Esther A. Olanudun
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View article: Flavonoid in All Their Therapeutic Values: An Odyssey into the Phytochemistry and Pharmacology of Naturally Occurring Flavonoid from Genus Bauhinia
Flavonoid in All Their Therapeutic Values: An Odyssey into the Phytochemistry and Pharmacology of Naturally Occurring Flavonoid from Genus Bauhinia Open
The genus Bauhinia has over 350 species distributed on different continents of the world. The vast majority of the species in this genus possess interesting biological activities. Also, they are good sources of flavonoids, which are known …
View article: Elucidating the monoamine oxidase B inhibitory effect of kaurene diterpenoids from Xylopia aethiopica: An in silico approach
Elucidating the monoamine oxidase B inhibitory effect of kaurene diterpenoids from Xylopia aethiopica: An in silico approach Open
Parkinson disease is a neurogenerative disease common in adults and results in different kinds of memory dysfuntions. This study evaluated the monoamine oxidase B (MAO-B) inhibitory potential of kaurane diterpenoids previously isolated fro…
View article: Unraveling the Antidiabetic Effect of <i>Alternantera brasiliana</i> (L.) Kuntze: A Combined <i>in Vitro</i> and <i>in Vivo</i> Approach
Unraveling the Antidiabetic Effect of <i>Alternantera brasiliana</i> (L.) Kuntze: A Combined <i>in Vitro</i> and <i>in Vivo</i> Approach Open
Background of the study This study established the antidiabetic efficacy of Alternantera brasiliana in vitro and in vivo, identified the most active fraction and profiled the chemical constituents of the most active fraction. Methodology T…
View article: Deciphering the influenza neuraminidase inhibitory potential of naturally occurring biflavonoids: An <i>in silico</i> approach
Deciphering the influenza neuraminidase inhibitory potential of naturally occurring biflavonoids: An <i>in silico</i> approach Open
Influenza infection poses a significant threat to the existence of humans and animals. Its inhibition by secondary metabolites may proffer a lasting solution to its resistance to available synthetic therapeutic agents. In this study, we in…
View article: Investigating the multitargeted anti-diabetic potential of cucurbitane-type triterpenoid from <i>Momordica charantia</i>: an LC-MS, docking-based MM\GBSA and MD simulation study
Investigating the multitargeted anti-diabetic potential of cucurbitane-type triterpenoid from <i>Momordica charantia</i>: an LC-MS, docking-based MM\GBSA and MD simulation study Open
Type 2 diabetes accounts for the largest percentage of all diabetic cases worldwide. Cucurbitane-type triterpenes are mainly found in Momordica charantia and possess excellent pharmacological activities. This study was designed to i…