincent Javaugue , et al. · 2016

In the published version of this paper the first and second sentences of the 'Patients' section ('This study was done in accordance with the Declaration of Helsinki.Written informed consent was obtained from all study participants.Seventy …

Prognostic value of kidney biopsy in myeloma cast nephropathy: a retrospective study of 70 patients Open

Laure Écotière, Antoine Thierry, Céline Debiais-Delpech, Sylvie Chevret, Vincent Javaugue , et al. · 2015

In MCN, the presence of numerous casts and diffuse tubular atrophy is associated with poor renal prognosis. These data suggest that additional strategies to reduce FLC burden should be considered in patients with extensive cast formation.

Mutation Update of the<i>CLCN5</i>Gene Responsible for Dent Disease 1 Open

Lamisse Mansour‐Hendili, Anne Blanchard, Nelly Le Pottier, Isabelle Roncelin, Stéphane Lourdel , et al. · 2015

Dent disease is a rare X-linked tubulopathy characterized by low molecular weight proteinuria, hypercalciuria, nephrocalcinosis and/or nephrolithiasis, progressive renal failure, and variable manifestations of other proximal tubule dysfunc…

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