Ettore Marconi
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View article: Treatment choice for adult patients with moderate-to-severe asthma: the TAILOR study
Treatment choice for adult patients with moderate-to-severe asthma: the TAILOR study Open
Background In patients with uncontrolled asthma treated with medium dose inhaled corticosteroid/long-acting β 2 -agonist (ICS/LABA), the Global Initiative for Asthma (GINA) recommends to increase to high-dose ICS/LABA or to start therapy c…
View article: Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care
Pertussis Notification Rate and Tdpa Vaccine/Booster Coverage in Adults: An Opportunity for an Epidemiological Observatory in Primary Care Open
Background: In recent years, Europe has experienced a significant increase in pertussis cases. One reason behind this rise is the decline in diphtheria–tetanus–pertussis (dTap) booster coverage among adults. Currently, Italy lacks a reliab…
View article: Development and validation of a prediction score to assess the risk of incurring in COPD-related exacerbations: a population-based study in primary care
Development and validation of a prediction score to assess the risk of incurring in COPD-related exacerbations: a population-based study in primary care Open
View article: Development and validation of a prediction score to assess the risk of depression in primary care
Development and validation of a prediction score to assess the risk of depression in primary care Open
View article: A Vulnerability Index to Assess the Risk of SARS-CoV-2-Related Hospitalization/Death: Urgent Need for an Update after Diffusion of Anti-COVID Vaccines
A Vulnerability Index to Assess the Risk of SARS-CoV-2-Related Hospitalization/Death: Urgent Need for an Update after Diffusion of Anti-COVID Vaccines Open
Background: There are algorithms to predict the risk of SARS-CoV-2-related complications. Given the spread of anti-COVID vaccination, which sensibly modified the burden of risk of the infection, these tools need to be re-calibrated. Theref…
View article: Time lapses between distribution of influenza vaccines to health authorities and their administration by General Practitioners (GPs) to older adults: a retrospective study over five influenza seasons in Italy
Time lapses between distribution of influenza vaccines to health authorities and their administration by General Practitioners (GPs) to older adults: a retrospective study over five influenza seasons in Italy Open
These findings highlight the importance of minimizing the time lapse between vaccine distribution and administration to mitigate the impact of influenza and address factors that contribute to vaccination barriers.
View article: Drug utilization analysis of osteoporosis medications in seven European electronic health databases
Drug utilization analysis of osteoporosis medications in seven European electronic health databases Open
View article: To predict the risk of chronic kidney disease (CKD) using Generalized Additive2 Models (GA2M)
To predict the risk of chronic kidney disease (CKD) using Generalized Additive2 Models (GA2M) Open
Objective To train and test a model predicting chronic kidney disease (CKD) using the Generalized Additive2 Model (GA2M), and compare it with other models being obtained with traditional or machine learning approaches. Materials We adopted…
View article: Further data on use of NSAIDs for the home-care therapy of COVID-19
Further data on use of NSAIDs for the home-care therapy of COVID-19 Open
View article: “To clarify the safety profile of paracetamol for home-care patients with COVID-19: a real-world cohort study, with nested case–control analysis, in primary care”—Reply
“To clarify the safety profile of paracetamol for home-care patients with COVID-19: a real-world cohort study, with nested case–control analysis, in primary care”—Reply Open
View article: Early identification of chronic kidney disease: it is time to enhance patient and population-based informatics tools for general practitioners
Early identification of chronic kidney disease: it is time to enhance patient and population-based informatics tools for general practitioners Open
Chronic kidney disease (CKD) is a global public health issue that can lead to several complications such as, kidney failure, cerebro/cardiovascular disease, and death. There is a well-documented "awareness gap" among general practitioners …
View article: Frailty detection among primary care older patients through the Primary Care Frailty Index (PC-FI)
Frailty detection among primary care older patients through the Primary Care Frailty Index (PC-FI) Open
The prompt identification of frailty in primary care is the first step to offer personalized care to older individuals. We aimed to detect and quantify frailty among primary care older patients, by developing and validating a primary care …
View article: Epidemiology of pediatric psoriasis: a population-based study using two Italian data sources
Epidemiology of pediatric psoriasis: a population-based study using two Italian data sources Open
Psoriasis can be associated with certain comorbidities. This information is important for family pediatricians (FPs) and general practitioners (GPs) who have a key role in the identification and management of skin diseases. This study aime…
View article: Impact of COVID-19 pandemic on medication use in the older Italian population
Impact of COVID-19 pandemic on medication use in the older Italian population Open
View article: Potentially inappropriate prescribing before and after nursing home admission: a retrospective observational study in a sample of Italian nursing homes.
Potentially inappropriate prescribing before and after nursing home admission: a retrospective observational study in a sample of Italian nursing homes. Open
although the reduction of PIP after NH admission may suggest greater awareness about the appropriateness of drug use, more efforts still need to be made.
View article: To clarify the safety profile of paracetamol for home-care patients with COVID-19: a real-world cohort study, with nested case–control analysis, in primary care
To clarify the safety profile of paracetamol for home-care patients with COVID-19: a real-world cohort study, with nested case–control analysis, in primary care Open
View article: A Cohort Study on Influenza Vaccine and All-Cause Mortality in Older Adults: Methodological Concerns and Public Health Implications
A Cohort Study on Influenza Vaccine and All-Cause Mortality in Older Adults: Methodological Concerns and Public Health Implications Open
View article: Acute appendicitis in a patient immunised with COVID‐19 vaccine: A case report with morphological analysis
Acute appendicitis in a patient immunised with COVID‐19 vaccine: A case report with morphological analysis Open
Although the benefit/risk profile for mRNA COVID‐19 vaccines is recognised as extremely favourable, appendicitis is currently considered an adverse event (AE) of special interest. We describe the case of a 58‐year‐old female who presented …
View article: Clinical Decision Support System (CDSS) in primary care: from pragmatic use to the best approach to assess their benefit/risk profile in clinical practice
Clinical Decision Support System (CDSS) in primary care: from pragmatic use to the best approach to assess their benefit/risk profile in clinical practice Open
Clinical Decision Support Systems (CDSSs) are computer-based tools intended to support physicians in clinical decision making. MilleDSS is an illustrative example for the Italian context. It is featured by four domains of GP-software inter…
View article: Anti-COVID-19 vaccines and rare cases of cerebral venous sinus thrombosis with thrombocytopenia: what about the pragmatic benefit/risk evaluation for still unvaccinated young women
Anti-COVID-19 vaccines and rare cases of cerebral venous sinus thrombosis with thrombocytopenia: what about the pragmatic benefit/risk evaluation for still unvaccinated young women Open
View article: Adjuvanted versus non-adjuvanted standard-dose influenza vaccines in preventing all-cause hospitalizations in the elderly: a cohort study with nested case-control analyses over 18 influenza seasons
Adjuvanted versus non-adjuvanted standard-dose influenza vaccines in preventing all-cause hospitalizations in the elderly: a cohort study with nested case-control analyses over 18 influenza seasons Open
The higher effectiveness of adjuvanted trivalent influenza vaccine (aTIV) versus non-adjuvanted (na) formulations in preventing all-cause hospitalization has been demonstrated for a single influenza season and in institutionalized elderly …
View article: Treatment patterns for osteoporosis medications in five European countries: a multinational real world cohort analysis
Treatment patterns for osteoporosis medications in five European countries: a multinational real world cohort analysis Open
View article: Reduced effectiveness among β-lactam antibiotics: a population-based cohort study in primary care in Italy
Reduced effectiveness among β-lactam antibiotics: a population-based cohort study in primary care in Italy Open
Background There are few data comparing the relative effectiveness of the individual β-lactams. Objectives To quantify the reduced effectiveness, defined as switching to a different antibiotic being prescribed for the same indication, amon…
View article: Predicting the risk of severe COVID-19 outcomes in primary care: development and validation of a vulnerability index for equitable allocation of effective vaccines
Predicting the risk of severe COVID-19 outcomes in primary care: development and validation of a vulnerability index for equitable allocation of effective vaccines Open
General practitioners (GPs) need a valid, user-friendly tool to identify patients most vulnerable to COVID-19, especially in the hypothesis of a booster vaccine dose. The aim of this study was to develop and validate a GP-friendly prognost…
View article: Adherence to Triple-Free-Drug Combination Therapies Among Patients With Cardiovascular Disease
Adherence to Triple-Free-Drug Combination Therapies Among Patients With Cardiovascular Disease Open
View article: Efficacy and safety of pharmacological treatments for patent ductus arteriosus closure: A systematic review and network meta-analysis of clinical trials and observational studies
Efficacy and safety of pharmacological treatments for patent ductus arteriosus closure: A systematic review and network meta-analysis of clinical trials and observational studies Open
View article: Prescribing Trends of Codeine-containing Medications and Other Opioids in Primary Care After A Regulatory Decision: An Interrupted Time Series Analysis
Prescribing Trends of Codeine-containing Medications and Other Opioids in Primary Care After A Regulatory Decision: An Interrupted Time Series Analysis Open
View article: Adjuvanted versus nonadjuvanted influenza vaccines and risk of hospitalizations for pneumonia and cerebro/cardiovascular events in the elderly
Adjuvanted versus nonadjuvanted influenza vaccines and risk of hospitalizations for pneumonia and cerebro/cardiovascular events in the elderly Open
Background: The higher effectiveness of MF59®-adjuvanted trivalent influenza vaccine (MF59-TIV) vs. nonadjuvanted TIV in preventing influenza-related hospitalizations was found considering few influenza seasons, local and heterogene…
View article: Prescribing patterns of allopurinol and febuxostat according to directives on the reimbursement criteria and clinical guidelines: analysis of a primary care database
Prescribing patterns of allopurinol and febuxostat according to directives on the reimbursement criteria and clinical guidelines: analysis of a primary care database Open
Prescriptions of febuxostat were highly compliant to Nota 91. Only a sub-group of frontline prescriptions of febuxostat were mainly driven by the presence of renal dysfunction, which is able to increase the risk of allopurinol intolerance …
View article: Pattern of Use and Long-Term Safety of Tyrosine Kinase Inhibitors: A Decade of Real-World Management of Chronic Myeloid Leukemia
Pattern of Use and Long-Term Safety of Tyrosine Kinase Inhibitors: A Decade of Real-World Management of Chronic Myeloid Leukemia Open