Eugen Radu Boia
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View article: Cutis Marmorata Telangiectatica Congenita: Case Series and Literature Review
Cutis Marmorata Telangiectatica Congenita: Case Series and Literature Review Open
Background: Cutis marmorata telangiectatica congenita (CMTC) is a rare congenital vascular anomaly characterized by a persistent, violaceous, reticulated skin pattern. It may present as a benign isolated lesion or as part of a broader synd…
View article: Advancements in Hydrogels: A Comprehensive Review of Natural and Synthetic Innovations for Biomedical Applications
Advancements in Hydrogels: A Comprehensive Review of Natural and Synthetic Innovations for Biomedical Applications Open
In the rapidly evolving field of biomedical engineering, hydrogels have emerged as highly versatile biomaterials that bridge biology and technology through their high water content, exceptional biocompatibility, and tunable mechanical prop…
View article: Psychological Distress and Quality of Life in Patients with Laryngeal Cancer: A Review
Psychological Distress and Quality of Life in Patients with Laryngeal Cancer: A Review Open
Laryngeal cancer significantly affects not only survival but also core functions such as speech, swallowing, and breathing. These impairments often result in substantial psychological distress and reduced health-related quality of life (HR…
View article: Design and Evaluation of a Zingiber officinale–Kaolinite–Maltodextrin Delivery System: Antioxidant, Antimicrobial, and Cytotoxic Activity Assessment
Design and Evaluation of a Zingiber officinale–Kaolinite–Maltodextrin Delivery System: Antioxidant, Antimicrobial, and Cytotoxic Activity Assessment Open
Background/Objectives: Zingiber officinale Roscoe (Zingiberaceae) is widely recognized for its diverse biological activities; however, the stability and bioavailability of its bioactive compounds remain significant challenges. This study a…
View article: Advances in Nanotechnology-Based Cisplatin Delivery for ORL Cancers: A Comprehensive Review
Advances in Nanotechnology-Based Cisplatin Delivery for ORL Cancers: A Comprehensive Review Open
Otorhinolaryngological (ORL) cancers, including malignancies of the oral cavity, pharynx, and larynx, show significant challenges in oncology. Cisplatin, a platinum-based chemotherapy drug, remains a cornerstone of treatment but is often l…
View article: Effect of Coenzyme Q10 Supplementation on Cardiac Function and Quality of Life in Patients with Heart Failure: A Randomized Controlled Trial
Effect of Coenzyme Q10 Supplementation on Cardiac Function and Quality of Life in Patients with Heart Failure: A Randomized Controlled Trial Open
Background/Objectives: Heart failure remains a complex syndrome with high morbidity and mortality, highlighting the urgent need for alternative treatments that address underlying bioenergetic impairments. CoQ10, which plays a crucial role …
View article: Laryngeal Cancer in the Modern Era: Evolving Trends in Diagnosis, Treatment, and Survival Outcomes
Laryngeal Cancer in the Modern Era: Evolving Trends in Diagnosis, Treatment, and Survival Outcomes Open
Background/Objectives: Laryngeal cancer (LC), predominantly squamous cell carcinoma (SCC), represents a considerable health burden worldwide. Tumour subsite heterogeneity (supraglottic, glottic, subglottic) influences clinical behavior and…
View article: The Association Between Fisetin and Rutin Triggers an Enhanced Cytotoxicity in A431 and A375 Skin Cancer Cells
The Association Between Fisetin and Rutin Triggers an Enhanced Cytotoxicity in A431 and A375 Skin Cancer Cells Open
Background: Skin cancer is a public health problem and conventional treatments lead to multiple limitations that affect patients' well-being. Fisetin and rutin are two phytocompounds that have demonstrated versatile biological properties, …
View article: Long-Term Quality of Life and Functional Outcomes in Patients with Total Laryngectomy
Long-Term Quality of Life and Functional Outcomes in Patients with Total Laryngectomy Open
Background: Laryngeal cancer affects quality of life (QoL), speech, and swallowing. Total laryngectomy (TL) causes severe impairments, while partial laryngectomy (PL) and chemoradiotherapy (CRT) preserve the organ but yield variable outcom…
View article: Quantum Leap: Reshaping Genetic Diagnostics Using Quantum Computing
Quantum Leap: Reshaping Genetic Diagnostics Using Quantum Computing Open
This study investigates the use of quantum computing, particularly Grover's algorithm, to improve genetic diagnostics for DiGeorge syndrome compared to conventional computational techniques. We employed the IBM Qiskit framework to sim…
View article: Psychological Well-Being and Quality of Life in Laryngeal Cancer Patients across Tumor
Psychological Well-Being and Quality of Life in Laryngeal Cancer Patients across Tumor Open
Background/Objectives: Laryngeal cancer significantly impacts patients’ psychological well-being and quality of life (QoL). This study aims to evaluate the psychological impact and QoL in patients with laryngeal cancer, focusing on differe…
View article: Early Postnatal Administration of Erythropoietin and Its Association with Neurodevelopmental Outcomes and Incidence of Intraventricular Hemorrhage and Hypoxic-Ischemic Encephalopathy: A Four-Week Observational Study
Early Postnatal Administration of Erythropoietin and Its Association with Neurodevelopmental Outcomes and Incidence of Intraventricular Hemorrhage and Hypoxic-Ischemic Encephalopathy: A Four-Week Observational Study Open
This study aimed to investigate the impact of early erythropoietin (EPO) administration on the neurodevelopment of newborns, specifically focusing on its effects on hypoxic-ischemic encephalopathy (HIE) and intraventricular hemorrhage (IVH…
View article: Romanian Wild-Growing Chelidonium majus—An Emerging Approach to a Potential Antimicrobial Engineering Carrier System Based on AuNPs: In Vitro Investigation and Evaluation
Romanian Wild-Growing Chelidonium majus—An Emerging Approach to a Potential Antimicrobial Engineering Carrier System Based on AuNPs: In Vitro Investigation and Evaluation Open
Novel nanotechnology based on herbal products aspires to be a high-performing therapeutic platform. This study reports the development of an original engineering carrier system that jointly combines the pharmacological action of Chelidoniu…
View article: An Innovative Approach to a Potential Neuroprotective Sideritis scardica-Clinoptilolite Phyto-Nanocarrier: In Vitro Investigation and Evaluation
An Innovative Approach to a Potential Neuroprotective Sideritis scardica-Clinoptilolite Phyto-Nanocarrier: In Vitro Investigation and Evaluation Open
The cutting-edge field of nanomedicine combines the power of medicinal plants with nanotechnology to create advanced scaffolds that boast improved bioavailability, biodistribution, and controlled release. In an innovative approach to perfo…
View article: Inflammatory Markers in Neonates Born to Mothers With SARS-CoV-2 Infection During Pregnancy
Inflammatory Markers in Neonates Born to Mothers With SARS-CoV-2 Infection During Pregnancy Open
The COVID-19 pandemic has raised concerns about its impact on maternal and neonatal health. This study aimed to investigate the influence of maternal COVID-19 infection during pregnancy on neonatal inflammatory parameters. A retrospective …
View article: The Role of Erythropoietin in Preventing Anemia in the Premature Neonate
The Role of Erythropoietin in Preventing Anemia in the Premature Neonate Open
Recombinant human erythropoietin (rhEPO) treatment is an alternative to red blood cell (RBC) transfusions in neonates presenting anemia of prematurity (AOP). This study assesses the impact of early rhEPO administration on AOP (any stage) i…
View article: Does COVID-19 Infection during Pregnancy Increase the Appearance of Congenital Gastrointestinal Malformations in Neonates?
Does COVID-19 Infection during Pregnancy Increase the Appearance of Congenital Gastrointestinal Malformations in Neonates? Open
Background: COVID-19 was an infection that was capable of bringing the entire world to a standstill position within a period of days to months. Despite the advancements in the medical sector, the contagion was difficult to control and cost…
View article: Impact of the COVID-19 Pandemic on Contraception Awareness and Mental Well-Being in Teenagers and Young Adult Women: A Three-Year Cross-Sectional Analysis
Impact of the COVID-19 Pandemic on Contraception Awareness and Mental Well-Being in Teenagers and Young Adult Women: A Three-Year Cross-Sectional Analysis Open
During the COVID-19 pandemic, significant shifts occurred in reproductive health, especially among teenagers and young adult women in Romania. This study, conducted from 2020 to 2022, aimed to longitudinally assess contraceptive awareness …
View article: Associated Bacterial Coinfections in COVID-19-Positive Patients
Associated Bacterial Coinfections in COVID-19-Positive Patients Open
Background and Objectives: The aim of this study was to identify specific rhino- and oropharyngeal microbiological pathogens as well as associated comorbidities that favor SARS-CoV-2 infection and corelate them. Materials and Methods: This…
View article: The Role of Erythropoietin in the Prevention of Anemia in the Premature Newborn
The Role of Erythropoietin in the Prevention of Anemia in the Premature Newborn Open
Recombinant human erythropoietin (rhEPO) treatment is an alternative to erythrocyte transfusions in neonates with anemia of prematurity (AOP). This study assesses the impact of rhEPO administration within the first week of life on the inci…
View article: The Neutrophil-to-Lymphocyte Ratio (NLR) Can Predict Sepsis’s Presence and Severity in Malnourished Infants—A Single Center Experience
The Neutrophil-to-Lymphocyte Ratio (NLR) Can Predict Sepsis’s Presence and Severity in Malnourished Infants—A Single Center Experience Open
Sepsis represents one of the leading causes of death in newborns and infants, and prompt diagnosis is essential for achieving favorable outcomes. Regarding malnourished children with concurrent infection, most studies have focused, besides…
View article: The Follicular Dendritic Cells and HPV 18 Interrelation in Head and Neck Squamous Cell Carcinomas of the Larynx
The Follicular Dendritic Cells and HPV 18 Interrelation in Head and Neck Squamous Cell Carcinomas of the Larynx Open
Background and Objectives: Even if they are cells of controversial origin (mesenchymal, perivascular, or fibroblastic), follicular dendritic cells (FDC) are present in all organs. The aim of this study was to establish the FDC expression p…
View article: Circulating miRNA as a Biomarker in Oral Cancer Liquid Biopsy
Circulating miRNA as a Biomarker in Oral Cancer Liquid Biopsy Open
Oral cancer is currently challenging the healthcare system, with a high incidence among the population and a poor survival rate. One of the main focuses related to this malignancy is the urge to implement a viable approach for improving it…
View article: Macronutrients Management for Growth in Neonates with Congenital Gastrointestinal Malformation
Macronutrients Management for Growth in Neonates with Congenital Gastrointestinal Malformation Open
BACKGROUND Congenital gastrointestinal (GI) malformations are developmental disorders that can result in secondary intestinal failure. Nutrient intakes must be adapted according to the newborn's nutritional requirements based on frequent a…
View article: Heterogeneity of Blood Vessels and Assessment of Microvessel Density-MVD in Gingivitis
Heterogeneity of Blood Vessels and Assessment of Microvessel Density-MVD in Gingivitis Open
Gingivitis is a very common oral disease highly prevalent in adults that, if left untreated, can progress to periodontitis. It involves a complex and slow interaction between the host response and the oral microbiome represented by the den…
View article: Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania
Clinical Factors Associated with COVID-19 Severity in Chronic Hospitalized Infants and Toddlers: Data from a Center in the West Part of Romania Open
Background: The risk factors for developing a severe form of COVID-19 in young children are poorly understood. Methods: A single-center retrospective study was conducted to quantify and analyze the clinical risk profile of children admitte…
View article: AN INNOVATIVE APPROACH TO TREAT EARLY CHILDHOOD CARIES (ECC) USING SILVER DIAMINE FLOURIDE – A CASE REPORT
AN INNOVATIVE APPROACH TO TREAT EARLY CHILDHOOD CARIES (ECC) USING SILVER DIAMINE FLOURIDE – A CASE REPORT Open
Dental decay affects 4-86% of preschoolers (temporary dentition), and regarding mixed and permanent dentition, the percentage of affected children is between 27-86%. Caries lesions of the temporary teeth is the main dental problem that the…
View article: SPACE CONTROL IN MIXED DENTITION - SPACE MAINTAINERS
SPACE CONTROL IN MIXED DENTITION - SPACE MAINTAINERS Open
Maintaining the child's oral cavity in optimal health by preserving the morpho-functional integrity of primary teeth, given the influence they have on the growth and development of the stomatognathic system is the duty and responsibility o…
View article: Toward a Molecular Classification of the Head and Neck Squamous Cell Carcinoma
Toward a Molecular Classification of the Head and Neck Squamous Cell Carcinoma Open
The frequency of the squamous cell carcinoma of the head and neck is constantly increasing, with over 550.000 new cases registered globally each year. The conventional histopathological diagnosis most commonly indicates the squamous cell c…
View article: Management of laryngeal cancers in the ENT Clinic of Timisoara – a 4 year retrospective study
Management of laryngeal cancers in the ENT Clinic of Timisoara – a 4 year retrospective study Open
Introduction: Laryngeal cancers are common in clinical practice and are often mistreated, leading to a bad outcome. The objective of our study was to raise awareness to the high incidence of laryngeal cancers and to the importance of corre…