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View article: Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis
Distinctive waves of innate immune response in the retina in experimental autoimmune encephalomyelitis Open
Neurodegeneration mediates neurological disability in inflammatory demyelinating diseases of the CNS. The role of innate immune cells in mediating this damage has remained controversial with evidence for destructive and protective effects.…
View article: Characterization of a Cytomegalovirus-Specific T Lymphocyte Product Obtained Through a Rapid and Scalable Production Process for Use in Adoptive Immunotherapy
Characterization of a Cytomegalovirus-Specific T Lymphocyte Product Obtained Through a Rapid and Scalable Production Process for Use in Adoptive Immunotherapy Open
Immunosuppressed patients are susceptible to virus reactivation or de novo infection. Adoptive immunotherapy, based on virus-specific T lymphocytes (VST), can prevent or treat viral diseases. However, donor availability, HLA-compatibility …
Association Between Serum Neurofilament Light Chain Levels and Long-term Disease Course Among Patients With Multiple Sclerosis Followed up for 12 Years Open
This study found that statistically significant associations of sNFL with relevant clinical and neuroimaging outcomes in MS were confirmed and extended, supporting the potential of sNFL as an objective surrogate of ongoing MS disease activ…
Multiple sclerosis genetics Open
A broad scientific consensus has emerged linking multiple sclerosis (MS) risk to multiple independent and interacting DNA variants that are relatively frequent in the population and act in concert with environmental exposures. The multifac…
Additional file 4: of Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients Open
Table S3. Comparison of levels of phosphorylated proteins between MS patients and controls after in vitro stimulation. Levels of phosphorylated proteins in each cell type in healthy controls and RRMS patients. Values represent the mean flu…