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View article: Mandibular osteomyelitis and Lemierre's syndrome following third molar extraction in a young adult – A case report
Mandibular osteomyelitis and Lemierre's syndrome following third molar extraction in a young adult – A case report Open
Lemierre's syndrome is a rare condition that involves septic thrombophlebitis of the internal jugular vein (IJV) most commonly as a complication of oropharyngeal bacterial infections. It is even more rare in association with infection foll…
View article: Association between muscle strength and echogenicity using greyscale ultrasound software: a diagnostic accuracy study in kidney transplant candidates
Association between muscle strength and echogenicity using greyscale ultrasound software: a diagnostic accuracy study in kidney transplant candidates Open
Early identification of muscle weakness would advance efforts to mitigate morbidity and mortality through targeted measures.
View article: Frailty and sarcopenia metabolomic signatures in kidney transplant candidates: the FRAILMar study
Frailty and sarcopenia metabolomic signatures in kidney transplant candidates: the FRAILMar study Open
Background Sarcopenia and frailty are often overlooked in assessing kidney transplant (KT) candidates with chronic kidney disease (CKD), potentially leading to poor post-transplant outcomes. This study aimed to identify metabolites associa…
View article: Emotional, physiological, biochemical, and behavioral responses to acute stress and uncertainty in military personnel
Emotional, physiological, biochemical, and behavioral responses to acute stress and uncertainty in military personnel Open
Stress carries diverse implications for perceptual, cognitive, and affective functions. One population particularly susceptible to acute stress-induced cognitive changes are individuals with high-stress jobs (e.g., military personnel). The…
View article: Factors Influencing the Attrition Rate of a 10-Week Multimodal Rehabilitation Program in Patients After Lung Transplant: A Neural Network Analysis
Factors Influencing the Attrition Rate of a 10-Week Multimodal Rehabilitation Program in Patients After Lung Transplant: A Neural Network Analysis Open
Background/Objectives: Despite the effectiveness of exercise and nutritional interventions to improve aerobic capacity and quality of life in lung transplant (LT) recipients, their compliance is low. Strategies to reduce the high attrition…
View article: Resistance Training and Nutritional Supplementation in Older Adults with Sarcopenia after Acute Disease: A Feasibility Study
Resistance Training and Nutritional Supplementation in Older Adults with Sarcopenia after Acute Disease: A Feasibility Study Open
Resistance exercise and protein supplementation are recognized as effective treatment strategies for age-related sarcopenia; however, there are limited data on their feasibility, tolerability, and safety. The primary outcome of this study …
View article: Phase Angle as Surrogate Marker of Muscle Weakness in Kidney Transplant Candidates Referred to Prehabilitation
Phase Angle as Surrogate Marker of Muscle Weakness in Kidney Transplant Candidates Referred to Prehabilitation Open
Phase angle (PhA), a marker of nutritional status obtained by bioelectrical impedance analysis (BIA), is associated with the integrity of cell membranes. Damage to muscle fiber membranes can impact muscle strength, which is related to adve…
View article: State and trait predictors of cognitive responses to acute stress and uncertainty
State and trait predictors of cognitive responses to acute stress and uncertainty Open
Stress occurs when conditions burden or exceed an individual's adaptive resources. Military personnel are often tasked with maintaining peak performance under such stressful conditions. Importantly, the effects of stress are nuanced and ma…
View article: Effects of Exercise Training on Circulating Biomarkers of Endothelial Function in Pulmonary Arterial Hypertension
Effects of Exercise Training on Circulating Biomarkers of Endothelial Function in Pulmonary Arterial Hypertension Open
Introduction: In stable patients with pulmonary arterial hypertension (PAH), pulmonary rehabilitation (PR) is an effective, safe and cost-effective non-pharmacological treatment. However, the effects of PR on vascular function have been po…
View article: Treatment of COVID-19 during the Acute Phase in Hospitalized Patients Decreases Post-Acute Sequelae of COVID-19
Treatment of COVID-19 during the Acute Phase in Hospitalized Patients Decreases Post-Acute Sequelae of COVID-19 Open
Background: The post-acute sequelae of SARS-CoV-2 (PASC) infection have caused a significant impact on our health system, but there is limited evidence of approved drugs focused on its prevention. Our objective was to identify risk factors…
View article: Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Data from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Data from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Trabectedin (Yondelis; ET-743) is a potent anticancer drug that binds to DNA by forming a covalent bond with a guanine in one strand and one or more hydrogen bonds with the opposite strand. Using a fluorescence-based melting assay, we show…
View article: Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S3 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S1 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Supplementary Fig. S2 from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
View article: Data from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin
Data from Relevance of the Fanconi anemia pathway in the response of human cells to trabectedin Open
Trabectedin (Yondelis; ET-743) is a potent anticancer drug that binds to DNA by forming a covalent bond with a guanine in one strand and one or more hydrogen bonds with the opposite strand. Using a fluorescence-based melting assay, we show…
View article: Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Data from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Data from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Trabectedin (Yondelis) is a potent antitumor drug that has the unique characteristic of killing cells by poisoning the DNA nucleotide excision repair (NER) machinery. The basis for the NER-dependent toxicity has not yet been elucidated but…
View article: Association between Malnutrition Assessed by the Global Leadership Initiative on Malnutrition Criteria and Mortality in Older People: A Scoping Review
Association between Malnutrition Assessed by the Global Leadership Initiative on Malnutrition Criteria and Mortality in Older People: A Scoping Review Open
The Global Leadership Initiative on Malnutrition (GLIM) criteria were introduced in 2018 for the diagnosis of malnutrition in adults. This review was aimed at gathering the evidence about the association between malnutrition according to t…
View article: Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Data from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Data from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Trabectedin (Yondelis) is a potent antitumor drug that has the unique characteristic of killing cells by poisoning the DNA nucleotide excision repair (NER) machinery. The basis for the NER-dependent toxicity has not yet been elucidated but…
View article: Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Figure S1 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Table S1, Methods and Materials from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin Open
Supplementary Figure S2 from Cross-Talk between Nucleotide Excision and Homologous Recombination DNA Repair Pathways in the Mechanism of Action of Antitumor Trabectedin
View article: Intensive Rehabilitation Program in Older Adults with Stroke: Therapy Content and Feasibility—Preliminary Results from the BRAIN-CONNECTS Study
Intensive Rehabilitation Program in Older Adults with Stroke: Therapy Content and Feasibility—Preliminary Results from the BRAIN-CONNECTS Study Open
The main objective was to assess the feasibility of an intensive rehabilitation program (IRP) for stroke patients; and secondly, to detect eventual age-related differences in content, duration, tolerability, and safety in a prospective obs…
View article: Low Phase Angle Values Are Associated with Malnutrition according to the Global Leadership Initiative on Malnutrition Criteria in Kidney Transplant Candidates: Preliminary Assessment of Diagnostic Accuracy in the FRAILMar Study
Low Phase Angle Values Are Associated with Malnutrition according to the Global Leadership Initiative on Malnutrition Criteria in Kidney Transplant Candidates: Preliminary Assessment of Diagnostic Accuracy in the FRAILMar Study Open
Malnutrition has a negative impact on patients with chronic diseases and its early identification is a priority. The primary objective of this diagnostic accuracy study was to assess the performance of the phase angle (PhA), a bioimpedance…