Etsuko Miyagi
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View article: Single sperm karyotyping of testicular sperm in non-obstructive and obstructive azoospermia using next generation sequencing
Single sperm karyotyping of testicular sperm in non-obstructive and obstructive azoospermia using next generation sequencing Open
The sperm of infertile men have higher rates of chromosomal abnormalities than those of fertile men. Miscarriage rate is also higher following testicular sperm extraction combined with intracytoplasmic sperm injection (TESE-ICSI). Sperm ch…
View article: The Short‐Term Impacts of Japan's 2024 Physician Working‐Hour Limits on Labor Conditions, Self‐Directed Professional Development, and Happiness Among Obstetrician‐Gynecologists
The Short‐Term Impacts of Japan's 2024 Physician Working‐Hour Limits on Labor Conditions, Self‐Directed Professional Development, and Happiness Among Obstetrician‐Gynecologists Open
Objective To examine the short‐term impacts of Japan's newly implemented physician working‐hour limits (April 2024) on working conditions, self‐directed professional development (SDPD), defined as activities undertaken outside working hour…
View article: Efficacy and Safety of Concurrent Chemoradiotherapy as First‐Line Treatment for Stage <scp>IVB</scp> Cervical Cancer: A Single‐Center Retrospective Observational Study
Efficacy and Safety of Concurrent Chemoradiotherapy as First‐Line Treatment for Stage <span>IVB</span> Cervical Cancer: A Single‐Center Retrospective Observational Study Open
Aim To evaluate the efficacy and safety of concurrent chemoradiotherapy prior to systemic chemotherapy in patients with stage IVB cervical cancer. Methods This retrospective observational study included 40 patients diagnosed with stage IVB…
View article: Postpartum diabetes screening for women with gestational diabetes in Japan: an administrative database study
Postpartum diabetes screening for women with gestational diabetes in Japan: an administrative database study Open
Objectives To estimate uptake of the 75 g oral glucose tolerance test (OGTT) at 6–12 weeks postpartum among women with gestational diabetes mellitus (GDM) in Japan, and to explore the demographic and clinical characteristics associated wit…
View article: Survival After Fertility-Preserving Hormonal Therapy vs Hysterectomy for Early-Stage Endometrial Cancer
Survival After Fertility-Preserving Hormonal Therapy vs Hysterectomy for Early-Stage Endometrial Cancer Open
Importance As the number of young women with early-stage endometrial cancer is increasing, there is growing interest in use of progesterone-based therapy to allow fertility preservation. Objective To ascertain the long-term survival of pre…
View article: Survey on Awareness and Attitudes Toward Maternal Immunization Against Influenza, Pertussis, Respiratory Syncytial Virus, and Group B Streptococcus Among Pregnant Women in Japan
Survey on Awareness and Attitudes Toward Maternal Immunization Against Influenza, Pertussis, Respiratory Syncytial Virus, and Group B Streptococcus Among Pregnant Women in Japan Open
Background/Objective: Maternal immunization is highly recommended, particularly in developed countries. However, its awareness among pregnant women in Japan remains low. This study aimed to assess the awareness and attitudes toward materna…
View article: Web-Based Video Intervention and Associated Factors for the Uptake of the Catch-Up Human Papillomavirus Vaccination in Japan: Randomized Controlled Trial
Web-Based Video Intervention and Associated Factors for the Uptake of the Catch-Up Human Papillomavirus Vaccination in Japan: Randomized Controlled Trial Open
Background In Japan, the human papillomavirus (HPV) vaccination rate has dropped to nearly zero since the suspension of proactive government recommendations in 2013. Following the termination of vaccination suspension in 2021 and subsequen…
View article: Assessment of tissue factor pathway inhibitor 2 (<scp>TFPI2</scp>) as a novel serum marker for malignant tumors of the ovary before and after treatment: A case‐control study
Assessment of tissue factor pathway inhibitor 2 (<span>TFPI2</span>) as a novel serum marker for malignant tumors of the ovary before and after treatment: A case‐control study Open
Aim Tissue factor pathway inhibitor 2 (TFPI2) is a preoperative biomarker that was developed to discriminate ovarian benign tumors from cancer and is covered by health insurance in Japan. The purpose of this study was to evaluate how the T…
View article: Radiation‐induced congenital malformations in Fukushima after the Fukushima Daiichi Nuclear Disaster
Radiation‐induced congenital malformations in Fukushima after the Fukushima Daiichi Nuclear Disaster Open
The Fukushima Daiichi Nuclear Disaster (FDND) occurred in 2011, which occurred after the Great East Japan Earthquake. However, how the incidence of radiation‐induced malformations in Fukushima has been affected by FDND remains to be elucid…
View article: Karyotype and phenotype association in Turner syndrome with non‐mosaic X chromosome structural rearrangements: Systematic review
Karyotype and phenotype association in Turner syndrome with non‐mosaic X chromosome structural rearrangements: Systematic review Open
Turner syndrome is a chromosomal disorder, characterized by the partial or total deletion of one X chromosome, resulting in various karyotypes that presumably lead to different phenotypes. However, most studies find it difficult to predict…
View article: Maternal and neonatal outcomes of occiput posterior vaginal delivery
Maternal and neonatal outcomes of occiput posterior vaginal delivery Open
ABSRACT Aim The occiput posterior (OP) position is the most common fetal malposition associated with poorer maternal outcomes compared to the occiput anterior (OA) position. However, there are no equivalent reports for women in Japan. This…
View article: Effect Of Web-Based Educational Video on the Uptake of the Catch-Up Human Papilloma Virus Vaccinations Among Unvaccinated Women in Japan: A Randomized Controlled Trial (Preprint)
Effect Of Web-Based Educational Video on the Uptake of the Catch-Up Human Papilloma Virus Vaccinations Among Unvaccinated Women in Japan: A Randomized Controlled Trial (Preprint) Open
BACKGROUND In Japan, the human papillomavirus (HPV) vaccination rate has dropped to nearly zero since the suspension of proactive government recommendations in 2013. Following the termination of vaccination suspension in 2021 and subseque…
View article: Human papillomavirus vaccine to prevent <scp>CIN3</scp> or worse (<scp>CIN3</scp>+): A nationwide case–control study in Japan
Human papillomavirus vaccine to prevent <span>CIN3</span> or worse (<span>CIN3</span>+): A nationwide case–control study in Japan Open
An increase in cervical cancer incidence has been reported in Japan. The Ministry of Health, Labor, and Welfare of Japan has resumed the active recommendation of regular HPV vaccines in 2022. In Japan, the preventive effect of CIN3+ in the…
View article: Tissue factor pathway inhibitor-2 inhibits integrin β1 activation and focal adhesion formation and suppresses peritoneal ovarian cancer dissemination in mice
Tissue factor pathway inhibitor-2 inhibits integrin β1 activation and focal adhesion formation and suppresses peritoneal ovarian cancer dissemination in mice Open
Tissue factor pathway inhibitor-2 (TFPI2) is a Kunitz-type serine protease inhibitor and an ovarian clear cell carcinoma (CCC) biomarker. TFPI2 is expressed in several cancers and exerts tumor-suppressive effects; however, the role of TFPI…
View article: Risk factors for positive cervical cytology during early pregnancy screening and awareness of positive cytological results in Japan: a report from the Pregnant Women Health Initiative
Risk factors for positive cervical cytology during early pregnancy screening and awareness of positive cytological results in Japan: a report from the Pregnant Women Health Initiative Open
Objective Cervical cancer screening rates are low in Japan. Therefore, when a woman is pregnant, this is a good opportunity to visit an obstetrics and gynecology clinic to have cervical cytology. This study aimed to clarify the association…
View article: Three‐year questionnaire study on human papillomavirus vaccination targeting new female college school students: Follow‐up to a 2021 report to reveal the impact of a policy change in Japan
Three‐year questionnaire study on human papillomavirus vaccination targeting new female college school students: Follow‐up to a 2021 report to reveal the impact of a policy change in Japan Open
Aim The purpose of this study was to examine the trend in human papillomavirus (HPV) vaccination rates in Japan before and after a policy change in 2022, involving resumption of active recommendation and start of catch‐up vaccination. Meth…
View article: Sarcopenia shortens overall survival of patients with platinum-resistant recurrent ovarian cancer: inverse probability of treatment-weighting analysis
Sarcopenia shortens overall survival of patients with platinum-resistant recurrent ovarian cancer: inverse probability of treatment-weighting analysis Open
Sarcopenia significantly shortened the overall survival of patients with platinum-resistant recurrent ovarian cancer.
View article: Impact of changes in recommendation of optimal gestational weight gain in Japan: A retrospective study in a single tertiary center
Impact of changes in recommendation of optimal gestational weight gain in Japan: A retrospective study in a single tertiary center Open
Aim In March 2021, the Japanese Ministry of Health, Labour and Welfare revised the optimal gestational weight gain standards. In this study, we examined whether this revision affected gestational weight gain and low birth weight rates. Met…
View article: Human papillomavirus (<scp>HPV</scp>) vaccination in Japan
Human papillomavirus (<span>HPV</span>) vaccination in Japan Open
Aim To review the status of human papillomavirus (HPV) vaccination in Japan from inception to the present, focusing on past and current challenges. Methods Published articles and website content related to HPV vaccination were reviewed. Re…
View article: Is there a need for screening of cervical HPV infections and carcinoma?
Is there a need for screening of cervical HPV infections and carcinoma? Open
Antenatal cervical screening aims to detect cervical intraepithelial neoplasms as precancerous lesions and invasive cervical cancer. Whether this screening is performed routinely during pregnancy varies depending on each country's screenin…
View article: Impact of interpregnancy weight changes and perinatal outcomes: A retrospective study in Japan
Impact of interpregnancy weight changes and perinatal outcomes: A retrospective study in Japan Open
Previous studies have shown that interpregnancy weight fluctuations impact perinatal outcomes. In order to examine this in Japanese women, we analyzed the data of 2,861 women in their first and second pregnancies who delivered singletons b…
View article: Frequency of Cul-de-sac Obliteration in Surgery for Pelvic Organ Prolapse: A Retrospective Analysis
Frequency of Cul-de-sac Obliteration in Surgery for Pelvic Organ Prolapse: A Retrospective Analysis Open
Introduction and Hypothesis: We aimed to clarify the frequency of cul-de-sac obliteration in patients undergoing POP surgery. Methods: We retrospectively reviewed patients who underwent laparoscopic POP surgery at our hospital between Apri…
View article: Two cases of cervical cancer in pregnant women diagnosed as ASC-H by cytology
Two cases of cervical cancer in pregnant women diagnosed as ASC-H by cytology Open
背景:妊娠中の子宮頸がん検診は若年者の検診受診率を下支えしているが,妊娠の影響で過小評価されることがある.妊娠初期の子宮頸部細胞診が atypical squamous cells cannot exclude HSIL(ASC-H)と評価された進行子宮頸癌 2 例について浸潤癌の細胞診所見を示さなかった要因を検討した.