Esther M. Levasseur
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View article: Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis
Hypusine biosynthesis in β cells links polyamine metabolism to facultative cellular proliferation to maintain glucose homeostasis Open
β Cell proliferation in response to insulin resistance requires hypusination of an mRNA translation factor.
View article: Episodic β‐cell death and dedifferentiation during diet‐induced obesity and dysglycemia in male mice
Episodic β‐cell death and dedifferentiation during diet‐induced obesity and dysglycemia in male mice Open
Loss of functional islet '‐cell mass through cellular death or dedifferentiation is thought to lead to dysglycemia during the βrogression from obesity to ty'e 2 diabetes. To assess these 'rocesses in a mouse model of obesity, we performed …