Ethan Stancliffe
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View article: Effects of Dietary Medium-Chain Triglyceride Supplementation on the Serum Metabolome of Young Adult and Senior Canines
Effects of Dietary Medium-Chain Triglyceride Supplementation on the Serum Metabolome of Young Adult and Senior Canines Open
In dogs, brain aging may lead to cognitive decline and cognitive dysfunction syndrome (CDS) [...]
View article: Iron Accumulation and Metabolic Alterations in Aneurysmal Subarachnoid Hemorrhage
Iron Accumulation and Metabolic Alterations in Aneurysmal Subarachnoid Hemorrhage Open
Background Aneurysmal subarachnoid hemorrhage (aSAH) is a severe type of stroke that is associated with poor outcome. A subset of patients with aSAH will develop secondary complications, most notably delayed cerebral ischemia (DCI), which …
View article: An Untargeted Metabolomics Workflow that Scales to Thousands of Samples for Population-Based Studies
An Untargeted Metabolomics Workflow that Scales to Thousands of Samples for Population-Based Studies Open
The success of precision medicine relies upon collecting data from many individuals at the population level. Although advancing technologies have made such large-scale studies increasingly feasible in some disciplines such as genomics, the…
View article: A Workflow to Perform Targeted Metabolomics at the Untargeted Scale on a Triple Quadrupole Mass Spectrometer
A Workflow to Perform Targeted Metabolomics at the Untargeted Scale on a Triple Quadrupole Mass Spectrometer Open
The thousands of features commonly observed when performing untargeted metabolomics with quadrupole time-of-flight (QTOF) and Orbitrap mass spectrometers often correspond to only a few hundred unique metabolites of biological origin, which…
View article: e-stan/DecoID: DecoID
e-stan/DecoID: DecoID Open
Metabolomics software for database-assisted deconvolution of MS/MS spectra
View article: Longitudinal Metabolomics of Human Plasma Reveals Robust Prognostic Markers of COVID-19 Disease Severity
Longitudinal Metabolomics of Human Plasma Reveals Robust Prognostic Markers of COVID-19 Disease Severity Open
There is an urgent need to identify which COVID-19 patients will develop life-threatening illness so that scarce medical resources can be optimally allocated and rapid treatment can be administered early in the disease course, when clinica…
View article: Dose-Response Metabolomics To Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software
Dose-Response Metabolomics To Understand Biochemical Mechanisms and Off-Target Drug Effects with the TOXcms Software Open
Small-molecule drugs and toxicants commonly interact with more than a single protein target, each of which may have unique effects on cellular phenotype. Although untargeted metabolomics is often applied to understand the mode of action of…