Ester Canepa
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View article: Physical determinants of nanoparticle-mediated lipid membrane fusion
Physical determinants of nanoparticle-mediated lipid membrane fusion Open
The interplay between nanoparticle size and membrane curvature plays a key role in regulating synthetic nanoparticle-mediated membrane fusion.
View article: Cholesterol‐Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery
Cholesterol‐Containing Liposomes Decorated With Au Nanoparticles as Minimal Tunable Fusion Machinery Open
Membrane fusion is essential for the basal functionality of eukaryotic cells. In physiological conditions, fusion events are regulated by a wide range of specialized proteins, operating with finely tuned local lipid composition and ionic e…
View article: Cholesterol-containing liposomes decorated with Au nanoparticles as minimal tunable fusion machinery
Cholesterol-containing liposomes decorated with Au nanoparticles as minimal tunable fusion machinery Open
Membrane fusion is essential for the basal functionality of eukaryotic cells. In physiological conditions, fusion events are regulated by a wide range of specialized proteins, as well as by a finely tuned local lipid composition and ionic …
View article: Amphiphilic Gold Nanoparticles: A Biomimetic Tool to Gain Mechanistic Insights into Peptide-Lipid Interactions
Amphiphilic Gold Nanoparticles: A Biomimetic Tool to Gain Mechanistic Insights into Peptide-Lipid Interactions Open
Functional peptides are now widely used in a myriad of biomedical and clinical contexts, from cancer therapy and tumor targeting to the treatment of bacterial and viral infections. Underlying this diverse range of applications are the non-…
View article: Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes
Cholesterol Hinders the Passive Uptake of Amphiphilic Nanoparticles into Fluid Lipid Membranes Open
Plasma membranes represent pharmacokinetic barriers for the passive transport of site-specific drugs within cells. When engineered nanoparticles (NPs) are considered as transmembrane drug carriers, the plasma membrane composition can affec…
View article: Amphiphilic gold nanoparticles perturb phase separation in multidomain lipid membranes
Amphiphilic gold nanoparticles perturb phase separation in multidomain lipid membranes Open
Experiments and simulations reveal that amphiphilic nanoparticles suppress phase separation in neuronal-like lipid bilayers and form bilayer-embedded ordered aggregates.