Eugene Golts
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View article: Early Experience of Physician-Modified Endografts for Total Aortic Arch Repair
Early Experience of Physician-Modified Endografts for Total Aortic Arch Repair Open
PMEG for total endovascular arch repair presents a possible alternative to open surgical repair or existing company manufactured arch devices in selected patients. Perioperative stroke and mortality risk and rate of reintervention with tot…
View article: One-year lung transplantation outcomes for engineered stone countertop workers with silicosis at a single center in Southern California, 2019 to 2023
One-year lung transplantation outcomes for engineered stone countertop workers with silicosis at a single center in Southern California, 2019 to 2023 Open
View article: Single-center perioperative management and 1-year heart transplantation outcomes for patients with adult congenital heart disease
Single-center perioperative management and 1-year heart transplantation outcomes for patients with adult congenital heart disease Open
View article: Primary central nervous system post-transplant lymphoproliferative Disorder in a lung transplant recipient despite reduction of immunosuppression
Primary central nervous system post-transplant lymphoproliferative Disorder in a lung transplant recipient despite reduction of immunosuppression Open
Lymphomas arising in the setting of immune deficiency and/or dysregulation, also known as post-transplant lymphoproliferative disorder (PTLD) is frequently associated with immunosuppressive therapies and the Epstein Barr Virus after solid …
View article: Lung Transplant Success in COVID-19 Patients Requiring V-V ECMO: One-Year Follow-Up
Lung Transplant Success in COVID-19 Patients Requiring V-V ECMO: One-Year Follow-Up Open
BACKGROUND Acute respiratory distress syndrome (ARDS) due to coronavirus 2019 (COVID-19) can result in severe disease requiring mechanical ventilatory support. A subset of these patients, however, demonstrate refractory hypoxemia/hypercarb…
View article: A national survey of immunosuppression adjustment in elderly lung transplant recipients
A national survey of immunosuppression adjustment in elderly lung transplant recipients Open
The proportion of elderly lung transplant recipients has increased substantially in recent years. The immunosuppressants required significantly increase the risk for infection and malignancy in the elderly population. However, there is a p…
View article: Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
Integrated multiomic analysis identifies TRIP13 as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis Open
View article: Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells
Context-dependent roles of mitochondrial LONP1 in orchestrating the balance between airway progenitor versus progeny cells Open
While all eukaryotic cells are dependent on mitochondria for function, in a complex tissue, which cell type and which cell behavior are more sensitive to mitochondrial deficiency remain unpredictable. Here, we show that in the mouse airway…
View article: Magnetic sphincter augmentation: A promising alternative to fundoplication for preserving lung function and protecting against chronic lung transplant rejection
Magnetic sphincter augmentation: A promising alternative to fundoplication for preserving lung function and protecting against chronic lung transplant rejection Open
Background: Early laparoscopic fundoplication (LF) has been shown to slow lung function decline in chronic lung disease (CLD) patients and lung transplant (LTx) recipients. Magnetic sphincter augmentation (MSA) has emerged as an effective …
View article: Frequency of Unplanned Readmissions Following Lung Transplantation During the SAR-COV-2 Pandemic When Hospital Resources Were Strained
Frequency of Unplanned Readmissions Following Lung Transplantation During the SAR-COV-2 Pandemic When Hospital Resources Were Strained Open
Despite the concerted efforts by lung transplant recipients (LTR) and their medical teams, hospital readmissions are common in the first year following transplantation. Reasons for unplanned readmissions include allograft rejection, infect…
View article: Low Mortality Associated with COVID-19 Infection in Lung Transplant Recipients at a Single Center
Low Mortality Associated with COVID-19 Infection in Lung Transplant Recipients at a Single Center Open
Lung Transplant Recipients (LTR) are particularly vulnerable to severe infection, hospitalization, and death due to community acquired respiratory viruses. As a result, the global SARS-Cov-2 pandemic poses a higher risk to this population.…
View article: Improved kidney function and one-year survival with transitioning from intravenous to enteral tacrolimus in lung transplant recipients
Improved kidney function and one-year survival with transitioning from intravenous to enteral tacrolimus in lung transplant recipients Open
Background: Acute kidney injury (AKI) is common after lung transplant and may increase risk of chronic kidney disease (CKD). Calcineurin inhibitors (CNIs) such as tacrolimus contribute to AKI risk. This study evaluated outcomes among lung …
View article: Integrated multiomic analysis identifies<i>TRIP13</i>as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis
Integrated multiomic analysis identifies<i>TRIP13</i>as a mediator of alveolar epithelial type II cell dysfunction in idiopathic pulmonary fibrosis Open
SUMMARY Idiopathic pulmonary fibrosis (IPF) is a lethal progressive lung disease urgently needing new therapies. Current treatments only delay disease progression, leaving lung transplant as the sole remaining option. Recent studies suppor…
View article: Magnetic Sphincter Augmentation: A Promising Alternative to Fundoplication for Preserving Lung Function and Protecting Against Chronic Lung Transplant Rejection
Magnetic Sphincter Augmentation: A Promising Alternative to Fundoplication for Preserving Lung Function and Protecting Against Chronic Lung Transplant Rejection Open
View article: Difference in immunosuppressant dose requirement when transitioning to isavuconazole from other azoles in thoracic transplant recipients
Difference in immunosuppressant dose requirement when transitioning to isavuconazole from other azoles in thoracic transplant recipients Open
The triazole antifungal isavuconazole (ISAVU) is used for prevention and treatment of fungal infections in solid organ transplant (SOT). SOT recipients commonly need to transition from one azole to another due to breakthrough infection, to…
View article: Sirolimus Long-Term Tolerability and Impact on Kidney Function in Lung Transplantation: A Single-Center Experience
Sirolimus Long-Term Tolerability and Impact on Kidney Function in Lung Transplantation: A Single-Center Experience Open
Sirolimus is a viable immunosuppressant option after lung transplant, which successfully allows for the reduction or withdrawal of the CNI, resulting in sustained improvement in kidney function.
View article: Pre-arterialization of coronary veins prior to retroperfusion of ischemic myocardium: percutaneous closure device
Pre-arterialization of coronary veins prior to retroperfusion of ischemic myocardium: percutaneous closure device Open
Background Chronic coronary retroperfusion to treat myocardial ischemia has previously failed due to edema and hemorrhage of coronary veins suddenly exposed to arterial pressures. The objective of this study was to selectively adapt the co…
View article: Robust Outcomes for Hispanic Lung Transplant Recipients in the United States
Robust Outcomes for Hispanic Lung Transplant Recipients in the United States Open
Race, while a social construct, has a strong effect on a person’s health. There is limited data on racial disparities within lung transplantation (LTx), especially for Hispanic recipients. Therefore, the aim of this study was to iden…
View article: Monitoring Survival Following Lung Transplantation with Inclusion of Unaccounted Risks
Monitoring Survival Following Lung Transplantation with Inclusion of Unaccounted Risks Open
Lung transplant (LTx) survival and quality of life have been steadily improving, partially from changes in candidate selection for transplantation. There are well-known high-risk factors that lead to poor LTx outcomes, which may be referre…
View article: Esophageal Inlet Patch: A Clinically Significant Entity in Advanced Pulmonary Disease and Lung Transplant Rejection
Esophageal Inlet Patch: A Clinically Significant Entity in Advanced Pulmonary Disease and Lung Transplant Rejection Open
Background: Esophageal inlet patch (IP) refers to heterotopic gastric mucosa in the cervical esophagus. Secretions from IP may produce symptoms of laryngopharyngeal reflux (LPR) and accelerate progression of lung disease. We aimed to chara…
View article: Heart and Lung Transplant for Mixed Connective Tissue Disease: A Case Report and Implications for Pretransplant Testing
Heart and Lung Transplant for Mixed Connective Tissue Disease: A Case Report and Implications for Pretransplant Testing Open
We present a case of end-stage lung disease secondary to mixed connective tissue disease (MCTD) with concomitant myocarditis found on explant at time of transplant. The patient is a 37-year-old man who was first diagnosed with interstitial…
View article: A Pilot Trial for Prevention of Hepatitis C Virus Transmission From Donor to Organ Transplant Recipient With Short-Course Glecaprevir/Pibrentasvir
A Pilot Trial for Prevention of Hepatitis C Virus Transmission From Donor to Organ Transplant Recipient With Short-Course Glecaprevir/Pibrentasvir Open
A 7-day course of glecaprevir/pibrentasvir started in the preoperative period prevented transmission of hepatitis C virus (HCV) from viremic donors to 10 HCV-negative recipients (2 heart, 1 lung, 6 kidney, 1 heart/kidney) with 100% sustain…
View article: Development of Host Immune Response to Bacteriophage in a Lung Transplant Recipient on Adjunctive Phage Therapy for a Multidrug-Resistant Pneumonia
Development of Host Immune Response to Bacteriophage in a Lung Transplant Recipient on Adjunctive Phage Therapy for a Multidrug-Resistant Pneumonia Open
Bacteriophage therapy is the use of viruses to kill bacteria for the treatment of antibiotic-resistant infections. Little is known about the human immune response following phage therapy. We report the development of phage-specific CD4+ T …
View article: Short Term Outcomes in Case Series of 21 Congenital Heart Disease Recipients of Heart or Dual-Solid Organ Transplants
Short Term Outcomes in Case Series of 21 Congenital Heart Disease Recipients of Heart or Dual-Solid Organ Transplants Open
View article: Short and Intermediate Term Effects of COVID-19 Infection on Lung Transplant Recipients
Short and Intermediate Term Effects of COVID-19 Infection on Lung Transplant Recipients Open
View article: Heart and Lung Transplant for Mixed Connective Tissue Disease: Implications for Pre-Transplant Testing
Heart and Lung Transplant for Mixed Connective Tissue Disease: Implications for Pre-Transplant Testing Open
View article: Utility of Plasma Microbial Cell-Free DNA Decay Kinetics After Aortic Valve Replacement for Bartonella Endocarditis: Case Report
Utility of Plasma Microbial Cell-Free DNA Decay Kinetics After Aortic Valve Replacement for Bartonella Endocarditis: Case Report Open
Background Detection and sequencing of circulating microbial cell-free DNA (mcfDNA) in plasma is an increasingly popular tool for diagnosing many infectious diseases, but could also be used to monitor the progress of infection. However, th…
View article: Experience with Alpha-1 Proteinase Replacement Post-Lung Transplantation in Alpha-1 Antitrypsin Deficiency: A Single Center Case Series
Experience with Alpha-1 Proteinase Replacement Post-Lung Transplantation in Alpha-1 Antitrypsin Deficiency: A Single Center Case Series Open
Alpha-1 antitrypsin deficiency (AATD) accounts for approximately 5% of lung transplants (LTx) performed annually. No studies have addressed the potential benefit of ongoing alpha-1 proteinase inhibitor (A1-PI) replacement to AATD patients …
View article: Novel Biomaterial for Artery Patch in Swine Model With High-Fat Diet
Novel Biomaterial for Artery Patch in Swine Model With High-Fat Diet Open
Objective We evaluated swine and bovine pulmonary visceral pleura (PVP) in artery patch-angioplasty in swine model of high-fat diet. Background Arterial patch-angioplasty is frequently used for repair or reconstruction of arteries. An auto…
View article: Implementation and Outcomes of a Mobile Extracorporeal Membrane Oxygenation Program in the United States During the Coronavirus Disease 2019 Pandemic
Implementation and Outcomes of a Mobile Extracorporeal Membrane Oxygenation Program in the United States During the Coronavirus Disease 2019 Pandemic Open
The coronavirus disease 2019 (COVID-19) pandemic began in the United States around March 2020. Because of limited access to extracorporeal membrane oxygenation (ECMO) in the authors' region, a mobile ECMO team was implemented by April 2020…